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Lim, Yun-An, Rhein, Virginie, Baysang, Ginette, Meier, Fides, Poljak, Anne, Raftery, Mark J., Guilhaus, Michael, Ittner, Lars M., Eckert, Anne and Gotz, Jürgen (2010) Aβ and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics, 10 8: 1621-1633. doi:10.1002/pmic.200900651 8   44 Cited 45 times in Scopus45 0
Pennanen L., Welzl H., D'Adamo P., Nitsch R.M. and Gotz J. (2004) Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice. Neurobiology of Disease, 15 3: 500-509. doi:10.1016/j.nbd.2003.11.020 12   49 Cited 53 times in Scopus53 0
Kins, S, Kurosinski, P, Nitsch, RM and Gotz, J (2003) Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice. American Journal of Pathology, 163 3: 833-843. doi:10.1016/S0002-9440(10)63444-X 22   93 0
Koehler, Christoph, Dinekov, Maja and Goetz, Juergen (2013) Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice. Neurobiology of Aging, 34 5: 1369-1379. doi:10.1016/j.neurobiolaging.2012.11.010 73   4 Cited 6 times in Scopus6 0
Kulic L., Kurosinski P., Chen F., Tracy J., Mohajeri M.H., Li H., Nitsch R.M. and Gotz J. (2006) Active immunization trial in Aβ42-injected P301L tau transgenic mice. Neurobiology of Disease, 22 1: 50-56. doi:10.1016/j.nbd.2005.10.002 18   10 Cited 16 times in Scopus16 0
Gotz J., Deters N., Doldissen A., Bokhari L., Ke Y., Wiesner A., Schonrock N. and Ittner L.M. (2007). A decade of tau transgenic animal models and beyond. In: , , (91-103). . doi:10.1111/j.1750-3639.2007.00051.x 15   64 Cited 94 times in Scopus94 0
Chew, Yee Lian, Fan, Xiaochen, Goetz, Juergen and Nicholas, Hannah R. (2013) Aging in the nervous system of Caenorhabditis elegans. Communicative and Integrative Biology, 6 5: e25288.1-e25288.6. doi:10.4161/cib.25288 42   Cited 0 times in Scopus0 0
Schild A., Schmidt K., Lim Y.-A., Ke Y., Ittner L.M., Hemmings B.A. and Gotz J. (2006) Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation. International Journal of Developmental Neuroscience, 24 7: 437-443. doi:10.1016/j.ijdevneu.2006.08.005 16   11 Cited 7 times in Scopus7 0
Rhein, Virginie, Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Droese, Stefan, Brandt, Ulrich, Mueller-Spahn, Franz, Czech, Christian, Goetz, Jurgen and Eckert, Anne (2008). Altered mitochondrial respiration and energy metabolism in brain cells from transgenic Alzheimer's disease mice. In: Biochimica Et Biophysica Acta-Bioenergetics. 15th European Bioenergetic Conference, Dublin Ireland, (S85-S86). Jul 19-24, 2008. doi:10.1016/j.bbabio.2008.05.335 12   0 0
Hundelt, M., Fath, T., Selle, K., Oesterwind, K., Jordan, J., Schultz, C., Götz, J., von Engelhardt, J., Monyer, H., Lewejohann, L., Sachser, N., Bakota, L. and Brandt, R. (2011) Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation. Neurobiology of Aging, 32 6: 991-1006. doi:10.1016/j.neurobiolaging.2009.06.007 19   6 Cited 6 times in Scopus6 0
Schild A., Ittner L.M. and Gotz J. (2006) Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice. Biochemical and Biophysical Research Communications, 343 4: 1171-1178. doi:10.1016/j.bbrc.2006.03.066 14   22 Cited 23 times in Scopus23 0
Liang, Vanessa, Ullrich, Milena, Lam, Hong, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Kassiou, Michael, Gotz, Jürgen and Nicholas, Hannah R. (2014) Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome. Cellular and Molecular Life Sciences, 71 17: 3339-3361. doi:10.1007/s00018-014-1558-7 14   2 Cited 2 times in Scopus2 23
Kurosinski, P, Guggisberg, M and Gotz, J (2002) Alzheimer's and Parkinson's disease - overlapping or synergistic pathologies?. Trends in Molecular Medicine, 8 1: 3-5. doi:10.1016/S1471-4914(01)02246-8 25   54 Cited 34 times in Scopus34 0
Goetz, Juergen, Ittner, Lars M. and Schonrock, Nicole (2006) Alzheimer's disease and frontotemporal dementia: prospects of a tailored therapy?. Medical Journal of Australia, 185 7: 381-384. 14   18
Goetz, Juergen, Matamales, Miriam, Goetz, Naeman N., Ittner, Lars M. and Eckert, Anne (2012) Alzheimer's disease models and functional genomics-how many needles are there in the haystack?. Frontiers in Physiology, 3 320: 320.1-320.14. doi:10.3389/fphys.2012.00320 56   Cited 2 times in Scopus2 3
Grimm, Amandine, Lim, Yun-An, Mensah-Nyagan, Ayikoe Guy, Goetz, Jurgen and Eckert, Anne (2012) Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship. Molecular Neurobiology, 46 1: 151-160. doi:10.1007/s12035-012-8281-x 40   7 Cited 9 times in Scopus9 0
Gotz, Jurgen, Schonrock, Nicole, Vissel, Bryce and Ittner, Lars M. (2009) Alzheimer's disease selective vulnerability and modeling in transgenic Mice. Journal of Alzheimer's Disease, 18 2: 243-251. doi:10.3233/JAD-2009-1143 15   14 Cited 14 times in Scopus14 0
Ittner, Lars M. and Gotz, Jürgen (2011) Amyloid-β and tau - A toxic pas de deux in Alzheimer's disease. Nature Reviews Neuroscience, 12 2: 67-72. doi:10.1038/nrn2967 17   231 Cited 215 times in Scopus215 0
Rhein, Virginie, Song, Xiaomin, Wiesner, Andreas, Ittner, Lars M., Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Drose, Stefan, Brandt, Ulrich, Savaskan, Egemen, Czech, Christian, Gotz, Jurgen and Eckert, Anne (2009) Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America, 106 47: 20057-20062. doi:10.1073/pnas.0905529106 18   179 Cited 189 times in Scopus189 1
Gotz, J, Chen, F, Ferrari, A, Kurosinski, P, Schild, A, Nitsch, RM and van Dorpe, J (2002). Amyloid-induced neurofibrillary tangle formation. In: Neurobiology of Aging. , , (S567-S567). . 14   0
Pennanen, L, David, D, Hoerndli, F, Kurosinski, P, Chen, F, Schild, A, Ferrari, A, Nitsch, RM and Gotz, J (2004). Amyloid-induced neurofibrillary tangle formation addressed in vivo and in vitro. In: Neurobiology of Aging. 9th International Conference on Alzheimers Disease and Related Disorders, Philadelphia Pa, (S255-S255). Jul 17-22, 2004. doi:10.1016/S0197-4580(04)80857-1 15   0 0
Gotz J., Schild A., Hoerndli F. and Pennanen L. (2004) Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: Insight from transgenic mouse and tissue-culture models. International Journal of Developmental Neuroscience, 22 7: 453-465. doi:10.1016/j.ijdevneu.2004.07.013 23   61 Cited 72 times in Scopus72 0
Ferrari A., Hoerndli F., Baechi T., Nitsch R.M. and Gotz J. (2003) β-amyloid induces paired helical filament-like tau filaments in tissue culture. Journal of Biological Chemistry, 278 41: 40162-40168. doi:10.1074/jbc.M308243200 18   109 Cited 117 times in Scopus117 0
David D.C., Ittner L.M., Gehrig P., Nergenau D., Shepherd C., Halliday G. and Gotz J. (2006) β-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes. Proteomics, 6 24: 6566-6577. doi:10.1002/pmic.200600634 13   49 Cited 52 times in Scopus52 0
Kohler, C., Bista, P., Gotz, J. and Schroder, H. (2010) Analysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathy. Brain Research, 1347 111-124. doi:10.1016/j.brainres.2010.05.076 18   4 Cited 4 times in Scopus4 0
Gotz, Jurgen and Ittner, Lars M. (2008) Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience, 9 7: 532-544. doi:10.1038/nrn2420 30   243 Cited 278 times in Scopus278 0
Gotz, Jurgen, Gladbach, Amadeus, Pennanen, Luis, van Eersel, Janet, Schild, Andreas, David, Della and Ittner, Lars M. (2010) Animal models reveal role for tau phosphorylation in human disease. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1802 10: 860-871. doi:10.1016/j.bbadis.2009.09.008 18   25 Cited 24 times in Scopus24 0
Baur, Karen, Rauer, Mathias, Richter, Kirsten, Pagenstecher, Axel, Gotz, Jurgen, Hausmann, Jurgen and Staeheli, Peter (2008) Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes. Journal of Virology, 82 6: 3099-3108. doi:10.1128/JVI.02479-07 16   5 Cited 6 times in Scopus6 0
Götz, Jurgen, Ittner, Lars M, Schonrock, Nicole and Cappai, Roberto (2008) An update on the toxicity of A-beta in Alzheimer's disease. Neuropsychiatric Disease and Treatment, 4 6: 1033-1042. doi:10.2147/NDT.S3016 14   Cited 21 times in Scopus21 0
Hoerndli F.J., Pelech S., Papassotiropoulos A. and Gotz J. (2007) Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. European Journal of Neuroscience, 26 1: 60-72. doi:10.1111/j.1460-9568.2007.05618.x 15   20 Cited 21 times in Scopus21 0
Goetz, J. and Ittner, L. M. (2009). Axonal transport in tau transgenic mouse models. In: Journal of Neurochemistry. 4th European-Society-for-Neurochemistry Conference on Advances in Molecular Mechanisms of Neurological Disorders, Leipzig Germany, (59-59). Jul 11-14, 2009. 12   0
Probst, A, Gotz, J, Wiederhold, KH, Tolnay, M, Mistl, C, Jaton, AL, Hong, M, Ishihara, T, Lee, VMY, Trojanowski, JQ, Jakes, R, Crowther, RA, Spillantini, MG, Burki, K and Goedert, M (2000) Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathologica, 99 5: 469-481. 16   206
Ullrich, Milena, Liang, Vanessa, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Lam, Hong, Berber, Slavica, Kassiou, Michael, Nicholas, Hannah R. and Goetz, Juergen (2014) Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans. Nature Protocols, 9 9: 2237-2255. doi:10.1038/nprot.2014.150 15   1 Cited 0 times in Scopus0 23
Ittner, Arne, Ke, Yazi D., van Eersel, Janet, Gladbach, Amadeus, Gotz, Jurgen and Ittner, Lars M. (2011) Brief update on different roles of tau in neurodegeneration. IUBMB Life, 63 7: 495-502. doi:10.1002/iub.467 11   12 Cited 16 times in Scopus16 0
Gotz, J and Nitsch, RM (2001) Compartmentalized tau hyperphosphorylation and increased levels of kinases in transgenic mice. Neuroreport, 12 9: 2007-2016. 14   31
Frost, Bess, Gotz, Jurgen and Feany, Mel B. (2015) Connecting the dots between tau dysfunction and neurodegeneration. Trends in Cell Biology, 25 1: 46-53. doi:10.1016/j.tcb.2014.07.005 13   Cited 1 times in Scopus1 3
Eckert, Anne, Schulz, Kathrin L., Rhein, Virginie and Gotz, Jürgen (2010) Convergence of amyloid-β and tau pathologies on mitochondria in vivo. Molecular Neurobiology, 41 2-3: 107-114. doi:10.1007/s12035-010-8109-5 18   42 Cited 47 times in Scopus47 0
van Eersel, Janet, Ke, Yazi D., Gladbach, Amadeus, Bi, Mian, Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2011) Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons. PLoS ONE, 6 7: e22850.1-e22850.13. doi:10.1371/journal.pone.0022850 9   19 Cited 19 times in Scopus19 1
Schonrock, Nicole and Goetz, Juergen (2012) Decoding the non-coding RNAs in Alzheimer's disease. Cellular and Molecular Life Sciences, 69 21: 3543-3559. doi:10.1007/s00018-012-1125-z 31   20 Cited 20 times in Scopus20 0
Gotz J., Probst A., Ehler E., Hemmings B. and Kues W. (1998) Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Cα. National Academy of Sciences. Proceedings, 95 21: 12370-12375. doi:10.1073/pnas.95.21.12370 22   136 Cited 136 times in Scopus136 0
Ittner, Lars M., Ke, Yazi D., Delerue, Fabien, Bi, Mian, Gladbach, Amadeus, van Eersel, Janet, Wolfing, Heidrun, Chieng, Billy C., Christie, MacDonald J., Napier, Ian A., Eckert, Anne, Staufenbiel, Matthias, Hardeman, Edna and Gotz, Jurgen (2010) Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models. Cell, 142 3: 387-397. doi:10.1016/j.cell.2010.06.036 18   346 Cited 382 times in Scopus382 1
Cho, Kwy, Goetz, J, Wright, Cve, Fritz, A, Hardwicke, J and Derobertis, EM (1988) Differential Utilization of the Same Reading Frame in a Xenopus Homeobox Gene Encodes 2 Related Proteins Sharing the Same Dna-Binding Specificity. Embo Journal, 7 7: 2139-2149. 8   124
Pennanen L. and Gotz J. (2005) Different tau epitopes define Aβ42-mediated tau insolubility. Biochemical and Biophysical Research Communications, 337 4: 1097-1101. doi:10.1016/j.bbrc.2005.09.168 9   19 Cited 22 times in Scopus22 0
Habicht G., Haupt C., Friedrich R.P., Hortschansky P., Sachse C., Meinhardt J., Wieligmann K., Gellermann G.P., Brodhun M., Gotz J., Halbhuber K.-J., Rocken C., Horn U. and Fandrich M. (2007) Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils. Proceedings of the National Academy of Sciences of the United States of America, 104 49: 19232-19237. doi:10.1073/pnas.0703793104 9   120 Cited 124 times in Scopus124 0
Gotz, Jurgen, Lim, Yun-An, Ke, Yazi D., Eckert, Anne and Ittner, Lars M. (2010) Dissecting Toxicity of Tau and β-Amyloid. Neurodegenerative Diseases, 7 1-3: 10-12. doi:10.1159/000283475 20   10 Cited 32 times in Scopus32 0
Gotz, J, Probst, A, Mistl, C, Nitsch, RM and Ehler, E (2000) Distinct role of protein phosphatase 2A subunit C alpha in the regulation of E-cadherin and beta-catenin during development. Mechanisms of Development, 93 1-2: 83-93. doi:10.1016/S0925-4773(00)00267-7 8   49 Cited 46 times in Scopus46 0
Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008) Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 1: 137-147. doi:10.1111/j.1460-9568.2008.06318.x 10   31 Cited 35 times in Scopus35 0
Schmidt K., Kins S., Schild A., Nitsch R.M., Hemmings B.A. and Gotz J. (2002) Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A. European Journal of Neuroscience, 16 11: 2039-2048. doi:10.1046/j.1460-9568.2002.02274.x 10   32 Cited 36 times in Scopus36 0
Götz, Jürgen, Ittner, Lars M. and Kins, Stefan (2006) Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?. Journal of Neurochemistry, 98 4: 993-1006. doi:10.1111/j.1471-4159.2006.03955.x 46   66 Cited 68 times in Scopus68 0
Tam, CW, Husmann, K, Clark, NC, Clark, JE, Lazar, Z, Ittner, LM, Gotz, J, Douglas, G, Grant, AD, Sugden, D, Poston, L, Poston, R, McFadzean, I, Marber, MS, Fischer, JA, Born, W and Brain, SD (2006) Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2. Circulation Research, 98 2: 262-270. doi:10.1161/01.RES.0000200737.638.65.58 9   23 0

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