A comparison of methods for assessing total arterial compliance

Haluska, B. A., Brown, J., Carlier, S. and Marwick, T. H. (2007). A comparison of methods for assessing total arterial compliance. In: Richmond, J., CSANZ 2007. 55th Annual Scientific Meeting of the Cardiac Society of Aust & NZ, Christchurch, New Zealand, (S40-S40). 9-12 August 2007.

Author Haluska, B. A.
Brown, J.
Carlier, S.
Marwick, T. H.
Title of paper A comparison of methods for assessing total arterial compliance
Conference name 55th Annual Scientific Meeting of the Cardiac Society of Aust & NZ
Conference location Christchurch, New Zealand
Conference dates 9-12 August 2007
Proceedings title CSANZ 2007   Check publisher's open access policy
Place of Publication Australia
Publisher Blackwell Publishing Asia
Publication Year 2007
ISSN 1443-9506
Editor Richmond, J.
Volume 16
Issue 2
Start page S40
End page S40
Total pages 1
Collection year 2008
Language eng
Formatted Abstract/Summary
Error condition detected Background: Reduced total arterial compliance (TAC) is associated with HTN, ischaemia and reduced exercise capacity. We compared three methods of estimating TAC in a large group of patients with and without cardiovascular risk.

Methods: We studied 320 patients (170 men; age 55 ± 10); TAC was determined by (1) the pulse-pressure method (PPM) based on the two element Windkessel, (2) the area method (AM), an integral variation of the Windkessel, and (3) the stroke volume/pulse pressure method (SVPP) a ratio of stroke volume and PP. Clinical data, risks factors and TAC by all three methods were then compared.

Results: Correlation was good between all methods: PPM/AM r = 0.83, PPM/SVPP r = 0.94 and AM/SVPP r = .80 (all p < 0.0001). Analysis of the subgroups showed significant differences between the groups for all three methods, and PPM showed the largest group differences with the smallest standard deviations (Figure). The independent correlates of patient group in linear regression models were all the same—age, HTN and TAC (all p < .0001) and the variance and model strength were all similar (F = 0.74; R2 = 0.46; p < 0.0001).

Conclusions: Normal and abnormal values of TAC vary according to method, which should be expressed. Each of the techniques shows good correlation with each other and similar values. The PPM appears to be slightly more robust in determining differences between groups with and without cardiovascular risk.
Subjects 321003 Cardiology (incl. Cardiovascular Diseases)
730106 Cardiovascular system and diseases
Q-Index Code EX

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Created: Mon, 31 Mar 2008, 11:14:34 EST by Denise Wilson on behalf of Medicine - Princess Alexandra Hospital