Changes in consensus arylamine N-acetyltransferase gene nomenclature

Hein, David W., Boukouvala, Sotiriab, Grant, Denis M., Minchin, Rodney F. and Sim, Edith (2008) Changes in consensus arylamine N-acetyltransferase gene nomenclature. Pharmacogenetics and Genomics, 18 4: 367-368. doi:10.1097/FPC.0b013e3282f60db0


Author Hein, David W.
Boukouvala, Sotiriab
Grant, Denis M.
Minchin, Rodney F.
Sim, Edith
Title Changes in consensus arylamine N-acetyltransferase gene nomenclature
Journal name Pharmacogenetics and Genomics   Check publisher's open access policy
ISSN 1744-6872
1744-6880
Publication date 2008-04
Sub-type Article (original research)
DOI 10.1097/FPC.0b013e3282f60db0
Open Access Status
Volume 18
Issue 4
Start page 367
End page 368
Total pages 2
Editor M. Eichelbaum
W. E. Evans
Place of publication London, United Kingdom
Publisher Lippincott Williams & Wilkins
Collection year 2009
Language eng
Subject 111201 Cancer Cell Biology
920102 Cancer and Related Disorders
0604 Genetics
1115 Pharmacology and Pharmaceutical Sciences
Abstract Changes in consensus arylamine N-acetyltransferase (NAT) gene nomenclature determined at the 2007 International NAT Workshop include: (1) Alleles in all species except mouse and rat are all uppercase. For mouse and rat, the first letter is upper case followed by lower case. (2) The nomenclature system is now species-specific. Thus, NAT2*1 (chicken), NAT2*2 and NAT2*3 (rabbit), Nat2*8 Nat2*9, Nat2*22 and Nat2*23 (mouse), NAT2*15, NAT2*16A and NAT2*16B (Syrian hamster), and NAT2*20, NAT2*21A and NAT2*21B (rat) are retired and renumbered within a species. A species modifier incorporated into the allele designation is written in upper case Roman font, e.g., (MOUSE)Nat1*1 is now the reference Nat1 allele in mouse; and (3) The NAT website also can now be accessed at a webalias address: http://N-acetyltransferasenomenclature.louisville.edu. New NAT alleles should continue to be submitted to the NAT Nomenclature Committee for inclusion on the website to ensure proper categorization and to continue consistency in nomenclature. © 2008 Lippincott Williams & Wilkins, Inc.
Keyword N-acetyltransferase
Gene nomenclature
Allele nomenclature
Q-Index Code CX
Q-Index Status Provisional Code

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Biomedical Sciences Publications
 
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Created: Tue, 29 Jul 2008, 16:18:49 EST