Young's modulus of a switchable peptide film

Middelberg, Anton P. J., He, Lizhong, Dexter, Annette F., Shen, Hsin-hui, Holt, Stephen A. and Thomas, Robert K. (2007). Young's modulus of a switchable peptide film. In: , American Chemical Society 234th National Meeting & Exposition. American Chemical Society 234th National Meeting & Exposition, Boston, USA, (). 19-23 August, 2007.


Author Middelberg, Anton P. J.
He, Lizhong
Dexter, Annette F.
Shen, Hsin-hui
Holt, Stephen A.
Thomas, Robert K.
Title of paper Young's modulus of a switchable peptide film
Conference Paper Type Fully Published Paper
Conference name American Chemical Society 234th National Meeting & Exposition
Conference location Boston, USA
Conference dates 19-23 August, 2007
Proceedings title American Chemical Society 234th National Meeting & Exposition
Place published Boston, MA USA
Publisher American Chemical Society
Publication date 2007
Language eng
Abstract/Summary We report the structure and Young's modulus of switchable films formed by peptide self-assembly at the air-water interface. Peptide AM1 forms an interfacial film that can be switched reversibly from a high- to a low-elasticity state, accompanied by rapid loss of stability in peptide-containing emulsions or foams. By neutron reflectometry, we find the AM1 film comprises a thin (ca. 15 Å) monolayer of folded peptide in both states, confirming that it is possible to alter the mechanical properties of an interfacial ensemble without significantly altering its architecture. Based on the film thickness, we report the first experimentally determined Young's modulus for a peptide film self-assembled at a fluid interface (E = 80 MPa for AM1, switching to E < 20 MPa). The findings suggest a fundamental link between E and the macroscopic stability of peptide-containing foams and emulsions
Subjects 100703 Nanobiotechnology
030403 Characterisation of Biological Macromolecules
Keyword Peptide
Architecture
Film thickness
Q-Index Code EX

 
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Created: Wed, 18 Feb 2009, 12:42:15 EST by Alexandra Cooney on behalf of Aust Institute for Bioengineering & Nanotechnology