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Inder, K., Harding, A., Plowman, S. J., Philips, M. R., Parton, R. G. and Hancock, J. F. (2008) Activation of the MAPK Module from Different Spatial Locations Generates Distinct System Outputs. Molecular Biology of the Cell, 19 11: 4776-4784. doi:10.1091/mbc.E08-04-0407 38   39 Cited 44 times in Scopus44 0
Behncken, S., Rowlinson, S. W., Clyde-Smith, J., Hancock, J. F. and Waters, M. J. (2000). A dimerization-dependent conformational change in the extracellular domain of the growth hormone receptor (GHR) is required for full signalling. In: 11th International Congress of Endocrinology. 11th International Congress of Endocrinology, Sydney, Australia, (438). 30 Oct - 2 Nov, 2000. 72  
Rowlinson, Scott W., Yoshizato, Hideo, Barclay, Johanna L., Brooks, Andrew J., Behncken, Stuart N., Kerr, Linda M., Millard, Kirstin, Palethorpe, Kathryn, Nielsen, Katherine, Clyde-Smith, Jodie, Hancock, John F. and Waters, Michael J. (2008) An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway. Nature Cell Biology, 10 6: 740-747. doi:10.1038/ncb1737 102   35 Cited 44 times in Scopus44 0
Crouthamel, Marykate, Abankwa, Daniel, Zhang, Li, DiLizio, Cherisse, Manning, David R., Hancock, John F. and Wedegaertner, Philip B. (2010) An N-terminal polybasic motif of G alpha(q) is required for signaling and influences membrane nanodomain distribution. Molecular Pharmacology, 78 4: 767-777. doi:10.1124/mol.110.066340 63   3 Cited 3 times in Scopus3 0
Abankwa, Daniel, Hanzal-Bayer, Michael, Ariotti, Nicolas, Plowman, Sarah J., Gorfe, Alemayehu A, Parton, Robert G., McCammon, J. Andrew and Hancock, John F. (2008) A novel switch region regulated H-ras membrane orientation and signal output. The EMBO journal, 27 5: 727-735. doi:10.1038/emboj.2008.10 76   72 Cited 75 times in Scopus75 0
Gobe, G., Zhang, X. J., Cuttle, L., Pat, B., Willgoss, D., Hancock, J., Barnard, R. T. and Endre, Z. (1999) Bcl-2 genes and growth factors in the pathology of ischaemic acute renal failure. Immunology and Cell Biology, 77 3: 279-286. doi:10.1046/j.1440-1711.1999.00826.x 103   34 Cited 41 times in Scopus41 0
Parton, RG, Hanzal-Bayer, M and Hancock, JF (2006) Biogenesis of caveolae: a structural model for caveolin-induced domain formation. Journal of Cell Science, 119 5: 787-796. doi:10.1242/jcs.02853 80   144 Cited 146 times in Scopus146 0
Fern├índez Rojo, Manuel, Gongora, Milena, Fitzsimmons, Rebecca L., Martel, Nick, Martin, Sheree D., Nixon, Susan, Brooks, Andrew J., Ikonomopoulou, Maria P., Martin, Sally, Lo, Harriet P., Myers, Stephen A., Restall, Christina, Ferguson, Charles, Pilch, Paul F., McGee, Sean L., Anderson, Robin L., Waters, Michael J., Hancock, John F., Grimmond, Sean M., Muscat, George E. and Parton, Robert G. (2013) Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Reports, 4 2: 238-247. doi:10.1016/j.celrep.2013.06.017 63   6 Cited 6 times in Scopus6 2
Parton, R. G. and Hancock, J. F. (2001) Caveolin and Ras function. Methods in Enzymology, 333 172-183. doi:10.1016/S0076-6879(01)33055-0 54   21 Cited 21 times in Scopus21 0
Wyse, B. D., Prior, I. A., Qian, H. W., Morrow, I. C., Nixon, S., Muncke, C., Kurzchalia, T. V., Thomas, W. G., Parton, R. G. and Hancock, J. F. (2003) Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. Journal of Biological Chemistry, 278 26: 23738-23746. doi:10.1074/jbc.M212892200 68   84 Cited 91 times in Scopus91 0
Hernandez-Deviez, D. J., Howes, M. T., Laval, S. H., Bushby, K., Hancock, J. F. and Parton, R. G. (2008) Caveolin regulates endocytosis of the muscle repair protein, dysferlin. Journal of Biological Chemistry, 283 10: 6476-6488. doi:10.1074/jbc.M708776200 22   44 Cited 46 times in Scopus46 1
Clyde-Smith, J., Silins, G., Gartside, M., Grimmond, S., Etheridge, M., Apolloni, A., Hayward, N. and Hancock, J. F. (2000) Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor. Journal of Biological Chemistry, 275 41: 32260-32267. doi:10.1074/jbc.M006087200 76   86 3
Chadda, Rahul, Howes, Mark T., Plowman, Sarah J., Hancock, John F., Parton, Robert G. and Mayor, Satyajit (2007) Cholesterol-Sensitive Cdc42 Activation Regulates Actin Polymerization for Endocytosis via the GEEC Pathway. Traffic, 8 6: 702-717. doi:10.1111/j.1600-0854.2007.00565.x 89   83 Cited 80 times in Scopus80 0
Howes, Mark T., Kirkham, Matthew, Riches, James, Cortese, Katia, Walser, Piers J., Simpson, Fiona, Hill, Michelle M., Jones, Alun, Lundmark, Richard, Lindsay, Margaret R., Hernandez-Deviez, Delia J., Hadzic, Gordana, McCluskey, Adam, Bashir, Rumasia, Liu, Libin, Pilch, Paul, McMahon, Harvey, Robinson, Phillip J., Hancock, John F., Mayor, Satyajit and Parton, Robert G. (2010) Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. Journal of Cell Biology, 190 4: 675-691. doi:10.1083/jcb.201002119 113   83 Cited 86 times in Scopus86 1
Prior, I. A. and Hancock, J. F. (2001) Compartmentalization of Ras proteins. Journal of Cell Science, 114 9: 1603-1608. 29   144
Walser, Piers, Ariotti, Nicholas, Howes, Mark, Ferguson, Charles, Webb, Richard, Schwudke, Dominik, Leneva, Natalya, Cho, Kwang-Jin, Cooper, Leanne, Rae, James, Floetenmeyer, Matthias, Oorschot, Viola M. J., Skoglund, Ulf, Simons, Kai, Hancock, John F. and Parton, Robert G. (2012) Constitutive formation of caveolae in a bacterium. Cell, 150 4: 752-763. doi:10.1016/j.cell.2012.06.042 81   16 Cited 17 times in Scopus17 13
Hill, Michelle M., Daud, Noor Huda, Aung, Cho Sanda, Loo, Dorothy, Martin, Sally, Murphy, Samantha, Black, Debra M., Barry, Rachael, Simpson, Fiona, Liu, Libin, Pilch, Paul F, Hancock, John F., Marie-Odile Parat and Parton, Robert G. (2012) Co-regulation of cell polarization and migration by caveolar proteins PTRF/cavin-1 and caveolin-1. PLoS One, 7 8: e43041.1-e43041.9. doi:10.1371/journal.pone.0043041 128 1 13 Cited 13 times in Scopus13 1
Hansen, M., Prior, I. A., Hughes, P. E., Oertli, B., Chou, F. L., Willumsen, B. M., Hancock, J. F. and Ginsberg, M. H. (2003) C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution. Biochemical And Biophysical Research Communications, 311 4: 829-838. doi:10.1016/j.bbrc.2003.10.074 80   13 Cited 15 times in Scopus15 0
Prior, I. A., Muncke, C., Parton, R. G. and Hancock, J. F. (2003) Direct visualization of Ras proteins in spatially distinct cell surface microdomains. Journal of Cell Biology, 160 2: 165-170. doi:10.1083/jcb.200209091 60   388 Cited 397 times in Scopus397 2
Roy, S., Luetterforst, R., Harding, A., Apolloni, A., Etheridge, M., Stang, E., Rolls, B., Hancock, J. F. and Parton, R. G. (1999) Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains. Nature Cell Biology, 1 2: 98-105. 96   349
Hancock, J. F. and Prior, I. A. (2005) Electron microscopic imaging of Ras signaling domains. Methods, 37 2: 165-172. doi:10.1016/j.ymeth.2005.05.018 48   24 Cited 24 times in Scopus24 1
Plowman, S. J., Ariotti, N., Goodall, A., Parton, R. G. and Hancock, J. F. (2008) Electrostatic interactions positively regulate K-Ras nanocluster formation and function. Molecular and Cellular Biology, 28 13: 4377-4385. doi:10.1128/MCB.00050-08 39   39 Cited 43 times in Scopus43 0
Kirkham, Matthew, Nixon, Susan J., Howes, Mark T., Abi-Rached, Laurent, Wakeham, Diane E., Hanzal-Bayer, Michael, Ferguson, Charles, Hill, Michelle M., Fernandez-Rojo, Manuel, Brown, Deborah A., Hancock, John F., Brodsky, Frances M. and Parton, Robert G. (2008) Evolutionary analysis and molecular dissection of caveola biogenesis. Journal of Cell Science, 121 12: 2075-2086. doi:10.1242/jcs.024588 52   41 Cited 46 times in Scopus46 0
Morrow, I. C., Rea, S., Martin, S., Prior, I. A., Prohaska, R., Hancock, J. F., James, D. E. and Parton, R. G. (2002) Flotillin-1/Reggie-2 traffics to surface raft domains via a novel Golgi-independent pathway - Identification of a novel membrane targeting domain and a role for palmitoylation. Journal of Biological Chemistry, 277 50: 48834-48841. doi:10.1074/jbc.M209082200 84   124 Cited 125 times in Scopus125 0
Belanis, L., Plowman, S., Rotblat, B., Hancock, J. F. and Kloog, Y. (2008) Galectin-1 is a novel structural component and a major regulator of H-Ras Nanoclusters. Molecular biology of the cell, 19 4: 1404-1414. doi:10.1091/mbc.E07-10-1053 7   55 Cited 59 times in Scopus59 0
Hancock, JF (2004) GPI-Anchor synthesis: Ras takes charge. Developmental Cell, 6 6: 743-745. doi:10.1016/j.devcel.2004.05.011 43   4 Cited 8 times in Scopus8 0
Prior, Ian A., Harding, Angus, Yan, Jun, Sluimer, Judith, Parton, Robert G. and Hancock, John F. (2001) GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. Nature Cell Biology, 3 4: 368-375. doi:10.1038/35070050 71   338 Cited 345 times in Scopus345 0
Apolloni, A., Prior, I. A., Lindsay, M., Parton, R. G. and Hancock, J. F. (2000) H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. Molecular & Cellular Biology, 20 7: 2475-2487. doi:10.1128/MCB.20.7.2475-2487.2000 48   249 Cited 259 times in Scopus259 0
Plowman, S. J., Muncke, C., Parton, R. G. and Hancock, J. F. (2005) H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton. Proceedings of The National Academy of Sciences of The United States of America, 102 43: 15500-15505. doi:10.1073/pnas.0504114102 76   197 Cited 207 times in Scopus207 0
Roy, S., Wyse, B. and Hancock, J. F. (2002) H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis. Molecular And Cellular Biology, 22 14: 5128-5140. doi:10.1128/MCB.22.14.5128-5140.2002 64   92 Cited 95 times in Scopus95 0
Payne, Elizabeth, Bowles, Mark R., Don, Alistair, Hancock, John F. and McMillan, Nigel A. J. (2001) Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferation. Journal of Virology, 75 9: 4150-4157. doi:10.1128/JVI.75.9.4150-4157.2001 34   22 Cited 25 times in Scopus25 0
Schroder, W. A., Buck, M., Cloonan, N., Hancock, J. F., Suhrbier, A., Sculley, T. and Bushell, G. (2007) Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signaling. Cellular Signalling, 19 6: 1279-1289. doi:10.1016/j.cellsig.2007.01.013 76   37 Cited 37 times in Scopus37 3
Ingelmo-Torres, M, Gonzalez-Moreno, E, Kassan, A, Hanzal-Bayer, M, Tebar, F, Herms, A, Grewal, T, Hancock, J. F., Enrich, C, Bosch, M, Gross, S. P., Parton, R. G. and Pol, A (2009) Hydrophobic and basic domains target proteins to lipid droplets. TRAFFIC, 10 12: 1785-1801. doi:10.1111/j.1600-0854.2009.00994.x 49   23 Cited 22 times in Scopus22 0
Harding, A., Hsu, V., Kornfeld, K. and Hancock, J. F. (2003) Identification of residues and domains of Raf important for function in vivo and in vitro. Journal of Biological Chemistry, 278 46: 45519-45527. doi:10.1074/jbc.M303106200 33   11 Cited 14 times in Scopus14 0
Nicolau, Dan V. (Jnr), Burrage, Kevin, Parton, Robert G. and Hancock, John F. (2006) Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane. Molecular and Cellular Biology, 26 1: 313-323. doi:10.1128/MCB.26.1.313-323.2006 63   100 Cited 106 times in Scopus106 1
Roy, Sandrine, Plowman, Sarah, Rotblat, Barak, Prior, Ian, Muncke, Cornelia, Grainger, Sarah, Parton, Robert, Henis, Yoav, Kloog, Yoel and Hancock, John (2005) Individual Palmitoyl Residues Serve Distinct Roles in H-ras Trafficking, Microlocalization, and Signaling. Molecular And Cellular Biology, 25 15: 6722-6733. doi:10.1128/MCB.25.15.6722-6733.2005 89   123 Cited 132 times in Scopus132 0
Carozzi, A. J., Roy, S., Morrow, I. C., Pol, A., Wyse, B., Clyde-Smith, J., Prior, I. A., Nixon, S. J., Hancock, J. F. and Parton, R. G. (2002) Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. Journal of Biological Chemistry, 277 20: 17944-17949. doi:10.1074/jbc.M110879200 154   38 Cited 39 times in Scopus39 0
McPherson, R. A., Harding, A. S., Roy, S., Lane, A. C., Hancock, J. F. and Sandrine, R (1999) Interactions of c-Raf-1 with phosphatidylserine and 14-3-3. Oncogene, 18 26: 3862-3869. doi:10.1038/sj.onc.1202730 23   49 Cited 47 times in Scopus47 0
Shalom-Feuerstein, R., Plowman, S. J., Rotblat, B., Ariotti, N., Tian, T., Hancock, J. F. and Kloog, Y. (2008) K-Ras Nanoclustering is Subverted by Overexpression of the Scaffold Protein Galectin-3. Cancer Research, 68 16: 6608-6616. doi:10.1158/0008-5472.CAN-08-1117 14   35 Cited 43 times in Scopus43 0
Hanzal-Bayer, M. F. and Hancock, J. F. (2007) Lipid rafts and membrane traffic. FEBS Letters, 581 11: 2098-2104. doi:10.1016/j.febslet.2007.03.019 73   179 Cited 180 times in Scopus180 0
Parton, R. G. and Hancock, J. F. (2004) Lipid rafts and plasma membrane microorganization: insights from Ras. Trends In Cell Biology, 14 3: 141-147. doi:10.1016/j.tcb.2004.02.001 52   130 Cited 128 times in Scopus128 0
Hancock, John F. (2006) Lipid rafts: contentious only from simplistic standpoints. Nature Reviews Molecular Cell Biology, 7 6: 456-462. doi:10.1038/nrm1925 68   473 Cited 483 times in Scopus483 0
Astuti, P, Pike, T, Widberg, C, Payne, E, Harding, A, Hancock, J and Gabrielli, B (2009) MAPK pathway activation delays G(2)/M progression by destabilizing Cdc25B. Journal of Biological Chemistry, 284 49: 33781-33788. doi:10.1074/jbc.M109.027516 87   15 Cited 16 times in Scopus16 0
Harding, A., Giles, N., Burgess, A., Hancock, J. F. and Gabrielli, B. G. (2003) Mechanism of mitosis-specific activation of MEK1. Journal of Biological Chemistry, 278 19: 16747-16754. doi:10.1074/jbc.M301015200 52   39 Cited 40 times in Scopus40 0
Abankwa, D., Gorfe, A. A. and Hancock, J. F. (2008) Mechanisms of Ras membrane organization and signaling. Cell Cycle, 7 17: 2667-2673. doi:10.4161/cc.7.17.6596 22   25 Cited 27 times in Scopus27 0
Burrage, K., Hancock, J., Leier, A. and Nicolau, D. V, (2007) Modelling and simulation techniques for membrane biology. Briefings In Bioinformatics, 8 4: 234-244. doi:10.1093/bib/bbm033 52   21 Cited 22 times in Scopus22 0
Wilkins, Simon J., Yoong, Simon, Verkade, Heather, Mizoguchi, Takamasa, Plowman, Sarah J., Hancock, John F., Kikuchi, Yutaka, Heath, Joan K. and Perkins, Andrew C. (2008) Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation. Developmental Biology, 314 1: 12-22. doi:10.1016/j.ydbio.2007.10.050 67   18 Cited 19 times in Scopus19 0
Teng, L., Buck, M., Hancock, J., Clarke, R., Samaratunga, H., Schirra, H., Zenzmaier, C., Berger, P., Catto, J., Yaxley, J., Gianduzzo, T., Coughlin, G., Lavin, M. and Gardiner, R. (2010). Multiple markers in prostate cancer detection in ejaculate. In: URS, USANZ Meeting 2010, Nelson, New Zealand, (). 10-12 November, 2010. 52  
Bastiani, M, Liu, L, Hill, M. M., Jedrychowski, M. P., Nixon, S. J., Lo, H. P., Abankwa, D, Luetterforst, R, Fernandez-Rojo, M, Breen, M. R., Gygi, S. P., Vinten, J, Walser, P. J., North, K. N., Hancock, J. F., Pilch, P. F. and Parton, R. G. (2009) MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. The Journal of Cell Biology, 185 7: 1259-1273. doi:10.1083/jcb.200903053 68   79 Cited 82 times in Scopus82 0
Inder, Kerry L., Hill, Michelle M. and Hancock, John F. (2010) Nucleophosmin and nucleolin regulate K-Ras signaling. Communicative and Integrative Biology, 3 2: 188-190. doi:10.4161/cib.3.2.10923 40 36 Cited 3 times in Scopus3 0

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