Non-transferrin-bound iron and cellular toxicity

Anderson, Gregory J. (1999) Non-transferrin-bound iron and cellular toxicity. Journal of Gastroenterology and Hepatology, 14 2: 105-108. doi:10.1046/j.1440-1746.1999.01828.x


Author Anderson, Gregory J.
Title Non-transferrin-bound iron and cellular toxicity
Journal name Journal of Gastroenterology and Hepatology   Check publisher's open access policy
ISSN 0815-9319
1440-1746
Publication date 1999
Sub-type Editorial
DOI 10.1046/j.1440-1746.1999.01828.x
Volume 14
Issue 2
Start page 105
End page 108
Total pages 4
Place of publication Carlton South, VIC, Australia
Publisher Blackwell Science Asia
Collection year 1999
Language eng
Subject C4
321006 Gastroenterology and Hepatology
730113 Digestive system and disorders
Formatted abstract
The role of NTBI in iron homeostasis, and particularly in iron overload conditions, remains intriguing. The difficulty in measuring low molecular weight iron complexes both in the plasma and within cells has hindered progress in the understanding of this important area of metal-induced pathogenesis. However, the application of better detection methods for NTBI (such as the method used in the McNamara et al. study) combined with recent advances in the analysis of cellular iron transport should enable the pathways of NTBI uptake, and the role of this iron fraction in tissue pathology, to be defined more precisely.
Keyword Gastroenterology & Hepatology
Molecular-weight-iron
Idiopathic Hemochromatosis
Rat-liver
Serum Iron
Clearance
Atransferrinemia
Expression
Kinetics
Plasma
Mice
Q-Index Code C4
Additional Notes Article note: "See article on page 126"

Document type: Journal Article
Sub-type: Editorial
Collection: School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 33 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 10 Jun 2008, 13:36:15 EST