Universal interventions for the primary prevention of schizophrenia

McGrath, J (2000) Universal interventions for the primary prevention of schizophrenia. Ausralian and New Zealand Journal of Psychiatry, 34 Supplement: S58-S64. doi:10.1046/j.1440-1614.2000.00783.x


Author McGrath, J
Title Universal interventions for the primary prevention of schizophrenia
Journal name Ausralian and New Zealand Journal of Psychiatry   Check publisher's open access policy
ISSN 0004-8674
Publication date 2000-01-01
Sub-type Article (original research)
DOI 10.1046/j.1440-1614.2000.00783.x
Volume 34
Issue Supplement
Start page S58
End page S64
Total pages 7
Editor Stanley V Catts
Brian I O'Toole and Daren M Draganic
Place of publication Carlton South, Vic
Publisher Blackwell Science
Collection year 2000
Language eng
Subject C1
Abstract Objective: To speculate on the role of universal (population-based) interventions designed to prevent schizophrenia. Method: A nonsystematic review of candidate risk factors for schizophrenia, with particular emphasis on the quality of the evidence, effect size of the risk factor, population attributable risk and potential for population-based intervention. Results: In order to design population-based interventions for the prevention of schizophrenia, we need to identify weak but prevalent risk factors. Based on current knowledge, the leading risk factors for schizophrenia include genes, season and place of birth, obstetric complications, prenatal exposure to viruses and prenatal nutrition. For the nongenetic exposures, we need to consider if potential interventions are effective, safe, cheap and acceptable. Conclusions: Vaccinations and interventions related to improving prenatal nutrition and antenatal care appear to be the most plausible options for universal prevention.
Keyword Psychiatry
Perinatal
Primary Prevention
Risk Factors
Schizophrenia
Universal Interventions
Bipolar Disorder
Vitamin-d
Risk
Metaanalysis
Birth
Complications
Pregnancy
Psychoses
System
Season
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 10 Jun 2008, 22:05:02 EST