Magnetophoresis of flexible DNA-based dumbbell structures

Babic, Bakir, Ghai, Rajesh and Dimitrov, Krassen (2008) Magnetophoresis of flexible DNA-based dumbbell structures. Applied Physics Letters, 92 5: 053901-1-053901-3. doi:10.1063/1.2834698

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Author Babic, Bakir
Ghai, Rajesh
Dimitrov, Krassen
Title Magnetophoresis of flexible DNA-based dumbbell structures
Journal name Applied Physics Letters   Check publisher's open access policy
ISSN 0003-6951
Publication date 2008-02-07
Sub-type Article (original research)
DOI 10.1063/1.2834698
Open Access Status File (Publisher version)
Volume 92
Issue 5
Start page 053901-1
End page 053901-3
Total pages 3
Editor Nghi Q. Lam
Place of publication Melville, N.Y., U.S.A
Publisher American Institute of Physics
Collection year 2009
Language eng
Subject C1
029901 Biological Physics
970102 Expanding Knowledge in the Physical Sciences
Abstract Controlled movement and manipulation of magnetic micro- and nanostructures using magnetic forces can give rise to important applications in biomedecine, diagnostics, and immunology. We report controlled magnetophoresis and stretching, in aqueous solution, of a DNA-based dumbbell structure containing magnetic and diamagnetic microspheres. The velocity and stretching of the dumbbell were experimentally measured and correlated with a theoretical model based on the forces acting on individual magnetic beads or the entire dumbbell structures. The results show that precise and predictable manipulation of dumbbell structures is achievable and can potentially be applied to immunomagnetic cell separators. ©2008 American Institute of Physics
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
Australian Institute for Bioengineering and Nanotechnology Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 14 Apr 2009, 10:03:26 EST by Mrs Jennifer Brown on behalf of Aust Institute for Bioengineering & Nanotechnology