Addiction is a brain disease, and it matters

Leshner, Alan I. (1997) Addiction is a brain disease, and it matters. Science, 278 5335: 45-47.


Author Leshner, Alan I.
Title Addiction is a brain disease, and it matters
Journal name Science   Check publisher's open access policy
ISSN 0036-8075
1095-9203
Publication date 1997
Sub-type Article (original research)
DOI 10.1126/science.278.5335.45
Volume 278
Issue 5335
Start page 45
End page 47
Total pages 3
Place of publication Washington, D. C.
Publisher American Association for the Advancement of Science
Language eng
Subject 11 Medical and Health Sciences
Abstract Scientific advances over the past 20 years have shown that drug addiction is a chronic, relapsing disease that results from the prolonged effects of drugs on the brain. As with many other brain diseases, addiction has embedded behavioral and social-context aspects that are important parts of the disorder itself. Therefore, the most effective treatment approaches will include biological, behavioral, and social-context components. Recognizing addiction as a chronic, relapsing brain disorder characterized by compulsive drug seeking and use can impact society's overall health and social policy strategies and help diminish the health and social costs associated with drug abuse and addiction.
Keyword INJECTION-DRUG USERS
MOLECULAR MECHANISMS
COCAINE
ABUSE
ADAPTATIONS
BEHAVIOR
PATHWAYS
EXPOSURE
SYSTEM
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Thu, 28 Aug 2008, 16:41:18 EST