Broth recycling to reduce process noise resulting from concentrated substrate addition in fed-batch cultivation of Escherichaa coli

Johnston, W. A. and Cooney, M. J. (2003) Broth recycling to reduce process noise resulting from concentrated substrate addition in fed-batch cultivation of Escherichaa coli. Biotechnology Progress, 19 2: 659-661. doi:10.1021/bp025659i


Author Johnston, W. A.
Cooney, M. J.
Title Broth recycling to reduce process noise resulting from concentrated substrate addition in fed-batch cultivation of Escherichaa coli
Journal name Biotechnology Progress   Check publisher's open access policy
ISSN 8756-7938
Publication date 2003
Sub-type Article (original research)
DOI 10.1021/bp025659i
Volume 19
Issue 2
Start page 659
End page 661
Total pages 3
Place of publication Washington
Publisher American Chemical Society
Language eng
Subject 270300 Microbiology
270800 Biotechnology
Abstract In this work feed hardware for fed-batch cultivation is presented (broth recycle feed injection system or BRFIS). BRFIS proved superior to conventional submerged or dripped feed systems in reducing dissolved oxygen (DO) oscillations during Escherichia coli fed-batch cultivation (5 min coefficient of variation of 0.7% for BRFIS as compared to 26% or greater for conventional feeding hardware in a 2 L test reactor). Hence, BRFIS is useful for fed-batch cultivation systems where the DO signal is used in measurement or control.
Keyword Biotechnology & Applied Microbiology
Food Science & Technology
Cultures
Glucose
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Biomedical Sciences Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 1 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Access Statistics: 43 Abstract Views  -  Detailed Statistics
Created: Fri, 28 Mar 2008, 15:20:51 EST