Fluid Structure Interaction Modelling of a Patient Specific Cerebral Aneurysm: Effect of Hypertension and Modulus of Elasticity

Ahmed, S., Šutalo, I. D., Kavnoudias, H. and Madan, A. (2007). Fluid Structure Interaction Modelling of a Patient Specific Cerebral Aneurysm: Effect of Hypertension and Modulus of Elasticity. In: Peter Jacobs, Tim McIntyre, Matthew Cleary, David Buttsworth, David Mee, Rose Clements, Richard Morgan and Charles Lemckert, 16th Australasian Fluid Mechanics Conference (AFMC). 16th Australasian Fluid Mechanics Conference (AFMC), Gold Coast, Queensland, Australia, (75-81). 3-7 December, 2007.

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Author Ahmed, S.
Šutalo, I. D.
Kavnoudias, H.
Madan, A.
Title of paper Fluid Structure Interaction Modelling of a Patient Specific Cerebral Aneurysm: Effect of Hypertension and Modulus of Elasticity
Conference name 16th Australasian Fluid Mechanics Conference (AFMC)
Conference location Gold Coast, Queensland, Australia
Conference dates 3-7 December, 2007
Proceedings title 16th Australasian Fluid Mechanics Conference (AFMC)
Place of Publication Brisbane, Australia
Publisher School of Engineering, The University of Queensland
Publication Year 2007
Year available 2007
Sub-type Fully published paper
ISBN 978-1-864998-94-8
Editor Peter Jacobs
Tim McIntyre
Matthew Cleary
David Buttsworth
David Mee
Rose Clements
Richard Morgan
Charles Lemckert
Start page 75
End page 81
Total pages 7
Collection year 2007
Language eng
Abstract/Summary This study investigates the computational coupled Fluid Structure Interaction (FSI) of a large wide neck cerebral aneurysm where the elastic aneurysm wall has non-linear deformation. A patient specific cerebral aneurysm geometry was obtained from CT medical scans. Computational Fluid Dynamics (CFD) was used to model the three-dimensional transient incompressible laminar non-Newtonian fluid flow through the aneurysm. For the structural analysis the aneurysm wall was assumed to be isotropic, incompressible and homogeneous. The effect of hypertension and modulus of elasticity were analysed in terms of fluid flow, wall shear stress, deformation and effective (Von- Mises) stress. The predictions showed the areas of the aneurysm that experience high stress and deformation. The aneurysm with hypertensive blood pressure (HBP) had higher stress and deformation compared to the normotensive blood pressure (NBP). The maximum deformation of the aneurysm wall increased with decrease in the wall modulus of elasticity. For a value of the Young’s Modulus=25 MPa, the maximum deformation and effective stress increased rapidly due to the lateral movement of the aneurysm. Thus higher blood pressure as well as lower modulus of elasticity are important factors for the rapid aneurysm growth and rupture.
Subjects 240000 Physical Sciences
Keyword Fluid Structure Interaction (FSI)
cerebral aneurysm
elastic aneurysm wall
Computational Fluid Dynamics (CFD)
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Conference Paper
Collection: 16th Australasian Fluid Mechanics Conference
 
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Created: Fri, 14 Mar 2008, 08:23:54 EST by Thelma Whitbourne on behalf of School of Engineering