The 8 year functional and symptomatic outcome of first episode psychosis (FEP)

Henry, L. P., Harris, M. G., Schwartz, O. S., Farrelly, S., Prosser, A. L., Yuen, H. P., Herrman, H. and McGorry, P. D. (2005). The 8 year functional and symptomatic outcome of first episode psychosis (FEP). In: Schizophrenia Bulletin. Abstracts of the The 10th International Congress on Schizophrenia Research. The 10th International Congress on Schizophrenia Research, Savannah, Georgia, (224-224). 2–6 April 2005. doi:10.1093/schbul/sbi024

Author Henry, L. P.
Harris, M. G.
Schwartz, O. S.
Farrelly, S.
Prosser, A. L.
Yuen, H. P.
Herrman, H.
McGorry, P. D.
Title of paper The 8 year functional and symptomatic outcome of first episode psychosis (FEP)
Conference name The 10th International Congress on Schizophrenia Research
Conference location Savannah, Georgia
Conference dates 2–6 April 2005
Proceedings title Schizophrenia Bulletin. Abstracts of the The 10th International Congress on Schizophrenia Research   Check publisher's open access policy
Journal name Schizophrenia Bulletin   Check publisher's open access policy
Place of Publication Rockville, Md., U.S.A.
Publisher Oxford University Press
Publication Year 2005
DOI 10.1093/schbul/sbi024
ISSN 0586-7614
Volume 31
Issue 2
Start page 224
End page 224
Total pages 1
Language eng
Abstract/Summary The study purpose is to examine the 8-year functional and symptomatic outcome of a FEP cohort of 800 patients in addition to the course patterns of psychosis over time. The design is a naturalistic, prospective, longitudinal, 8-year follow-up study with multiple follow- up time points, on a representative multidiagnostic cohort of 800 patients with FEP from the Early Psychosis Prevention and Intervention Centre, which is a frontline public mental health service and its precursor service in Melbourne, Australia. Recruitment is ongoing. The preliminary results which follow concern the 470 subjects who have been interviewed to date. At 8-year outcome, analyses indicate that 74% remain unmarried, 54% are either working, studying or are homemakers. Mean scores on quality of life and social functioning measures indicate functioning in the good range. 75% are currently receiving psychiatric treatment, however 45% of these were being treated in the private health sector suggesting less severe illness and better functioning. Those taking an antipsychotic were on a CPZ equivalent mean low dose of 303mg. In terms of psychiatric hospital admission, 60% have not been admitted in the most recent two years and the mean number of admissions over the 8-year period was two. 47% have not been psychotic in the most recent 2 years and one quarter never had another psychotic episode after recovering from their first episode. Mean scores on psychopathology measures indicate minimal to low levels of current psychopathology. Comparison of these findings with the existing outcome literature of similar follow- up duration should be made with caution as the majority are of first episode schizophrenia. However our data concerning course type over the most recent two years is consistent with the findings of Mason et al. (1995) and Robinson et al. (2004). However our findings concerning the never psychotic course type over the entire follow- up period differs to that found by Thara et al. (1994). Our study reported a higher percentage (24%) than Thara et al. (1994) (17%) who had not been psychotic during the intervening years and over half of this group had completely remitted. Over half of our cohort was fully occupationally engaged compared with 19% reported by the Scottish Schizophrenia Research Group (1992). The findings from this study suggest patients with psychotic disorders can achieve symptomatic remission and good social and occupational functioning 8-years post FEP.
Subjects 1103 Clinical Sciences
1117 Public Health and Health Services
Keyword EPPIC 800
Cohort study
Early psychosis
Q-Index Code EX

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Created: Fri, 13 Mar 2009, 11:18:19 EST by Ms Karen Naughton on behalf of Faculty Of Health Sciences