Nicotine addiction through a neurogenomic prism: Ethics, public health, and smoking

Caron, L., Karkazis, K., Raffin, T. A., Swan, G. and Koenig, B. A. (2005) Nicotine addiction through a neurogenomic prism: Ethics, public health, and smoking. Nicotine and Tobacco Research, 7 2: 181-197. doi:10.1080/14622200500055251


Author Caron, L.
Karkazis, K.
Raffin, T. A.
Swan, G.
Koenig, B. A.
Title Nicotine addiction through a neurogenomic prism: Ethics, public health, and smoking
Journal name Nicotine and Tobacco Research   Check publisher's open access policy
ISSN 1462-2203
1469-994X
Publication date 2005-04
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1080/14622200500055251
Volume 7
Issue 2
Start page 181
End page 197
Total pages 17
Place of publication Oxford, U.K.
Publisher Oxford University Press
Language eng
Subject 1117 Public Health and Health Services
Abstract Studies are under way to examine the neurogenetic factors contributing to smoking behaviors. The combined approaches of genomics, molecular biology, neuroscience, and pharmacology are expected to fuel developments in pharmacogenetics, to create new genetic tests, and ultimately to provide the basis for innovative strategies for smoking cessation and prevention. The emergence of a neurogenomic understanding of nicotine addiction is likely to induce fundamental changes in popular, clinical, and public health views of smoking, which could significantly shape existing practices and policies to reduce tobacco use. Still a nascent area of research, nicotine addiction provides an excellent case study through which to anticipate key ethical and policy issues in both behavioral genetics and the neurogenomics of addictive behaviors.
Keyword Dopamine-receptor gene
Serotonin transporter gene
Single nucleotide polymorphism
Tryptophan-hydroxylase gene
Human-Genome-Project
Cigarette-smoking
Psychiatric gentics
Cytochrome-p450 2a6
Allelic Association
Drug-addiction
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: ERA 2012 Admin Only
School of Public Health Publications
 
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Created: Thu, 28 Aug 2008, 17:36:51 EST