Towards a response model for dendritic cell immunotherapy of advanced metastatic melanoma

Schmidt, Christopher, Martinez, Nathan R., Neller, Michelle, Lai, M., Lopez, Jose Alejandro, Lanagan, Catherine M., O'Connor, Linda E., Nicholas, D., Johnson, Maree K., See, Janet L., Hallt, S., Slater, Gregory J., O'Rourke, Michael G. E., Pavey, Sandra, Hayward, Nick and Ellem, Kay A. O. (2005). Towards a response model for dendritic cell immunotherapy of advanced metastatic melanoma. In: Abstracts fo the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA & Immunogenetics Workshop. 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, Melbourne, VIC, Australia, (533-533). 29 November - 2 December 2005. doi:10.1111/j.1399-0039.2005.00523.x


Author Schmidt, Christopher
Martinez, Nathan R.
Neller, Michelle
Lai, M.
Lopez, Jose Alejandro
Lanagan, Catherine M.
O'Connor, Linda E.
Nicholas, D.
Johnson, Maree K.
See, Janet L.
Hallt, S.
Slater, Gregory J.
O'Rourke, Michael G. E.
Pavey, Sandra
Hayward, Nick
Ellem, Kay A. O.
Title of paper Towards a response model for dendritic cell immunotherapy of advanced metastatic melanoma
Conference name 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops
Conference location Melbourne, VIC, Australia
Conference dates 29 November - 2 December 2005
Proceedings title Abstracts fo the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA & Immunogenetics Workshop   Check publisher's open access policy
Journal name Tissue Antigens   Check publisher's open access policy
Place of Publication Malden, MA , U.S.A.
Publisher Wiley-Blackwell Publishing
Publication Year 2005
Sub-type Published abstract
DOI 10.1111/j.1399-0039.2005.00523.x
ISSN 0001-2815
1399-0039
Volume 66
Issue 5
Start page 533
End page 533
Total pages 1
Language eng
Abstract/Summary Cancer immunotherapy trials conducted over the last few years have concentrated on the analysis of immunological markers of response to antigenically well defined vaccines. Improvements in the quantity or quality of T cell responses, in a patient population, are proposed to allow a rational basis for improved clinical outcomes. However, using current methodologies, only weak immune correlates of clinical response have been found. Further, little attention has been given to other patient or tumour characteristics predisposing to favourable clinical responses following immunotherapy. Establishing such correlates is fundamental to understanding how vaccines work. We have followed this line of investigation with a matured, autologous, dendritic cell/irradiated melanoma cell vaccine for Stage IV melanoma patients
Subjects 110709 Tumour Immunology
Q-Index Code EX
Q-Index Status Provisional Code
Institutional Status Unknown
Additional Notes In Tissue Antigens 66(5) article is under heading 'Genetics and The Immune Response'Abstracts of the 35th Annual Scientific Meeting of the Australasian Society for Immunology and 14th International HLA & Immunogenetics Workshop. page 533

 
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