Immunocytochemical demonstration of reduced glutathione in neurons of rat forebrain

Maybodi, Leila, Pow, David V., Kharazia, Viktor N. and Weinberg, Richard J. (1999) Immunocytochemical demonstration of reduced glutathione in neurons of rat forebrain. Brain Research, 817 1-2: 199-205. doi:10.1016/S0006-8993(98)01116-0


Author Maybodi, Leila
Pow, David V.
Kharazia, Viktor N.
Weinberg, Richard J.
Title Immunocytochemical demonstration of reduced glutathione in neurons of rat forebrain
Journal name Brain Research   Check publisher's open access policy
ISSN 0006-8993
1872-6240
Publication date 1999-01-30
Sub-type Article (original research)
DOI 10.1016/S0006-8993(98)01116-0
Volume 817
Issue 1-2
Start page 199
End page 205
Total pages 7
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 1999
Language eng
Subject C1
270107 Cell Neurochemistry
730104 Nervous system and disorders
Formatted abstract
Histochemical studies show reduced glutathione (GSH) in neuroglia, whereas immunocytochemistry of glutaraldehyde-fixed tissue reveals GSH also in neurons. Using an antibody suitable for formaldehyde-fixed tissue, we find GSH staining in the cytoplasm of neurons throughout the brain. Staining was prominent in large pyramidal neurons of cerebral cortex, in basal ganglia, and in reticular and ventrobasal thalamic nuclei.
© 1999 Elsevier Science B.V. All rights reserved.
Keyword Neurosciences
Oxidative Stress
Antibodies
Nitric Oxide
Cortex
Striatum
Thalamus
Central-nervous-system
Nitric-oxide
Histochemical-localization
Oxidized Glutathione
Parkinsons-disease
Nadph Diaphorase
Cultured Neurons
Glial-cells
Brain
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
School of Biomedical Sciences Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 8 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 10 Jun 2008, 15:09:51 EST