Bronchoscopy and Airway Disorders in Children

Masters, Ian Brent (2008). Bronchoscopy and Airway Disorders in Children , School of Medicine, The University of Queensland.

       
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n34036575_phd_abstract.pdf n34036575_phd_abstract.pdf application/pdf 51.23KB 18
n34036575_phd_content.pdf n34036575_phd_content.pdf application/pdf 1.75MB 2
n34036575_phd_front.pdf n34036575_phd_front.pdf application/pdf 94.96KB 233
n34036575_phd_totalthesis.pdf n34036575_phd_totalthesis.pdf application/pdf 1.79MB 8
Author Masters, Ian Brent
Thesis Title Bronchoscopy and Airway Disorders in Children
School, Centre or Institute School of Medicine
Institution The University of Queensland
Publication date 2008-03
Supervisor Chang, Anne B.
Subjects 321019 Paediatrics
321018 Otorhinolaryngology
Abstract/Summary Tracheobronchial structural lesions present a considerable diagnostic challenge and workload to tertiary paediatrics. Bronchoscopy is the definitive way of confirming these diagnoses. Quantification of the size of lesions is important to the decision-making processes for management, yet this aspect of assessment has been left to subjective visual estimates of the size as there has not been a method developed that enabled quantitative measurement. The clinical profiles of children with these disorders have long been suspected to be worse than respiratory illnesses in normal children however this aspect has never been studied using objective criteria. The major hypothesis of this thesis is that structural lesions such as malacia disorders of the tracheobronchial tree result in significant respiratory morbidity that is a result of dose dependent crossectional area losses in lesions which improve with increasing age and management strategies. The aims of this thesis were i. to develop a methodology for objectively quantifing airway lesions using a paediatric bronchoscope ii. establish a cohort of children with airway lesions and quantitatively define the airway lesions and then longitudinally study these lesions and the respiratory illness profiles using validated scales of illness over a 2 year period.

 
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