Nanomechanics of microtubules

Kis, A, Kasas, S, Babic, B, Kulik, AJ, Benoit, W, Briggs, GAD, Schonenberger, C, Catsicas, S and Forro, L (2002) Nanomechanics of microtubules. Physical Review Letters, 89 24: . doi:10.1103/PhysRevLett.89.248101

Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
UQ122510.pdf Full text (open access) application/pdf 287.76KB 61

Author Kis, A
Kasas, S
Babic, B
Kulik, AJ
Benoit, W
Briggs, GAD
Schonenberger, C
Catsicas, S
Forro, L
Title Nanomechanics of microtubules
Journal name Physical Review Letters   Check publisher's open access policy
ISSN 0031-9007
Publication date 2002
Sub-type Article (original research)
DOI 10.1103/PhysRevLett.89.248101
Open Access Status File (Publisher version)
Volume 89
Issue 24
Total pages 4
Place of publication College Pk
Publisher American Physical Soc
Language eng
Abstract We have determined the mechanical anisotropy of a single microtubule by simultaneously measuring the Young's and the shear moduli in vitro. This was achieved by elastically deforming the microtubule deposited on a substrate tailored by electron-beam lithography with a tip of an atomic force microscope. The shear modulus is 2 orders of magnitude lower than the Young's, giving rise to a length-dependent flexural rigidity of microtubules. The temperature dependence of the microtubule's bending stiffness in the (5-40) degreesC range shows a strong variation upon cooling coming from the increasing interaction between the protofilaments.
Keyword Physics, Multidisciplinary
Force Microscopy
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 199 times in Thomson Reuters Web of Science Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 25 Jan 2008, 15:48:02 EST