A birth-weight questionnaire indicated that life style modifies the birth weight and metabolic syndrome relationship at age 36

te Velde, Saskia J., Twisk, Jos W.R., van Mechelen, W. and Kemper, Han C. G. (2005) A birth-weight questionnaire indicated that life style modifies the birth weight and metabolic syndrome relationship at age 36. Journal of Clinical Epidemiology, 58 11: 1172-1179.


Author te Velde, Saskia J.
Twisk, Jos W.R.
van Mechelen, W.
Kemper, Han C. G.
Title A birth-weight questionnaire indicated that life style modifies the birth weight and metabolic syndrome relationship at age 36
Journal name Journal of Clinical Epidemiology   Check publisher's open access policy
ISSN 0895-4356
1878-5921
Publication date 2005-11
Sub-type Article (original research)
DOI 10.1016/j.jclinepi.2005.03.013
Volume 58
Issue 11
Start page 1172
End page 1179
Total pages 8
Place of publication United States
Publisher Elsevier
Language eng
Subject 1117 Public Health and Health Services
Formatted abstract Objective:
Investigating the relationship between birth weight and the metabolic syndrome and the modifying effects of lifestyle in adults (36.5 years).

Study Design and Setting:
273 subjects completed a birth-weight questionnaire; waist circumference, HDL and triglyceride concentrations, blood pressure and HbA1c, physical activity and fitness, smoking status and dietary intake were measured. Risks for the metabolic syndrome and for having at least two of the components of the metabolic syndrome were calculated and the modifying effect of lifestyle factors was assessed by comparing four groups based on birth weight and a lifestyle factor.

Results:
Birth weight was not associated with the metabolic syndrome (odds ratio OR = 0.67, 95% confidence interval CI = 0.25–1.79). Birth weight lower than the median increased the risk for having at least two components (OR = 2.28, 95% CI = 1.15–4.50). Subjects who smoked and had a birth weight lower than the median had a 6.9 times increased risk. Modification by lifestyle measured at age 36 was not observed, although effect modification using lifestyle data from 32 years was found.

Conclusions:
Lower birth weight increased the risk for having at least two components of the metabolic syndrome. Smoking, being less physical active or fit, have an unfavorable diet at age 32 adds to this risk.


Keyword Birth weight
Metabolic syndrome
Lifestyle
Adults
Effect modification
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Human Movement Studies Publications
 
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