Dermoscopy of facial nonpigmented actinic keratosis

Zalaudek, I., Giacomel, J., Argenziano, G., Hofmann-Wellenhof, R., Micantonio, T., Di Stefani, A., Oliviero, M., Rabinovitz, H., Soyer, H. P. and Peris, K. (2006) Dermoscopy of facial nonpigmented actinic keratosis. British Journal of Dermatology, 155 5: 951-956. doi:10.1111/j.1365-2133.2006.07426.x

Author Zalaudek, I.
Giacomel, J.
Argenziano, G.
Hofmann-Wellenhof, R.
Micantonio, T.
Di Stefani, A.
Oliviero, M.
Rabinovitz, H.
Soyer, H. P.
Peris, K.
Title Dermoscopy of facial nonpigmented actinic keratosis
Journal name British Journal of Dermatology   Check publisher's open access policy
ISSN 0007-0963
Publication date 2006-11
Year available 2006
Sub-type Article (original research)
DOI 10.1111/j.1365-2133.2006.07426.x
Volume 155
Issue 5
Start page 951
End page 956
Total pages 6
Place of publication United Kingdom
Publisher Wiley-Blackwell Publishing
Language eng
Subject 110304 Dermatology
Formatted abstract
The accuracy of clinical diagnosis of nonpigmented, facial actinic keratosis (AK) is often suboptimal, even for experienced clinicians.

To investigate the dermoscopic features of nonpigmented AK located on the head/neck that may assist the clinical diagnosis. Methods Forty-one nonpigmented AKs on facial sites were examined by dermoscopy for any consistent underlying features. Lesions were gathered from skin cancer centres in Australia, Austria, Italy and the U.S.A. All cases were diagnosed histopathologically.

Four essential dermoscopic features were observed in facial AK: (i) erythema, revealing a marked pink-to-red 'pseudonetwork' surrounding the hair follicles (95%); (ii) white-to-yellow surface scale (85%); (iii) fine, linear-wavy vessels surrounding the hair follicles (81%); and (vi) hair follicle openings filled with yellowish keratotic plugs (66%) and/or surrounded by a white halo (100%). These features combined, in 95% of cases, to produce a peculiar 'strawberry' appearance.


A dermoscopic model of 'strawberry' pattern is presented, which may prove helpful in the in vivo diagnosis of nonpigmented, facial AK. A limitation of this study is the lack of testing of the specificity of the described dermoscopic criteria in differentiating nonpigmented AKs from other nonpigmented skin lesions at this site
Keyword Actinic keratosis
Skin cancer
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Medicine Publications
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Created: Fri, 16 Jan 2009, 14:56:34 EST by Ms Lynette Adams on behalf of School of Medicine