A correlative study of ultrasound with serology in an area in China co-endemic for human alveolar and cystic echinococcosis

Yang, Y. R., Craig, P. S., Ito, A., Vuitton, D. A., Giraudoux, P., Sun, T., Williams, G. M., Huang, Z., Li, Z., Wang, Y., Teng, J., Li, Y., Huang, L., Wen, H., Jones, Malcolm K. and McManus, D. P. (2007) A correlative study of ultrasound with serology in an area in China co-endemic for human alveolar and cystic echinococcosis. Tropical Medicine and International Health, 12 5: 637-646. doi:10.1111/j.1365-3156.2007.01834.x


Author Yang, Y. R.
Craig, P. S.
Ito, A.
Vuitton, D. A.
Giraudoux, P.
Sun, T.
Williams, G. M.
Huang, Z.
Li, Z.
Wang, Y.
Teng, J.
Li, Y.
Huang, L.
Wen, H.
Jones, Malcolm K.
McManus, D. P.
Title A correlative study of ultrasound with serology in an area in China co-endemic for human alveolar and cystic echinococcosis
Journal name Tropical Medicine and International Health   Check publisher's open access policy
ISSN 1360-2276
1365-3156
Publication date 2007-05
Sub-type Article (original research)
DOI 10.1111/j.1365-3156.2007.01834.x
Volume 12
Issue 5
Start page 637
End page 646
Total pages 10
Editor S. Groener
Place of publication Oxford, United Kingdom
Publisher Blackwell Publishing
Collection year 2008
Language eng
Subject C1
320299 Immunology not elsewhere classified
730199 Clinical health not specific to particular organs, diseases and conditions
Formatted abstract
We correlated ultrasound (US) imaging classifications for human alveolar echinococcosis (AE) and cystic echinococcosis (CE) with serology (ELISA and immunoblotting (IB) incorporating native and recombinant/purified echinococcal antigens) in community surveys (2001–2003) and follow-up (2002 and 2003) of US-confirmed cases in Ningxia, China. One hundred and seventy-one cases (96 with AE, 75 with CE) were identified; of these, US classification and serological data were obtained for 142 and 112 cases, respectively. Seropositive-rates increased in CE patients with highly viable unilocular cyst lesions (Types CL, CE 1 or CE 2) to degenerating primary lesions (CE 3), but then decreased in subjects with inactive (CE 4) or dead (CE 5) cysts. In contrast, there was a constant increase in seropositivity from the early (P1, P2) to the advanced stages (P3, P4) with AE cases. For US-confirmed cases, follow-up by US combined with serology is invaluable for studying the clinical progression of echinococcosis and for detecting recurrent cysts or reinfection post-treatment.
Keyword Public, Environmental & Occupational Health
Tropical Medicine
alveolar echinococcosis
cystic echinococcosis
ultrasound
serology
Ningxia Hui Autonomous Region of China
Hui Autonomous Region
Hydatid-disease
Southwestern Germany
Community Surveys
Recombinant Em18
E-multilocularis
Public-health
Antigen-b
Follow-up
Granulosus
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published Online: 19 Mar 2007 Abstract available in Spanish.

 
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Created: Mon, 18 Feb 2008, 16:51:53 EST