Report of the international equine gene mapping workshop: Male linkage map

Guérin, G., Bailey, E., Bernoco, D., Anderson, I., Antczak, D. F., Bell, Thomas Kevin, Binns, M. M., Bowling, A. T., Brandon, Richard Bruce, Cholewinski, G., Cothran, E. G., Ellegren, H., Förster, J., Godard, S., Horin, P., Ketchum, M., Lindgren, G., McPartlan, H., Mériaux, J.-C., Mickelson, J. R., Millon, L. V., Murray, J, Neau, A, Røed, K, Sandberg, K, Shiue, Y.-L., Skow, L. C., Stott, M., Swinburne, J., Valberg, S. J., Van Haeringen, H., Van Haeringen, W. A. and Ziegle, Z. (1999) Report of the international equine gene mapping workshop: Male linkage map. Animal Genetics, 30 5: 341-354. doi:10.1046/j.1365-2052.1999.00510.x

Author Guérin, G.
Bailey, E.
Bernoco, D.
Anderson, I.
Antczak, D. F.
Bell, Thomas Kevin
Binns, M. M.
Bowling, A. T.
Brandon, Richard Bruce
Cholewinski, G.
Cothran, E. G.
Ellegren, H.
Förster, J.
Godard, S.
Horin, P.
Ketchum, M.
Lindgren, G.
McPartlan, H.
Mériaux, J.-C.
Mickelson, J. R.
Millon, L. V.
Murray, J
Neau, A
Røed, K
Sandberg, K
Shiue, Y.-L.
Skow, L. C.
Stott, M.
Swinburne, J.
Valberg, S. J.
Van Haeringen, H.
Van Haeringen, W. A.
Ziegle, Z.
Title Report of the international equine gene mapping workshop: Male linkage map
Journal name Animal Genetics   Check publisher's open access policy
ISSN 0268-9146
Publication date 1999-10
Sub-type Article (original research)
DOI 10.1046/j.1365-2052.1999.00510.x
Volume 30
Issue 5
Start page 341
End page 354
Total pages 14
Place of publication Oxford, U.K.
Publisher Blackwell Scientific Publications
Collection year 1999
Language eng
Subject C1
270200 Genetics
630107 Minor livestock (e.g. horses, goats, deer)
Formatted abstract
The goal of the First International Equine Gene Mapping Workshop, held in 1995, was the construction of a low density, male linkage map for the horse. For this purpose, the International Horse Reference Family Panel (IHRFP) was established, consisting of 12 paternal half-sib families with 448 half-sib offspring provided by 10 laboratories. Blood samples were collected and DNA extracted in each laboratory and sent to the Lexington laboratory (KY, USA) for dispatch in aliquots to 14 typing laboratories. In total, 161 markers (144 microsatellites, seven blood groups and 10 proteins) were tested for all families for which the sire was heterozygous. Genealogies and typing data were sent for analysis to the INRA laboratory (Jouy-en-Josas, France) according to a specific format and entered into a database with input verification and output processes. Linkage analysis was performed with the CRIMAP program. Significant linkage was detected for 124 loci, of which 95 were unambiguously ordered using a multipoint analysis with an average spacing of 14·2 CM. These loci were distributed among 29 linkage groups. A more comprehensive analysis including synteny group data and FISH data suggested that 26 autosomes out of 31 are covered. The complete map spans 936 CM.
© 1999 International Society for Animal Genetics
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: QAAFI Biological Information Technology (QBIT) Publications
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Created: Tue, 10 Jun 2008, 15:19:55 EST