Bone geometric response to chronic disuse following stroke: A pQCT study

Ashe, M. C., Fehling, P., Eng, J. J., Khan, K. M. and McKay, H. A. (2006) Bone geometric response to chronic disuse following stroke: A pQCT study. Journal of Musculoskeletal and Neuronal Interactions, 6 3: 226-233.

Author Ashe, M. C.
Fehling, P.
Eng, J. J.
Khan, K. M.
McKay, H. A.
Title Bone geometric response to chronic disuse following stroke: A pQCT study
Journal name Journal of Musculoskeletal and Neuronal Interactions   Check publisher's open access policy
ISSN 1108-7161
Publication date 2006-09
Sub-type Article (original research)
Volume 6
Issue 3
Start page 226
End page 233
Total pages 8
Place of publication Athens, Greece
Publisher International Society of Musculoskeletal and Neuronal Interactions
Language eng
Subject 1116 Medical Physiology
Abstract The objectives of this study were to 1) assess volumetric bone geometry and density at the distal radius of individuals with chronic stroke and 2) assess whether bone strength is associated with measures of muscle strength and impairment. Material and methods: Cross-sectional study of bone and muscle parameters in 15 community-dwelling people living with the residual effects of a stroke (between 1 and 9 years post-incident stroke). Results: The 4% site of the distal radius had significantly lower bone mineral content and density on the paretic side (p<0.006). There was a significant difference in pQCT measures of bone cortical density (p<0.03), area (p<0.05) and bone strength [Stress-Strain Index; SSI] (p<0.01) (lower on the paretic side) at the 30%. We found significant correlations between composite muscle strength score of the upper extremities and pQCT-generated bone strength. Conclusions: This cross-sectional study highlights lower bone strength on the paretic limb and an adaptive response to disuse.
Keyword Stroke
Peripheral Quantitative Computed Tomography (pQCT)
Muscle strength
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Human Movement and Nutrition Sciences Publications
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Created: Mon, 09 Mar 2009, 16:39:43 EST by Paul Rollo on behalf of Faculty Of Health Sciences