Accuracy of strain rate techniques for ientification of viability at dobutamine stress echo: A follow-up study after revascularization

Hanekom, L., Jenkins, C., Short, L. and Marwick, T. H. (2004). Accuracy of strain rate techniques for ientification of viability at dobutamine stress echo: A follow-up study after revascularization. In: Dr A.N. DeMaria, Journal of the American College of Cardiology. 53rd Annual Scientific Session of the American College of Cardiology, New Orleans, (360A-360A). 7-10 March 2004.


Author Hanekom, L.
Jenkins, C.
Short, L.
Marwick, T. H.
Title of paper Accuracy of strain rate techniques for ientification of viability at dobutamine stress echo: A follow-up study after revascularization
Conference name 53rd Annual Scientific Session of the American College of Cardiology
Conference location New Orleans
Conference dates 7-10 March 2004
Proceedings title Journal of the American College of Cardiology   Check publisher's open access policy
Place of Publication USA
Publisher Elsevier Inc
Publication Year 2004
DOI 10.1016/S0735-1097(04)91523-9
ISSN 0735-1097
Editor Dr A.N. DeMaria
Volume 43
Issue 5
Start page 360A
End page 360A
Total pages 1
Language eng
Abstract/Summary Background. Myocardial viability (VM) assessment based on wall motion scoring (WMS) with dobutamine echo (DbE) is difficult and subjective. New quantitative techniques such as strain rate imaging (SRI) correspond with isotopic techniques but their ability to predict functional recovery (FR) after revascularization is unclear. Methods. Stable post-MI pts (n=43, age 63±9, EF 36±6%) underwent SRI during DbE. WMS evidence of VM was based on lowdose augmentation at DbE. SR, end-systolic strain (ESS), post-systolic strain (PSS) and timing were analyzed at rest and low dose in abnormal segts. Pts were followed for 9±12 months; FR was defined as segt improvement on post-revascularization images. Results: Of 180 segts with abnormal resting function, 83 showed FR and 97 did not. Resting parameters were not predictive of recovery; resting post-systolic shortening had a sensitivity and specificity <50%. Viable vs nonviable segts showed differences in lowdose SR (0.9±0.6 vs 0.4±0.5/s, p<0.001, optimal cutoff >0.6), SR increment (0.5±0.5 vs 0.1±0.6/s, p<0.001, cutoff >0.23), ESS (11.6±9.2 vs 4.7±9.3, p<0.001, cutoff >8.5), ESS increment (4.9±9.9 vs 0.7±6.2, p<0.001, cutoff >3.4) and time to ES (0.31±0.9 vs 0.38±0.09, p<0.001, cutoff <0.32). Sensitivity and specificity of quantitative parameters were comparable to WM analysis (Table). Conclusions. SR and strain responses to DbE are a feasible marker of viability, comparable to WM assessment.
Subjects EX
730106 Cardiovascular system and diseases
321003 Cardiology (incl. Cardiovascular Diseases)
110201 Cardiology (incl. Cardiovascular Diseases)
Keyword Cardiac & Cardiovascular Systems
Q-Index Code EX

 
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