Course and prognostic factors of whiplash: A systematic review and meta-analysis

Kamper, Steven J., Rebbeck, Trudy J., Maher, Christopher G., McAudley, James H. and Sterling, Michele (2008) Course and prognostic factors of whiplash: A systematic review and meta-analysis. Pain, 138 3: 617-629. doi:10.1016/j.pain.2008.02.019

Author Kamper, Steven J.
Rebbeck, Trudy J.
Maher, Christopher G.
McAudley, James H.
Sterling, Michele
Title Course and prognostic factors of whiplash: A systematic review and meta-analysis
Journal name Pain   Check publisher's open access policy
ISSN 0304-3959
Publication date 2008
Year available 2008
Sub-type Article (original research)
DOI 10.1016/j.pain.2008.02.019
Volume 138
Issue 3
Start page 617
End page 629
Total pages 13
Editor Allan I. Basbaum
Place of publication USA
Publisher Elsevier
Collection year 2009
Language eng
Subject 321024 Rehabilitation and Therapy - Occupational and Physical
920116 Skeletal System and Disorders (incl. Arthritis)
Abstract We conducted a systematic review and meta-analysis of prospective cohort studies of subjects with acute whiplash injuries. The aim was to describe the course of recovery, pain and disability symptoms and also to assess the influence of different prognostic factors on outcome. Studies were selected for inclusion if they enrolled subjects with neck pain within six weeks of a car accident and measured pain and/or disability outcomes. Studies were located via a sensitive search of electronic databases; Medline, Embase, CINAHL, Cochrane database, ACP Journal club, DARE and Psychinfo and through hand-searches of relevant previous reviews. Methodological quality of all studies was assessed using a six item checklist. Sixty-seven articles, describing 38 separate cohorts were included. Recovery rates were extremely variable across studies but homogeneity was improved when only data from studies of more robust methodological quality were considered. These data suggest that recovery occurs for a substantial proportion of subjects in the initial 3 months after the accident but after this time recovery rates level off. Pain and disability symptoms also reduce rapidly in the initial months after the accident but show little improvement after 3 months have elapsed. Data regarding the prognostic factors associated with poor recovery were difficult to interpret due to heterogeneity of the techniques used to assess such associations and the way in which they are reported. There was also wide variation in the measurement of outcome and the use of validated measures would improve interpretability and comparability of future studies.
Keyword Whiplash
Systematic review
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2009 Higher Education Research Data Collection
Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 115 times in Thomson Reuters Web of Science Article | Citations
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Created: Thu, 05 Feb 2009, 12:19:04 EST by Chesne McGrath on behalf of National Research on Disability and Rehabilitation Medicine