Investigation of pulse transit time characteristics during single and recurrent obstructive respiratory events

Foo, Jong Yong A., Wilson, Stephen J., Williams, Gordon R., Harris, Margaret-Ann and Cooper, David M. (2008) Investigation of pulse transit time characteristics during single and recurrent obstructive respiratory events. Journal of Clinical Monitoring and Computing, 22 4: 327-332. doi:10.1007/s10877-008-9137-9


Author Foo, Jong Yong A.
Wilson, Stephen J.
Williams, Gordon R.
Harris, Margaret-Ann
Cooper, David M.
Title Investigation of pulse transit time characteristics during single and recurrent obstructive respiratory events
Journal name Journal of Clinical Monitoring and Computing   Check publisher's open access policy
ISSN 1387-1307
1573-2614
Publication date 2008-08-01
Sub-type Article (original research)
DOI 10.1007/s10877-008-9137-9
Volume 22
Issue 4
Start page 327
End page 332
Total pages 6
Place of publication Netherlands
Publisher Springer Netherlands
Collection year 2009
Language eng
Subject C1
0903 Biomedical Engineering
730110 Respiratory system and diseases (incl. asthma)
Abstract Conventional overnight polysomnography (PSG) used to determine the respiratory behaviour during sleep can be a complex and expensive procedure. Pulse transit time analysis (PTT) has shown potential to detect obstructive apnoeic and hypopnoeic events (OE) in adults. Due to abnormalities in central ventilatory control, recurring OE may occur. This study was undertaken to determine the potential of PTT to differentiate responses during upper airway obstruction in the paediatric population. This preliminary study included 11 children (10 male; aged 7.5 ± 3.8 year) recruited to investigate PTT trend during single and recurrent OE. PTT measurements were evaluated against the corresponding PSG results pre-scored by two blinded obsercvers. A total of 110 valid OE (47 single and 63 recurrent) were observed during these PSG studies. There were distinct PTT responses observed for these two types of OE with respect to those of tidal breathing (P < 0.05). For the tidal breathing events, the mean absolute standard deviation (SD) and maximal percentage (%) decrease (MAX) were 7.71 ms and 3.88% respectively. For the recurrent OE, the absolute SD, SD (%) and MAX were 52.21 ms, 8.52% and 55.08% accordingly while for the single OE, the absolute SD, SD (%) and MAX were 12.23 ms, 5.27% and 13.56% respectively. The findings herein can suggest that PTT can be a valuable clinical tool in the paediatric respiratory sleep studies. © Springer Science+Business Media, LLC 2008.
Keyword cardiovascular
non-invasive monitoring
Paediatrics
photoplethysmography
sleep disordered breathing
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
School of Information Technology and Electrical Engineering Publications
 
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Created: Tue, 14 Apr 2009, 02:09:33 EST by Ms Kimberley Nunes on behalf of School of Information Technol and Elec Engineering