Metagenomic analysis of phosphorus removing sludge communities

Martín, Héctor García, Kunin, Victor, Ivanova, Natalia, Warnecke, Falk, Peterson, S. B., Barry, Kerrie, McHardy, Alice C., Yeates, Christine, He, Shaomei, Salamov, Asaf, Szeto, Ernest, Dalin, Eileen, Putnam, Nik, Rigoutsos, Isidore, Kyrpides, Nikos C., Blackall, Linda Louise, McMahon, Katherine D. and Hugenholtz, Philip (2006). Metagenomic analysis of phosphorus removing sludge communities. In: ISME Vienna 2006: 11th International Symposium on Microbial Ecology. The hidden powers: Microbial communities in action, Vienna, Austria, (A457-A457). 20-25 August 2006.

Author Martín, Héctor García
Kunin, Victor
Ivanova, Natalia
Warnecke, Falk
Peterson, S. B.
Barry, Kerrie
McHardy, Alice C.
Yeates, Christine
He, Shaomei
Salamov, Asaf
Szeto, Ernest
Dalin, Eileen
Putnam, Nik
Rigoutsos, Isidore
Kyrpides, Nikos C.
Blackall, Linda Louise
McMahon, Katherine D.
Hugenholtz, Philip
Title of paper Metagenomic analysis of phosphorus removing sludge communities
Conference name ISME Vienna 2006: 11th International Symposium on Microbial Ecology. The hidden powers: Microbial communities in action
Conference location Vienna, Austria
Conference dates 20-25 August 2006
Convener International Society for Microbial Ecology
Publisher Kenes International
Publication Year 2006
Sub-type Poster
Start page A457
End page A457
Collection year 2006
Language eng
Formatted Abstract/Summary
Enhanced Biological Phosphorus Removal (EBPR) is not well understood at the metabolic level despite being one of the best-studied microbially-mediated industrial processes due to its ecological and economic relevance. Here we present a metagenomic analysis of two lab-scale EBPR sludges dominated by the uncultured bacterium, “Candidatus Accumulibacter phosphatis”. This analysis sheds light on several controversies in EBPR metabolic models and provides hypotheses explaining the dominance of A. phosphatis in this habitat, its lifestyle outside EBPR and probable cultivation requirements. Comparison of the same species from different EBPR sludges highlights recent evolutionary dynamics in the A. phosphatis genome that could be linked to mechanisms for environmental adaptation. In spite of an apparent lack of phylogenetic overlap in the flanking communities of the two sludges studied, common functional themes were found, at least one of them complementary to the inferred metabolism of the dominant organism. The present study provides a much-needed blueprint for a systems-level understanding of EBPR and illustrates that metagenomics enables detailed, often novel, insights into even well-studied biological systems.
Subjects EX
270399 Microbiology not elsewhere classified
780199 Other
Q-Index Code EX
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Presented during Poster Session 3.

Document type: Conference Paper
Collection: Advanced Water Management Centre Publications
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Created: Thu, 23 Aug 2007, 22:32:07 EST