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Abnormalities of left atrial function after cardioversion: an atrial strain rate study
Thomas, L., Mckay, T., Byth, K. and Marwick, T. H. (2007) Abnormalities of left atrial function after cardioversion: an atrial strain rate study. Heart, 93 1: 89-95.
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| Author(s) |
Thomas, L.
Mckay, T.
Byth, K.
Marwick, T. H.
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| Title |
Abnormalities of left atrial function after cardioversion: an atrial strain rate study
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| Journal name |
Heart
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| Publication date |
2007
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| Year available |
2006
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| Volume number |
93
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| Issue number |
1
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| ISSN |
1355-6037
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| Start page |
89
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| End page |
95
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| Total pages |
7
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| Editor(s) |
Hall, R.J.
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| Place of publication |
U.K.
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| Publisher |
B.M.J. Publishing Group
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| Collection year |
2008
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| Subject |
C1
321003 Cardiology (incl. Cardiovascular Diseases)
730106 Cardiovascular system and diseases
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| Abstract |
Background and objectives: The role of atrial myocardial dysfunction after cardioversion is unclear. In a comparison of patients after successful cardioversion from chronic atrial
fibrillation ( CAF) and normal controls, we sought to determine whether Doppler-derived atrial strain rate ( A-sr) could be used to measure global left atrial function and whether A-sr was reduced
in patients with CAF. Methods: A-sr was measured from the basal septal, lateral, inferior and anterior atrial walls from the apical four-chamber and two-chamber views in 37 patients with CAF who
had been cardioverted to sinus rhythm and followed up for 6 months, and in a cohort of 37 healthy people. Conventional measures of atrial function included peak transmitral A-wave velocity, A-wave
velocity time integral, atrial fraction and the left atrial ejection fraction. Doppler tissue imaging was used to estimate atrial contraction velocity ( A' velocity). In addition to amplitude
parameters, the time to peak A-sr was measured from aortic valve closure. Results: Immediately after cardioversion, A-sr in the CAF cohort ( baseline) was significantly lower than in controls (
mean ( SD) -0.53 ( 0.31) v -1.6 ( 0.75) s(-1); p < 0.001); the A-sr correlated with A' velocity ( r = 0.63; p < 0.001) in patients. Atrial function improved over time, with maximal change
observed in the initial 4 weeks after cardioversion. The time to peak A-sr was increased in the CAF group compared with controls ( 0.55 ( 0.15) v 0.46 ( 0.12) s), but this failed to normalise over
time. Conclusion: A-sr is a descriptor of atrial function, which is reduced after cardioversion from CAF and subsequently recovers.
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| Keyword(s) |
Cardiac & Cardiovascular Systems
Regional Myocardial-function
Sinus Rhythm
Fibrillation
Echocardiography
Conversion
Contraction
Dysfunction
Ablation
Ischemia
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| Additional Notes |
2007 HERDC eligible - expanded publication year
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