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Fantino, E., Gangell, C.L., Hartl, D. and Sly, P.D. (2014) Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease. BMC Pulmonary Medicine, 14 1: 1-6. doi:10.1186/1471-2466-14-28 33   5 Cited 5 times in Scopus5 1
Gargus, JJ, Fantino, E and Gutman, GA (1998) A piece in the puzzle: an ion channel candidate gene for schizophrenia. Molecular Medicine Today, 4 12: 518-524. doi:10.1016/S1357-4310(98)01358-6 17   25 Cited 26 times in Scopus26 0
Matveenko, Maria, Banwell, Martin G., Joffe, Max, Wan, Soosan and Fantino, Emmanuelle (2009) Biological evaluation of ent-narciclasine, ent-lycoricidine, and certain enantiomerically-related congeners. Chemistry and Biodiversity, 6 5: 685-691. doi:10.1002/cbdv.200800319 31   7 Cited 7 times in Scopus7 0
Logan, Jayden, Chen, Linping, Gangell, Catherine, Sly, Peter D., Fantino, Emmanuelle and Liu, Kenneth (2014) Brief exposure to cigarette smoke impairs airway epithelial cell innate anti-viral defence. Toxicology in Vitro, 28 8: 1430-1435. doi:10.1016/j.tiv.2014.07.012 41   0 Cited 0 times in Scopus0 2
Chandy, KG, Fantino, E, Wittekindt, O, Kalman, K, Tong, L, Ho, T, Cahalan, MD, Gutman, GA, Crocq, MA, Ganguli, R, Nimgaonkar, V, Morris-Rosendahl, DJ and Gargus, JJ (1998). CAG repeats in a K+ channel gene, hKCA3: A candidate for schizophrenia and bipolar disorder?. In: Biophysical Journal. , , (A26-A26). . 21   1
Vargas, GA, Isas, JM, Fantino, E, Gargus, JJ and Haigler, HT (1998) CCG1/TAF(II)250 regulates epidermal growth factor receptor gene transcription in cell cycle mutant ts13. Journal of Cellular Physiology, 176 3: 642-647. doi:10.1002/(SICI)1097-4652(199809)176:3<642::AID-JCP21>3.0.CO;2-# 19   3 Cited 3 times in Scopus3 0
Zisman, Lawrence S., Jain, Ritu, Chin-Dusting, Jaye, Andrews, Karen, Court, Naomi, Fantino, Emmanuelle, Farrugia, Michelle and Burns, Christopher J. (2010). CYT387, a novel Jak1/Jak2 inhibitor, prevents progression of pulmonary arterial hypertension in the rat monocrotaline model. In: Meeting Abstracts. American Heart Association Scientific Session 2010, Chicago, United States, (). 13-17 November 2010. 83   0
Tyner, Jeffrey W., Bumm, Thomas G., Deininger, Jutta, Wood, Lisa, Aichberger, Karl J., Loriaux, Marc M., Druker, Brian J., Burns, Christopher J., Fantino, Emmanuelle and Deininger, Michael W. (2010) CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms. Blood, 115 25: 5232-5240. doi:10.1182/blood-2009-05-223727 40   79 Cited 85 times in Scopus85 0
Pardanani, A., Lasho, T., Smith, G., Burns, C. J., Fantino, E. and Tefferi, A. (2009) CYT387, a selective JAK1/JAK2 inhibitor: in vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients. Leukemia, 23 8: 1441-1445. doi:10.1038/leu.2009.50 37   68 Cited 71 times in Scopus71 3
Burns, Christopher J., Fantino, Emmanuelle, Phillips, Ian D., Su, Stephen, Harte, Michael F., Bukczynska, Patricia E., Frazzetto, Mark, Joffe, Max, Kruszelnicki, Irma, Wang, Bing, Wang, Yue, Wilson, Neil, Dilley, Rodney J., Wan, Soo S., Charman, Susan A., Shackleford, David M., Fida, Rosa, Malcontenti-Wilson, Cathy and Wilks, Andrew F. (2009) CYT997: a novel orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Molecular Cancer Therapeutics, 8 11: 3036-3045. doi:10.1158/1535-7163.MCT-09-0076 34   12 Cited 13 times in Scopus13 0
Burns, Christopher J., Harte, Michael F., Bu, Xianyong, Fantino, Emmanuelle, Giarrusso, Marilena, Joffe, Max, Kurek, Margarita, Legge, Fiona S., Razzino, Pasquale, Su, Stephen, Treutlein, Herbert, Wan, Soo San, Zeng, Jun and Wilks, Andrew F (2009) Discovery of 2-(alpha-methylbenzylamino) pyrazines as potent Type II inhibitors of FMS. Bioorganic & Medicinal Chemistry Letters, 19 4: 1206-1209. doi:10.1016/j.bmcl.2008.12.073 35   10 Cited 10 times in Scopus10 0
Feutrill, John, Bukczynska, Patricia, Burns, Christopher, Fantino, Emmanuelle, Harte, Michael, Kruszelnicki, Irma, Phillips, Ian, Su, Stephen, Tranberg, Lisa, Wang, Bing, Wang, Yue and Wilks, Andrew (2009). Discovery of CYT997, a potent vascular disrupting agent and inhibitor of tubulin polymerization. In: Abstracts of Papers of the American Chemical Society. 237th National Meeting of the American Chemical Society, Salt Lake City, USA, (). 22-26 March 2009. 45   0
Burns, Christopher J., Harte, Michael F., Bu, Xianyong, Fantino, Emmanuelle, Joffe, Max, Sikanyika, Harrison, Su, Stephen, Tranberg, C. Elisabet, Wilson, Neil, Charman, Susan A., Shackleford, David M. and Wilks, Andrew F. (2009) Discovery of CYT997: a structurally novel orally active microtubule targeting agent. Bioorganic & Medicinal Chemistry Letters, 19 16: 4639-4642. doi:10.1016/j.bmcl.2009.06.079 51   11 Cited 14 times in Scopus14 0
Williams, Neal K., Bamert, Rebecca S., Patel, Onisha, Wang, Christina, Walden, Patricia M., Wilks, Andrew F., Fantino, Emmanuelle, Rossjohn, Jamie and Lucet, Isabelle S. (2009) Dissecting specificity in the Janus Kinases: The structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains. Journal of Molecular Biology, 387 1: 219-232. doi:10.1016/j.jmb.2009.01.041 39   72 Cited 76 times in Scopus76 6
Fantino, E, Marguet, D and Lauquin, Gjm (1992) Downstream Activating Sequence Within the Coding Region of a Yeast Gene - Specific Binding Invitro of Rap1 Protein. Molecular & General Genetics, 236 1: 65-75. 27   24
Bumm, T., Tyner, J. W., Deininger, J., Loriaux, M., VanDyke, J., Druker, B. J., Burns, C. J., Fantino, E. and Deininger, M. W. N. (2008). Effects of CYT387, a potent novel JAK2 inhibitor on JAK2-V617F induced MPD. In: 50th Annual Meeting of the American Society of Hematology, San Francisco Ca, (316-317). 6-9 December 2008. 33   0
Baturcam, Engin, Yeo, Tiong Han, Schagen, Johanna, Thomas, Emma, Di-Masi, Janine, Phipps, Simon, Fantino, Emmanuelle, Sly, Peter and Spann, Kirsten (2014). Elevated hMPV, but not RSV, replication in the nasal epithelium of asthmatic adults is facilitated by an IFN-independent integrated stress response. In: Cytokine. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne Australia, (29-29). Oct 26-29, 2014. doi:10.1016/j.cyto.2014.07.013 20   0 0
Norman, Rosana E., Veerman, J. Lennert, Scott, James, Fantino, Emmanuelle, Bailie, Ross, Sly, Peter D. and Cleghorn, Geoffrey (2013) Environmental contributions to the leading causes of disease burden among Australian children. Journal of Pediatric Gastroenterology and Nutrition, 56 5: 481-484. doi:10.1097/MPG.0b013e3182848a23 139   0 Cited 0 times in Scopus0 3
Smith, Margaret J., Sharples, Robyn A., Evin, Genevieve, McLean, Catriona A., Dean, Brian, Pavey, Geoff, Fantino, Emmanuelle, Cotton, Richard G. H., Imaizumi, Kazunori, Masters, Colin L., Cappai, Roberto and Culvenor, Janetta G. (2004) Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex. Molecular Brain Research, 127 1-2: 128-135. doi:10.1016/j.molbrainres.2004.05.019 35   22 Cited 21 times in Scopus21 0
Bowen, T, Guy, CA, Craddock, N, Cardno, AG, Williams, NM, Spurlock, G, Murphy, KC, Jones, LA, Gray', M, Sanders, RD, McCarthy, G, Chandy, KG, Fantino, E, Kalman, K, Gutman, GA, Gargus, JJ, Williams, J, McGuffin, P, Owen, MJ and O'Donovan, MC (1998) Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia. Molecular Psychiatry, 3 3: 266-269. doi:10.1038/ 15   57 0
Marguet, D, Fantino, E and Lauquin, Gjm (1988) Gene Cloning From Yeast Chromosome-Specific Mini-Library Isolation of the Srp1-Related Dna-Sequence Located On Chromosome-Xv. Febs Letters, 234 2: 421-425. doi:10.1016/0014-5793(88)80129-7 16   6 Cited 4 times in Scopus4 0
Chandy, KG, Fantino, E, Kalman, K, Gutman, GA and Gargus, JJ (1997). Gene encoding neuronal calcium-activated potassium channel has polymorphic CAG repeats, a candidate role in excitotoxic neurodegeneration and maps to 22q11-q13, critical region for bipolar disease and schizophrenia disorder 4.. In: American Journal of Human Genetics. , , (A305-A305). . 21   1
Fantino, E, Soughayer, J, Tuscan, M and Gargus, JJ (1996). Growth factor activated cation channel isolated via functional cloning is mammalian homolog to yeast Sec62. In: Molecular Biology of the Cell. , , (67-67). . 22   0
Liu, Faye F., Peng, Cheng, Escher, Beate I., Fantino, Emmanuelle, Giles, Cindy, Were, Stephen, Duffy, Lesley and Ng, Jack C. (2013) Hanging drop: an in vitro air toxic exposure model using human lung cells in 2D and 3D structures. Journal of Hazardous Materials, 261 701-710. doi:10.1016/j.jhazmat.2013.01.027 52   2 Cited 2 times in Scopus2 0
Dror, V, Shamir, E, Ghanshani, S, Kimhi, R, Swartz, M, Barak, Y, Weizman, R, Avivi, L, Litmanovitch, T, Fantino, E, Kalman, K, Jones, EG, Chandy, KG, Gargus, JJ, Gutman, GA and Navon, R (1999) hKCa3/KCNN3 potassium channel gene: association of longer CAG repeats with schizophrenia in Israeli Ashkenazi Jews, expression in human tissues and localization to chromosome 1q21. Molecular Psychiatry, 4 3: 254-260. doi:10.1038/ 18   59 0
Chen, A., Lourie, R., Martin, M., Burr, L., Hasnain, S., Fantino, E., Bowler, S., Mcguckin, M. and Serisier, D. (2014). Human Neutrophil Elastase Activity and Matrix Metalloproteinase Activity Are Markers of Disease Severity in Non-Cf Bronchiectasis. In: Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2014 Annual Scientific Meetings, Adelaide Australia, (87-87). 4-9 April 2014. doi:10.1111/resp.12263_6 28   0 0
Liu, K., Franke, M., Fantino, E. and Sly, P. D. (2012). Influence of Growth Factors and Glucocorticoids in Media On Epithelial Cell Responses. In: Respirology. unknown, unknown, (54-54). unknown. 35   0
Chandy, KG, Fantino, E, Wittekindt, O, Kalman, K, Tong, LL, Ho, TH, Gutman, GA, Crocq, MA, Ganguli, R, Nimgaonkar, V, Morris-Rosendahl, DJ and Gargus, JJ (1998) Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?. Molecular Psychiatry, 3 1: 32-37. doi:10.1038/ 27   125 3
Antonarakis, SE, Blouin, JL, Lasseter, VK, Gehrig, C, Radhakrishna, U, Nestadt, G, Housman, DE, Kazazian, HH, Kalman, K, Gutman, G, Fantino, E, Chandy, KG, Gargus, JJ and Arm, E (1999) Lack of linkage or association between schizophrenia and the polymorphic trinucleotide repeat within the KCNN3 gene on chromosome 1q21. American Journal of Medical Genetics, 88 4: 348-351. doi:10.1002/(SICI)1096-8628(19990820)88:4<348::AID-AJMG11>3.0.CO;2-N 10   30 Cited 31 times in Scopus31 0
Bourke, DG, Palmer, J, Donohue, A, Feutrill, J, Andrau, L, Kling, M, Nguyen, T, McNally, M, Bu, X, Burns, C, Sikakanyika, H, Fantino, E, Kurek, M, Joffe, M, Wan, SS, Court, N and Bukczynska, P (2008). MEDI 95-N,4-Diphenylpyrimidin-2-amines as inhibitors of Janus kinases. In: Abstracts of Papers of the American Chemical Society. 236th National Meeting of the American-Chemical-Society, Philadelphia Pa, (). Aug 17-21, 2008. 55   0
Keys, DA, Lee, BS, Dodd, JA, Nguyen, TT, Vu, L, Fantino, E, Burson, LM, Nogi, Y and Nomura, M (1996) Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Genes & Development, 10 7: 887-903. doi:10.1101/gad.10.7.887 34   91 0
Burns, Christopher J., Bourke, David G., Andrau, Laura, Bu, Xianyong, Charman, Susan A., Donohue, Andrew C., Fantino, Emmanuelle, Farrugia, Michelle, Feutrill, John T., Joffe, Max, Kling, Marcel R., Kurek, Margarita, Nero, Tracy L., Nguyen, Thao, Palmer, James T., Phillips, Ian, Shackleford, David M, Sikanyika, Harrison, Styles, Michelle, Su, Stephen, Treutlein, Herbert, Zeng, Jun and Wilks, Andrew F. (2009) Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs). Bioorganic & Medicinal Chemistry Letters, 19 20: 5887-5892. doi:10.1016/j.bmcl.2009.08.071 45   28 Cited 30 times in Scopus30 0
Vargas, GA, Fantino, E, GeorgeNascimento, C, Gargus, JJ and Haigler, HT (1996) Reduced epidermal growth factor receptor expression in hypohidrotic ectodermal dysplasia and Tabby mice. Journal of Clinical Investigation, 97 11: 2426-2432. doi:10.1172/JCI118689 15   22 0
Feutrill, J., Andrau, L., Bourke, D. G., Bu, X. Y., Bukczynska, P., Bums, C., Court, N., Donohue, A., Fantino, E., Farrugia, M., Joffe, M., Kling, M., Kurek, M., Nero, T., Nguyen, T, Palmer, J. T., Sikanyika, H., Treutlein, H., Wan, S. S., Wilks, A. and Zeng, J. (2009). Small molecule inhibitors of Janus kinases. In: American Chemical Society National Meeting, Salt Lake City, UT, U.S.A., (). 22 -26 March 2009. 39   0
Walter, Mark, Lucet, Isabelle S., Patel, Onisha, Broughton, Sophie E., Bamert, Rebecca, Williams, Neal K., Fantino, Emmanuelle, Wilks, Andrew F. and Rossjohn, Jamie (2007) The 2.7 angstrom crystal structure of the autoinhibited human c-Fms kinase domain. Journal of Molecular Biology, 367 3: 839-847. doi:10.1016/j.jmb.2007.01.036 89   31 Cited 31 times in Scopus31 0
Burns, Christopher J., Fantino, Emmanuelle, Powell, Andrew K., Shnyder, Steven D., Cooper, Patricia A., Nelson, Stuart, Christophi, Christopher, Malcontenti-Wilson, Cathy, Dubljevic, Valentina, Harte, Michael F., Joffe, Max, Phillips, Ian D., Segal, David, Wilks, Andrew F. and Smith, Gregg D. (2011) The microtubule depolymerizing agent CYT997 causes extensive ablation of tumor vasculature in vivo. Journal of Pharmacology and Experimental Therapeutics, 339 3: 799-806. doi:10.1124/jpet.111.186965 50   6 Cited 6 times in Scopus6 0
Lucet, I. S., Fantino, E., Styles, M., Wilks, A. W. and Rossjohn, J. (2005). The structural basis of Janus Kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. In: Thirty-third meeting of the European Histamine Research Society, Cologne, Germany, (S89-S89). April 28–May 2 2004. 23   0
Lucet, Isabelle S., Fantino, Emmanuelle, Styles, Michelle, Bamert, Rebecca, Patel, Onisha, Broughton, Sophie E., Walter, Mark, Burns, Christopher J., Treutlein, Herbert, Wilks, Andrew F. and Rossjohn, Jamie (2006) The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood, 107 1: 176-183. doi:10.1182/blood-2005-06-2413 31   158 Cited 160 times in Scopus160 0
Li, T, Hu, X, Chandy, KG, Fantino, E, Kalman, K, Gutman, G, Gargus, JJ, Freeman, B, Murray, RM, Dawson, E, Liu, XH, Bruinvels, AT, Sham, PC and Collier, DA (1998) Transmission disequilibrium analysis of a triplet repeat within the hKCa3 gene using family trios with schizophrenia. Biochemical and Biophysical Research Communications, 251 2: 662-665. doi:10.1006/bbrc.1998.9484 25   27 Cited 27 times in Scopus27 0
Spann, Kirsten M., Baturcam, Engin, Schagen, Johanna, Jones, Carmen, Straub, Claire P., Preston, F. Maxine, Chen, Linping, Phipps, Simon, Sly, Peter D. and Fantino, Emmanuelle (2014) Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy. Thorax, 69 10: 918-925. doi:10.1136/thoraxjnl-2013-204908 56   4 Cited 3 times in Scopus3 9
Fantino, E., Gangell, C. L., Franke, M., Sly, P. D. and Arest, C. F. (2013). YKL-40 measured in BAL fluid but not in serum or urine is a biomarker of lung damage in children with CF. In: Abstracts of the Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, (61-61). 22-27 March 2013. doi:10.1111/resp.12046 39   0 0