Low numbers of intestinal Shiga toxin-producing E. coli correlate with a poor prognosis in sheep infected with bovine leukemia virus

Ferens, W.A., Haruna, J., Cobbold, Rowland N. and Hovde, C.J. (2008) Low numbers of intestinal Shiga toxin-producing E. coli correlate with a poor prognosis in sheep infected with bovine leukemia virus. Journal of Veterinary Science, 9 4: 375-379. doi:10.4142/jvs.2008.9.4.375


Author Ferens, W.A.
Haruna, J.
Cobbold, Rowland N.
Hovde, C.J.
Title Low numbers of intestinal Shiga toxin-producing E. coli correlate with a poor prognosis in sheep infected with bovine leukemia virus
Journal name Journal of Veterinary Science   Check publisher's open access policy
ISSN 1229-845X
Publication date 2008
Sub-type Article (original research)
DOI 10.4142/jvs.2008.9.4.375
Open Access Status DOI
Volume 9
Issue 4
Start page 375
End page 379
Total pages 5
Editor Lee, H.S.
Place of publication Republic of Korea
Publisher Korean Society of Veterinary Science
Collection year 2009
Language eng
Subject C1
070706 Veterinary Medicine
830310 Sheep - Meat
830311 Sheep - Wool
Abstract Healthy ruminants carry intestinal Shiga toxin (Stx)-¡¡ producing Escherichia coli (STEC). Stx has antiviral activities in vitro and STEC numbers correlate with reduced early viremia in sheep experimentally infected with bovine leukemia virus (BLV). This study assessed the impact of intestinal STEC on BLV-induced disease for one year post-BLV-challenge. High STEC scores (CFU/g feces ¡¿ frequency of STEC-positive samples) correlated with good health, whereas poor weight gain, distress, and tumor development occurred only among animals with low STEC scores. STEC carriage was associated with increased percentages of B cells in peripheral blood.
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
School of Veterinary Science Publications
 
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Created: Thu, 19 Mar 2009, 14:31:52 EST by Narelle Poole on behalf of School of Veterinary Science