High frequency distortion product otoacoustic emissions in children with and without middle ear dysfunction

Kei, J., Brazel, B., Crebbin, K., Richards, A. and Willeston, N. (2007) High frequency distortion product otoacoustic emissions in children with and without middle ear dysfunction. International Journal of Pediatric Otorhinolaryngology, 71 1: 125-133. doi:10.1016/j.ijporl.2006.09.013

Author Kei, J.
Brazel, B.
Crebbin, K.
Richards, A.
Willeston, N.
Title High frequency distortion product otoacoustic emissions in children with and without middle ear dysfunction
Journal name International Journal of Pediatric Otorhinolaryngology   Check publisher's open access policy
ISSN 0165-5876
Publication date 2007
Sub-type Article (original research)
DOI 10.1016/j.ijporl.2006.09.013
Volume 71
Issue 1
Start page 125
End page 133
Total pages 9
Editor R. J. Ruben
Place of publication United Kingdom
Publisher Elsevier Ireland Ltd
Collection year 2008
Language eng
Subject 321025 Rehabilitation and Therapy - Hearing and Speech
730204 Child health
750312 Youth/child development and welfare
730111 Hearing, vision, speech and their disorders
Abstract Objective: Distortion product otoacoustic emissions (DPOAEs) (9-16 kHz) area useful measure of the function of the cochlea, which may be damaged by ototoxic drugs during anticancer chemotherapy. As children undergoing chemotherapy may also have middle ear problems, it is necessary to know if middle ear problems would have a confounding effect on the ability of DPOAEs to assess cochlear function in the extend high frequency region (9-16 kHz). The present study aimed to investigate the effect of middle ear dysfunction on DPOAEs in the extended high frequency region in young children. Methods: The sample was comprised of 100 ears of 50 school-aged children (21 boys and 29 girls) with a mean age of 6.3 years (S.D. = 0.5; range 5.3-7.3). Otoscopy, pure tone hearing screening, tympanometry, acoustic reflexes and DPOAEs for both the conventional and extended high frequencies were administered to each child under typical school screening conditions. Participants were classified into one of three groups based on immittance (tympanometry and acoustic reflex) results. They included a "pass immittance" group, a "fail immittance" group and an "undetermined" group (with a pass in either tympanometry or acoustic reflexes, but not both). DPOAE amplitudes and signal-to-noise ratios (SNRs) were measured and compared across the three groups of participants. Results: The fail immittance group showed significantly smaller DPOAE amplitudes and SNRs when compared to the other two groups at frequencies ranging from 1 to 9.5 kHz and at 13 kHz, but not at 10, 11, 12 and 14 kHz. There was no significant difference in DPOAE results between the pass immittance and undetermined groups. Conclusions: Despite the adverse effects of middle ear dysfunction, its effect on DPOAEs in the extended high frequency region was not as severe as that in the lower frequency region. Hence, assessment of cochlear function in children with a middle ear lesion in the extended high frequencies using DPOAEs should be made with caution. Crown Copyright (C) 2006 Published by Elsevier Ireland Ltd. All rights reserved.
Keyword Otorhinolaryngology
otoacoustic emissions
distortion products
otitis media
middle ear
middle ear dysfunction
Q-Index Code C1

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Created: Mon, 18 Feb 2008, 16:05:26 EST