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Inder, K., Harding, A., Plowman, S. J., Philips, M. R., Parton, R. G. and Hancock, J. F. (2008) Activation of the MAPK Module from Different Spatial Locations Generates Distinct System Outputs. Molecular Biology of the Cell, 19 11: 4776-4784. doi:10.1091/mbc.E08-04-0407 44   39 Cited 44 times in Scopus44 0
Behncken, S., Rowlinson, S. W., Clyde-Smith, J., Hancock, J. F. and Waters, M. J. (2000). A dimerization-dependent conformational change in the extracellular domain of the growth hormone receptor (GHR) is required for full signalling. In: 11th International Congress of Endocrinology. 11th International Congress of Endocrinology, Sydney, Australia, (438). 30 Oct - 2 Nov, 2000. 78  
Rowlinson, Scott W., Yoshizato, Hideo, Barclay, Johanna L., Brooks, Andrew J., Behncken, Stuart N., Kerr, Linda M., Millard, Kirstin, Palethorpe, Kathryn, Nielsen, Katherine, Clyde-Smith, Jodie, Hancock, John F. and Waters, Michael J. (2008) An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway. Nature Cell Biology, 10 6: 740-747. doi:10.1038/ncb1737 108   37 Cited 45 times in Scopus45 0
Crouthamel, Marykate, Abankwa, Daniel, Zhang, Li, DiLizio, Cherisse, Manning, David R., Hancock, John F. and Wedegaertner, Philip B. (2010) An N-terminal polybasic motif of G alpha(q) is required for signaling and influences membrane nanodomain distribution. Molecular Pharmacology, 78 4: 767-777. doi:10.1124/mol.110.066340 63   3 Cited 3 times in Scopus3 0
Abankwa, Daniel, Hanzal-Bayer, Michael, Ariotti, Nicolas, Plowman, Sarah J., Gorfe, Alemayehu A, Parton, Robert G., McCammon, J. Andrew and Hancock, John F. (2008) A novel switch region regulated H-ras membrane orientation and signal output. The EMBO journal, 27 5: 727-735. doi:10.1038/emboj.2008.10 78   76 Cited 80 times in Scopus80 0
Gobe, G., Zhang, X. J., Cuttle, L., Pat, B., Willgoss, D., Hancock, J., Barnard, R. T. and Endre, Z. (1999) Bcl-2 genes and growth factors in the pathology of ischaemic acute renal failure. Immunology and Cell Biology, 77 3: 279-286. doi:10.1046/j.1440-1711.1999.00826.x 105   34 Cited 41 times in Scopus41 0
Parton, RG, Hanzal-Bayer, M and Hancock, JF (2006) Biogenesis of caveolae: a structural model for caveolin-induced domain formation. Journal of Cell Science, 119 5: 787-796. doi:10.1242/jcs.02853 82   146 Cited 147 times in Scopus147 0
Fern├índez Rojo, Manuel, Gongora, Milena, Fitzsimmons, Rebecca L., Martel, Nick, Martin, Sheree D., Nixon, Susan, Brooks, Andrew J., Ikonomopoulou, Maria P., Martin, Sally, Lo, Harriet P., Myers, Stephen A., Restall, Christina, Ferguson, Charles, Pilch, Paul F., McGee, Sean L., Anderson, Robin L., Waters, Michael J., Hancock, John F., Grimmond, Sean M., Muscat, George E. and Parton, Robert G. (2013) Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Reports, 4 2: 238-247. doi:10.1016/j.celrep.2013.06.017 65   6 Cited 6 times in Scopus6 2
Parton, R. G. and Hancock, J. F. (2001) Caveolin and Ras function. Methods in Enzymology, 333 172-183. doi:10.1016/S0076-6879(01)33055-0 55   21 Cited 21 times in Scopus21 0
Wyse, B. D., Prior, I. A., Qian, H. W., Morrow, I. C., Nixon, S., Muncke, C., Kurzchalia, T. V., Thomas, W. G., Parton, R. G. and Hancock, J. F. (2003) Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. Journal of Biological Chemistry, 278 26: 23738-23746. doi:10.1074/jbc.M212892200 69   85 Cited 91 times in Scopus91 0
Hernandez-Deviez, D. J., Howes, M. T., Laval, S. H., Bushby, K., Hancock, J. F. and Parton, R. G. (2008) Caveolin regulates endocytosis of the muscle repair protein, dysferlin. Journal of Biological Chemistry, 283 10: 6476-6488. doi:10.1074/jbc.M708776200 22   44 Cited 46 times in Scopus46 1
Clyde-Smith, J., Silins, G., Gartside, M., Grimmond, S., Etheridge, M., Apolloni, A., Hayward, N. and Hancock, J. F. (2000) Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor. Journal of Biological Chemistry, 275 41: 32260-32267. doi:10.1074/jbc.M006087200 79   87 3
Chadda, Rahul, Howes, Mark T., Plowman, Sarah J., Hancock, John F., Parton, Robert G. and Mayor, Satyajit (2007) Cholesterol-Sensitive Cdc42 Activation Regulates Actin Polymerization for Endocytosis via the GEEC Pathway. Traffic, 8 6: 702-717. doi:10.1111/j.1600-0854.2007.00565.x 93   86 Cited 83 times in Scopus83 0
Howes, Mark T., Kirkham, Matthew, Riches, James, Cortese, Katia, Walser, Piers J., Simpson, Fiona, Hill, Michelle M., Jones, Alun, Lundmark, Richard, Lindsay, Margaret R., Hernandez-Deviez, Delia J., Hadzic, Gordana, McCluskey, Adam, Bashir, Rumasia, Liu, Libin, Pilch, Paul, McMahon, Harvey, Robinson, Phillip J., Hancock, John F., Mayor, Satyajit and Parton, Robert G. (2010) Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. Journal of Cell Biology, 190 4: 675-691. doi:10.1083/jcb.201002119 115   87 Cited 93 times in Scopus93 1
Prior, I. A. and Hancock, J. F. (2001) Compartmentalization of Ras proteins. Journal of Cell Science, 114 9: 1603-1608. 31   145
Walser, Piers, Ariotti, Nicholas, Howes, Mark, Ferguson, Charles, Webb, Richard, Schwudke, Dominik, Leneva, Natalya, Cho, Kwang-Jin, Cooper, Leanne, Rae, James, Floetenmeyer, Matthias, Oorschot, Viola M. J., Skoglund, Ulf, Simons, Kai, Hancock, John F. and Parton, Robert G. (2012) Constitutive formation of caveolae in a bacterium. Cell, 150 4: 752-763. doi:10.1016/j.cell.2012.06.042 84   17 Cited 18 times in Scopus18 13
Hill, Michelle M., Daud, Noor Huda, Aung, Cho Sanda, Loo, Dorothy, Martin, Sally, Murphy, Samantha, Black, Debra M., Barry, Rachael, Simpson, Fiona, Liu, Libin, Pilch, Paul F, Hancock, John F., Marie-Odile Parat and Parton, Robert G. (2012) Co-regulation of cell polarization and migration by caveolar proteins PTRF/cavin-1 and caveolin-1. PLoS One, 7 8: e43041.1-e43041.9. doi:10.1371/journal.pone.0043041 130 1 14 Cited 14 times in Scopus14 1
Hansen, M., Prior, I. A., Hughes, P. E., Oertli, B., Chou, F. L., Willumsen, B. M., Hancock, J. F. and Ginsberg, M. H. (2003) C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution. Biochemical And Biophysical Research Communications, 311 4: 829-838. doi:10.1016/j.bbrc.2003.10.074 81   14 Cited 15 times in Scopus15 0
Prior, I. A., Muncke, C., Parton, R. G. and Hancock, J. F. (2003) Direct visualization of Ras proteins in spatially distinct cell surface microdomains. Journal of Cell Biology, 160 2: 165-170. doi:10.1083/jcb.200209091 60   396 Cited 406 times in Scopus406 2
Roy, S., Luetterforst, R., Harding, A., Apolloni, A., Etheridge, M., Stang, E., Rolls, B., Hancock, J. F. and Parton, R. G. (1999) Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains. Nature Cell Biology, 1 2: 98-105. 102   353
Hancock, J. F. and Prior, I. A. (2005) Electron microscopic imaging of Ras signaling domains. Methods, 37 2: 165-172. doi:10.1016/j.ymeth.2005.05.018 48   25 Cited 25 times in Scopus25 1
Plowman, S. J., Ariotti, N., Goodall, A., Parton, R. G. and Hancock, J. F. (2008) Electrostatic interactions positively regulate K-Ras nanocluster formation and function. Molecular and Cellular Biology, 28 13: 4377-4385. doi:10.1128/MCB.00050-08 40   42 Cited 47 times in Scopus47 0
Kirkham, Matthew, Nixon, Susan J., Howes, Mark T., Abi-Rached, Laurent, Wakeham, Diane E., Hanzal-Bayer, Michael, Ferguson, Charles, Hill, Michelle M., Fernandez-Rojo, Manuel, Brown, Deborah A., Hancock, John F., Brodsky, Frances M. and Parton, Robert G. (2008) Evolutionary analysis and molecular dissection of caveola biogenesis. Journal of Cell Science, 121 12: 2075-2086. doi:10.1242/jcs.024588 53   43 Cited 47 times in Scopus47 0
Morrow, I. C., Rea, S., Martin, S., Prior, I. A., Prohaska, R., Hancock, J. F., James, D. E. and Parton, R. G. (2002) Flotillin-1/Reggie-2 traffics to surface raft domains via a novel Golgi-independent pathway - Identification of a novel membrane targeting domain and a role for palmitoylation. Journal of Biological Chemistry, 277 50: 48834-48841. doi:10.1074/jbc.M209082200 85   124 Cited 125 times in Scopus125 0
Belanis, L., Plowman, S., Rotblat, B., Hancock, J. F. and Kloog, Y. (2008) Galectin-1 is a novel structural component and a major regulator of H-Ras Nanoclusters. Molecular biology of the cell, 19 4: 1404-1414. doi:10.1091/mbc.E07-10-1053 8   58 Cited 61 times in Scopus61 0
Hancock, JF (2004) GPI-Anchor synthesis: Ras takes charge. Developmental Cell, 6 6: 743-745. doi:10.1016/j.devcel.2004.05.011 44   4 Cited 8 times in Scopus8 0
Prior, Ian A., Harding, Angus, Yan, Jun, Sluimer, Judith, Parton, Robert G. and Hancock, John F. (2001) GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. Nature Cell Biology, 3 4: 368-375. doi:10.1038/35070050 75   342 Cited 347 times in Scopus347 0
Apolloni, A., Prior, I. A., Lindsay, M., Parton, R. G. and Hancock, J. F. (2000) H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. Molecular & Cellular Biology, 20 7: 2475-2487. doi:10.1128/MCB.20.7.2475-2487.2000 48   251 Cited 262 times in Scopus262 0
Plowman, S. J., Muncke, C., Parton, R. G. and Hancock, J. F. (2005) H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proceedings of The National Academy of Sciences of The United States of America, 102 43: 15500-15505. doi:10.1073/pnas.0504114102 76   200 Cited 212 times in Scopus212 0
Roy, S., Wyse, B. and Hancock, J. F. (2002) H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis. Molecular And Cellular Biology, 22 14: 5128-5140. doi:10.1128/MCB.22.14.5128-5140.2002 64   92 Cited 95 times in Scopus95 0
Payne, Elizabeth, Bowles, Mark R., Don, Alistair, Hancock, John F. and McMillan, Nigel A. J. (2001) Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation. Journal of Virology, 75 9: 4150-4157. doi:10.1128/JVI.75.9.4150-4157.2001 36   22 Cited 25 times in Scopus25 0
Schroder, W. A., Buck, M., Cloonan, N., Hancock, J. F., Suhrbier, A., Sculley, T. and Bushell, G. (2007) Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signaling. Cellular Signalling, 19 6: 1279-1289. doi:10.1016/j.cellsig.2007.01.013 77   37 Cited 37 times in Scopus37 3
Ingelmo-Torres, M, Gonzalez-Moreno, E, Kassan, A, Hanzal-Bayer, M, Tebar, F, Herms, A, Grewal, T, Hancock, J. F., Enrich, C, Bosch, M, Gross, S. P., Parton, R. G. and Pol, A (2009) Hydrophobic and basic domains target proteins to lipid droplets. TRAFFIC, 10 12: 1785-1801. doi:10.1111/j.1600-0854.2009.00994.x 51   24 Cited 22 times in Scopus22 0
Harding, A., Hsu, V., Kornfeld, K. and Hancock, J. F. (2003) Identification of residues and domains of Raf important for function in vivo and in vitro. Journal of Biological Chemistry, 278 46: 45519-45527. doi:10.1074/jbc.M303106200 34   11 Cited 14 times in Scopus14 0
Nicolau, Dan V. (Jnr), Burrage, Kevin, Parton, Robert G. and Hancock, John F. (2006) Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Molecular and Cellular Biology, 26 1: 313-323. doi:10.1128/MCB.26.1.313-323.2006 64   102 Cited 106 times in Scopus106 1
Roy, Sandrine, Plowman, Sarah, Rotblat, Barak, Prior, Ian, Muncke, Cornelia, Grainger, Sarah, Parton, Robert, Henis, Yoav, Kloog, Yoel and Hancock, John (2005) Individual Palmitoyl Residues Serve Distinct Roles in H-ras Trafficking, Microlocalization, and Signaling. Molecular And Cellular Biology, 25 15: 6722-6733. doi:10.1128/MCB.25.15.6722-6733.2005 92   124 Cited 133 times in Scopus133 0
Carozzi, A. J., Roy, S., Morrow, I. C., Pol, A., Wyse, B., Clyde-Smith, J., Prior, I. A., Nixon, S. J., Hancock, J. F. and Parton, R. G. (2002) Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. Journal of Biological Chemistry, 277 20: 17944-17949. doi:10.1074/jbc.M110879200 156   38 Cited 39 times in Scopus39 0
McPherson, R. A., Harding, A. S., Roy, S., Lane, A. C., Hancock, J. F. and Sandrine, R (1999) Interactions of c-Raf-1 with phosphatidylserine and 14-3-3. Oncogene, 18 26: 3862-3869. doi:10.1038/sj.onc.1202730 24   49 Cited 47 times in Scopus47 0
Shalom-Feuerstein, R., Plowman, S. J., Rotblat, B., Ariotti, N., Tian, T., Hancock, J. F. and Kloog, Y. (2008) K-Ras Nanoclustering is Subverted by Overexpression of the Scaffold Protein Galectin-3. Cancer Research, 68 16: 6608-6616. doi:10.1158/0008-5472.CAN-08-1117 15   36 Cited 46 times in Scopus46 0
Hanzal-Bayer, M. F. and Hancock, J. F. (2007) Lipid rafts and membrane traffic. FEBS Letters, 581 11: 2098-2104. doi:10.1016/j.febslet.2007.03.019 74   182 Cited 185 times in Scopus185 0
Parton, R. G. and Hancock, J. F. (2004) Lipid rafts and plasma membrane microorganization: insights from Ras. Trends In Cell Biology, 14 3: 141-147. doi:10.1016/j.tcb.2004.02.001 52   130 Cited 128 times in Scopus128 0
Hancock, John F. (2006) Lipid rafts: contentious only from simplistic standpoints. Nature Reviews Molecular Cell Biology, 7 6: 456-462. doi:10.1038/nrm1925 72   475 Cited 484 times in Scopus484 0
Astuti, P, Pike, T, Widberg, C, Payne, E, Harding, A, Hancock, J and Gabrielli, B (2009) MAPK pathway activation delays G(2)/M progression by destabilizing Cdc25B. Journal of Biological Chemistry, 284 49: 33781-33788. doi:10.1074/jbc.M109.027516 88   16 Cited 17 times in Scopus17 0
Harding, A., Giles, N., Burgess, A., Hancock, J. F. and Gabrielli, B. G. (2003) Mechanism of mitosis-specific activation of MEK1. Journal of Biological Chemistry, 278 19: 16747-16754. doi:10.1074/jbc.M301015200 53   39 Cited 40 times in Scopus40 0
Abankwa, D., Gorfe, A. A. and Hancock, J. F. (2008) Mechanisms of Ras membrane organization and signaling. Cell Cycle, 7 17: 2667-2673. doi:10.4161/cc.7.17.6596 22   26 Cited 30 times in Scopus30 0
Burrage, K., Hancock, J., Leier, A. and Nicolau, D. V, (2007) Modelling and simulation techniques for membrane biology. Briefings In Bioinformatics, 8 4: 234-244. doi:10.1093/bib/bbm033 52   22 Cited 22 times in Scopus22 0
Wilkins, Simon J., Yoong, Simon, Verkade, Heather, Mizoguchi, Takamasa, Plowman, Sarah J., Hancock, John F., Kikuchi, Yutaka, Heath, Joan K. and Perkins, Andrew C. (2008) Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation. Developmental Biology, 314 1: 12-22. doi:10.1016/j.ydbio.2007.10.050 67   18 Cited 19 times in Scopus19 0
Teng, L., Buck, M., Hancock, J., Clarke, R., Samaratunga, H., Schirra, H., Zenzmaier, C., Berger, P., Catto, J., Yaxley, J., Gianduzzo, T., Coughlin, G., Lavin, M. and Gardiner, R. (2010). Multiple markers in prostate cancer detection in ejaculate. In: URS, USANZ Meeting 2010, Nelson, New Zealand, (). 10-12 November, 2010. 52  
Bastiani, M, Liu, L, Hill, M. M., Jedrychowski, M. P., Nixon, S. J., Lo, H. P., Abankwa, D, Luetterforst, R, Fernandez-Rojo, M, Breen, M. R., Gygi, S. P., Vinten, J, Walser, P. J., North, K. N., Hancock, J. F., Pilch, P. F. and Parton, R. G. (2009) MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. The Journal of Cell Biology, 185 7: 1259-1273. doi:10.1083/jcb.200903053 68   84 Cited 85 times in Scopus85 0
Inder, Kerry L., Hill, Michelle M. and Hancock, John F. (2010) Nucleophosmin and nucleolin regulate K-Ras signaling. Communicative and Integrative Biology, 3 2: 188-190. doi:10.4161/cib.3.2.10923 41 38 Cited 3 times in Scopus3 0

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