Activation of the MAPK Module from Different Spatial Locations Generates Distinct System Outputs

Inder, K., Harding, A., Plowman, S. J., Philips, M. R., Parton, R. G. and Hancock, J. F. (2008) Activation of the MAPK Module from Different Spatial Locations Generates Distinct System Outputs. Molecular Biology of the Cell, 19 11: 4776-4784. doi:10.1091/mbc.E08-04-0407

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Author Inder, K.
Harding, A.
Plowman, S. J.
Philips, M. R.
Parton, R. G.
Hancock, J. F.
Title Activation of the MAPK Module from Different Spatial Locations Generates Distinct System Outputs
Journal name Molecular Biology of the Cell   Check publisher's open access policy
ISSN 1939-4586
1939-4586
Publication date 2008-08-05
Year available 2008
Sub-type Article (original research)
DOI 10.1091/mbc.E08-04-0407
Open Access Status File (Publisher version)
Volume 19
Issue 11
Start page 4776
End page 4784
Total pages 8
Place of publication Bethesda
Publisher The American Society for Cell Biology
Collection year 2009
Language eng
Subject 060112 Structural Biology (incl. Macromolecular Modelling)
970106 Expanding Knowledge in the Biological Sciences
C1
Abstract The Ras/Raf/MEK/ERK (MAPK) pathway directs multiple cell fate decisions within a single cell. How different system outputs are generated in unknown. Here we explore whether activating the MAPK module from different membrane environments can rewire system output.
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collection: 2009 Higher Education Research Data Collection
 
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Created: Thu, 26 Feb 2009, 12:31:09 EST by Cody Mudgway on behalf of Institute for Molecular Bioscience