Evolving discriminative motifs for recognizing proteins imported to the peroxisome via the PTS2 pathway

Boden, M. B. and Hawkins, J. C. (2006). Evolving discriminative motifs for recognizing proteins imported to the peroxisome via the PTS2 pathway. In: G.G Yen, 2006 IEEE Congress on Evolutionary Computation. 2006 IEEE Congress on Evolutionary Computation, Vancouver, BC, Canada, (2750-2755). 16-21 July, 2006.

Author Boden, M. B.
Hawkins, J. C.
Title of paper Evolving discriminative motifs for recognizing proteins imported to the peroxisome via the PTS2 pathway
Conference name 2006 IEEE Congress on Evolutionary Computation
Conference location Vancouver, BC, Canada
Conference dates 16-21 July, 2006
Proceedings title 2006 IEEE Congress on Evolutionary Computation
Journal name 2006 Ieee Congress On Evolutionary Computation, Vols 1-6
Place of Publication Piscataway, N.J., USA
Publisher IEEE
Publication Year 2006
Sub-type Fully published paper
ISBN 9780780394872
0780394879
Editor G.G Yen
Volume 1
Issue 1
Start page 2750
End page 2755
Total pages 6
Collection year 2006
Language eng
Abstract/Summary Peroxisomes are small subcellular compartments that utilize proteins manufactured in the cytoplasm. Proteins use one of two peroxisomal import pathways. This paper presents a simple evolutionary search for a motif that describes the signal used by one of the two pathways: PTS2. The evolved motif has a discriminative accuracy exceeding previously manually curated motifs and can be used to screen genomic data for putative peroxisomal proteins.
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Article # 1688653

 
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Created: Thu, 23 Aug 2007, 21:54:22 EST