Investigation of nanocomposites based on semi-interpenetrating networkof [l-poly (e-caprolactone)]/[net-poly (e-caprolactone)]and hydroxyapatite nanocrystals

Hao, Jianyuan, Liu, Yu, Zhou, Shaobing, Li, Zhen and Deng, Xianmo (2003) Investigation of nanocomposites based on semi-interpenetrating networkof [l-poly (e-caprolactone)]/[net-poly (e-caprolactone)]and hydroxyapatite nanocrystals. Biomaterials, 24 9: 1531-1539. doi:10.1016/S0142-9612(02)00516-1

Author Hao, Jianyuan
Liu, Yu
Zhou, Shaobing
Li, Zhen
Deng, Xianmo
Title Investigation of nanocomposites based on semi-interpenetrating networkof [l-poly (e-caprolactone)]/[net-poly (e-caprolactone)]and hydroxyapatite nanocrystals
Journal name Biomaterials   Check publisher's open access policy
ISSN 0142-9612
Publication date 2003-04
Sub-type Article (original research)
DOI 10.1016/S0142-9612(02)00516-1
Volume 24
Issue 9
Start page 1531
End page 1539
Total pages 9
Place of publication Oxford
Publisher Elsevier
Language eng
Subject 030306 Synthesis of Materials
030302 Nanochemistry and Supramolecular Chemistry
030603 Colloid and Surface Chemistry
030605 Solution Chemistry
030701 Quantum Chemistry
Abstract In this paper the semi-interpenetrating network(semi-IPN) technique was used for the first time to prepare bone implant composites containing hydroxyapatite (HAP) nanocrystals. The prepared nanocomposites are expected to combine several property advantages including good mechanical strength, modified degradation rate and excellent osteoconductivity. The semi-IPN matrix based on the linear poly (e-caprolactone) (l-PCL) and the networkpoly (e-caprolactone) (net-PCL) structures are revealed to be phase separation structures. The morphology of net-PCL is featured by intracrosslinked microdomains (1–10 mm) that further interconnect with each other to form the networkover the whole sample. The net-PCL component is totally amorphous at room temperature for the nanocomposites containing HAP up to 12.3 wt%. Further, the crystallinity of l-PCL is greatly decreased due to the presence of net-PCL as compared with that for pure l-PCL. The incorporation of l-PCL into the net-PCL networkcould significantly improve the mechanical properties of pure net-PCL. A great improvement in mechanical properties is observed for the nanocomposites if the HAP content is increased to 15.8 wt%. This transition is in agreement with that the net-PCL component changes from amorphous state to crystalline state at this composition.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Chemical Engineering Publications
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