Inulin-type fructans of longer degree of polymerization exert more pronounced in vitro prebiotic effects

Van De Wiele, T., Boon, N., Possemiers, S., Jacobs, H. and Verstraete, W. (2007) Inulin-type fructans of longer degree of polymerization exert more pronounced in vitro prebiotic effects. Journal of Applied Bacteriology, 102 2: 452-460. doi:10.1111/j.1365-2672.2006.03084.x


Author Van De Wiele, T.
Boon, N.
Possemiers, S.
Jacobs, H.
Verstraete, W.
Title Inulin-type fructans of longer degree of polymerization exert more pronounced in vitro prebiotic effects
Journal name Journal of Applied Bacteriology   Check publisher's open access policy
ISSN 0021-8847
Publication date 2007-02
Sub-type Article (original research)
DOI 10.1111/j.1365-2672.2006.03084.x
Volume 102
Issue 2
Start page 452
End page 460
Total pages 9
Place of publication London
Publisher Blackwell Scientific
Language eng
Subject 110801 Medical Bacteriology
Abstract Two short chain fructans – oligofructose (DP 2–20) and inulin (DP 3–60) – were administered to the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) at 2·5 g day−1. The influence of fructan addition towards fermentation activity and microbial community composition from the different SHIME colon compartments were evaluated. Both fructans exerted prebiotic effects with significantly higher butyrate and propionate production and stimulation of lactic acid-producing bacteria. Compared with oligofructose, it was noted that it took more time before significant effects from inulin addition were observed. Yet, the higher short-chain fatty acid production and lower proteolytic activity showed that the prebiotic effects from inulin were more pronounced than oligofructose. Also, the bifidogenic effects from inulin vs oligofructose were higher in the distal colon compartments and this effect was prolonged in the distal colon once the addition was stopped.
Keyword Gut microbiota
Microflora
Functional food
Realtime PCR
Gastrointestinal tract
Lactobacilli
Bifidobacteria
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
Advanced Water Management Centre Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 109 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 125 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 13 Feb 2009, 17:34:26 EST by Paul Rollo on behalf of Advanced Water Management Centre