Insulin sensitivity is halved and fasting insulin concentration increased four times in spontaneously obese dogs

Verkest, K. R., Fleeman, L. M., Rand, J. S. and Morton, J. M. (2005). Insulin sensitivity is halved and fasting insulin concentration increased four times in spontaneously obese dogs. In: 2005 ACVIM: Abstracts published in the Journal of Veterinary Internal Medicine. ACVIM Forum, Annual Conference of the American College of Veterinary Internal Medicine, Baltimore, (424-425). 2005. doi:10.1111/j.1939-1676.2005.tb02714.x


Author Verkest, K. R.
Fleeman, L. M.
Rand, J. S.
Morton, J. M.
Title of paper Insulin sensitivity is halved and fasting insulin concentration increased four times in spontaneously obese dogs
Conference name ACVIM Forum, Annual Conference of the American College of Veterinary Internal Medicine
Conference location Baltimore
Conference dates 2005
Proceedings title 2005 ACVIM: Abstracts published in the Journal of Veterinary Internal Medicine   Check publisher's open access policy
Journal name Journal of Veterinary Internal Medicine   Check publisher's open access policy
Place of Publication Hoboken, N.J.
Publisher Wiley
Publication Year 2005
Sub-type Published abstract
DOI 10.1111/j.1939-1676.2005.tb02714.x
Open Access Status DOI
ISSN 0891-6640
Volume 19
Issue 3
Start page 424
End page 425
Total pages 2
Language eng
Abstract/Summary Type 2 diabetes mellitus occurs in human beings and cats when insulin secretion fails to compensate for obesity-induced insulin resistance. Although obese dogs develop insulin resistance, they are not known to progress to type 2 diabetes, and little is known about the long-term effects of obesity on insulin secretion in dogs. Previous studies of insulin secretion in obese dogs involved dogs with induced, short-term obesity, or were confounded by the inclusion of intact bitches, or used glucose tolerance tests that had insufficient early samples to assess first-phase insulin secretion. The aim of this study was to evaluate glucose tolerance and insulin secretion in dogs with spontaneous obesity.
Subjects 070704 Veterinary Epidemiology
Q-Index Code EX

 
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