Impact of diabetes on the severity of liver disease

Hickman, I.J. and Macdonald, G.A. (2007) Impact of diabetes on the severity of liver disease. The American Journal of Medicine, 120 10: 829-834. doi:10.1016/j.amjmed.2007.03.025

Author Hickman, I.J.
Macdonald, G.A.
Title Impact of diabetes on the severity of liver disease
Journal name The American Journal of Medicine   Check publisher's open access policy
ISSN 0002-9343
Publication date 2007
Year available 2007
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.amjmed.2007.03.025
Volume 120
Issue 10
Start page 829
End page 834
Total pages 6
Editor Alpert, J.S.
Place of publication United States
Publisher Excerpta Medica, Inc
Collection year 2008
Language eng
Subject C1
11 Medical and Health Sciences
Abstract The prevalence of type 2 diabetes is higher in patients who have liver diseases, such as nonalcoholic fatty liver disease, chronic viral hepatitis, hemochromatosis, alcoholic liver disease, and cirrhosis. The development of diabetes in patients with cirrhosis is well recognized, but evidence is emerging that the development of chronic liver disease and progression to cirrhosis may occur after the diagnosis of diabetes and that diabetes plays a role in the initiation and progression of liver injury. This article provides an overview of the evidence for an increased prevalence of diabetes in a range of liver diseases; the effect of diabetes on the severity of disease; the potential mechanisms whereby coexistent diabetes exacerbates progression of hepatic fibrosis; and the impact of obesity, insulin resistance, and type 2 diabetes on clinical outcomes.
Keyword Cirrhosis
Fatty liver disease
Insulin resistance
Q-Index Code C1
Q-Index Status Confirmed Code

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
2008 Higher Education Research Data Collection
UQ Diamantina Institute Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 58 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 72 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 07 May 2008, 15:15:57 EST by Kylie Hengst on behalf of UQ Diamantina Institute