Resting energy expenditure in children with inflammatory bowel disease

Hill, R. J., Cleghorn, G. J., Withers, G. D., Lewindon, P. J., Ee, L. C., Connor, F. and Davies, P. S. W. (2007) Resting energy expenditure in children with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition, 45 3: 342-346. doi:10.1097/MPG.0b013e31804a85f2


Author Hill, R. J.
Cleghorn, G. J.
Withers, G. D.
Lewindon, P. J.
Ee, L. C.
Connor, F.
Davies, P. S. W.
Title Resting energy expenditure in children with inflammatory bowel disease
Journal name Journal of Pediatric Gastroenterology and Nutrition   Check publisher's open access policy
ISSN 0277-2116
Publication date 2007-09
Sub-type Article (original research)
DOI 10.1097/MPG.0b013e31804a85f2
Volume 45
Issue 3
Start page 342
End page 346
Total pages 5
Place of publication Philadelphia
Publisher Lippincott Williams & Wilkins
Collection year 2008
Language eng
Subject 730204 Child health
321006 Gastroenterology and Hepatology
Formatted abstract
OBJECTIVES:
There is controversy in the literature regarding the effect of inflammatory bowel disease (IBD) on resting energy expenditure (REE). In many cases this may have resulted from inappropriate adjustment of REE measurements to account for differences in body composition. This article considers how to appropriately adjust measurements of REE for differences in body composition between individuals with IBD.

PATIENTS AND METHODS:
Body composition, assessed via total body potassium to yield a measure of body cell mass (BCM), and REE measurements were performed in 41 children with Crohn disease and ulcerative colitis in the Royal Children's Hospital, Brisbane, Australia. Log-log regression was used to determine the power function to which BCM should be raised to appropriately adjust REE to account for differences in body composition between children.

RESULTS:

The appropriate value to "adjust" BCM was found to be 0.49, with a standard error of 0.10.

CONCLUSIONS:

Clearly, there is a need to adjust for differences in body composition, or at the very least body weight, in metabolic studies in children with IBD. We suggest that raising BCM to the power of 0.5 is both a numerically convenient and a statistically valid way of achieving this aim. Under circumstances in which the measurement of BCM is not available, raising body weight to the power of 0.5 remains appropriate. The important issue of whether REE is changed in cases of IBD can then be appropriately addressed.
Keyword Adolescent
Basal Metabolism/*physiology
Body Composition
Body Weight/physiology
Child
Energy Metabolism/*physiology
Female
Humans
Inflammatory Bowel Diseases/*metabolism
Male
Mathematics
Nutritional Requirements
Nutritional Status
Potassium Radioisotopes/analysis
Regression Analysis
Q-Index Code C1
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
2008 Higher Education Research Data Collection
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 12 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 07 Mar 2008, 10:14:04 EST