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Duggleby, R.G., McCourt, J. A. and Guddat, L. W. (2005). 3D structure of the overlapping sulfonylurea and imidazolinone herbicide binding sites in acetohydroxyacid synthase. In: 9th Int Congress on Amino Acids & Proteins. 9th Int Congress on Amino Acids & Proteins, Vienna, (Abstract). 8-12 Aug, 2005. 164  
de Jersey, John, Holý, Antonín, Hocková, Dana, Naesens, Lieve, Keough, Dianne T. and Guddat, Luke W. (2011) 6-Oxopurine phosphoribosyltransferase: A target for the development of antimalarial drugs. Current Topics in Medicinal Chemistry, 11 16: 2085-2102. doi:10.2174/156802611796575911 127 2 14 Cited 15 times in Scopus15 0
Pue, Nason and Guddat, Luke W. (2013) Acetohydroxyacid synthase: A target for antimicrobial drug discovery. Current Pharmaceutical Design, 19 1-17. 120 5 Cited 3 times in Scopus3
Keough, Dianne T., Špaček, Petr, Hocková, Dana, Tichý, Tomáš, Vrbková, Silvie, Slavětínská, Lenka, Janeba, Zlatko, Naesens, Lieve, Edstein, Michael D., Chavchich, Marina, Wang, Tzu-Hsuan, de Jersey, John and Guddat, Luke W. (2013) Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. Journal of Medicinal Chemistry, 56 6: 2513-2526. doi:10.1021/jm301893b 46   9 Cited 10 times in Scopus10 0
Liu, Ligong, Li, Caiping, Cochran, Siska, Feder, Daniel, Guddat, Luke W. and Ferro, Vito (2012) A focused sulfated glycoconjugate Ugi library for probing heparan sulfate-binding angiogenic growth factors. Bioorganic & Medicinal Chemistry Letters, 22 19: 6190-6194. doi:10.1016/j.bmcl.2012.08.001 52   2 Cited 1 times in Scopus1 1
Skinner-Adams, Tina S., Guddat, Luke W., Gardiner, Donald L., McCarthy, James S. and Andrews, Katherine T. (2005) Aspartic proteases of Plasmodium falciparum as the target of HIV-1 protease inhibitors - Reply. Journal of Infectious Diseases, 191 8: 1382-1383. doi:10.1086/428782 105   3 Cited 12 times in Scopus12 0
Keough, Dianne T., Hockova, Dana, Janeba, Zlatko, Wang, Tzu-Hsuan, Naesens, Lieve, Edstein, Michael D., Chavchich, Marina and Guddat, Luke W. (2015) Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their prodrugs as antimalarial agents. Journal of Medicinal Chemistry, 58 2: 827-846. doi:10.1021/jm501416t 11   1 Cited 2 times in Scopus2 0
Wong, Sze-Ho, Lonhienne, Thierry G. A., Winzor, Donald J., Schenk, Gerhard and Guddat, Luke W. (2012) Bacterial and plant ketol-acid reductoisomerases have different mechanisms of induced fit during the catalytic cycle. Journal of Molecular Biology, 424 3-4: 168-179. doi:10.1016/j.jmb.2012.09.018 86   3 Cited 3 times in Scopus3 0
Schenk, Gerhard, Mitić, Nataša, Gahan, Lawrence R., Ollis, David L., McGeary, Ross P. and Guddat, Luke W. (2012) Binuclear metallohydrolases: Complex mechanistic strategies for a simple chemical reaction. Accounts of Chemical Research, 45 9: 1593-1603. doi:10.1021/ar300067g 94   18 Cited 20 times in Scopus20 0
Wang, Jianguo, Tan, Haizhong, Li, Yonghong, Ma, Yi, Li, Zhengming and Guddat, Luke W. (2011) Chemical synthesis, in vitro acetohydroxyacid synthase (AHAS) inhibition, herbicidal activity, and computational studies of isatin derivatives. Journal of Agricultural and Food Chemistry, 59 18: 9892-9900. doi:10.1021/jf2021607 64   9 Cited 9 times in Scopus9 0
Leung, Eleanor W. W. and Guddat, Luke W. (2009) Conformational changes in a plant ketol-acid reductoisomerase upon Mg2+ and NADPH binding as revealed by two crystal structures. Journal of Molecular Biology, 389 1: 167-182. doi:10.1016/j.jmb.2009.04.012 66   13 Cited 13 times in Scopus13 0
Hamilton, S. E., Guddat, L. W., McAlpine, A. S., Hume, D. A., De Jersey, J. and Martin, J. L. (1999). Crystallisation of a mammalian purple acid phosphatase. In: 24th Annual Lorne Conference on Protein Structure and Function. 24th Annual Lorne Conference on Protein Structure and Functin, Erskine House, Lorne, Vic., (C10). 7-11 February, 1999. 61  
Edeling, M. A., Guddat, L. W., Fabianek, R. A., Halliday, J. A., Jones, A., Thony-Meyer, L. and Martin, J. L. (2001) Crystallization and preliminary diffraction studies of native and selenomethionine CcmG (CycY, DsbE). Acta Crystallographica Section D-Biological Crystallography, D57 9: 1293-1295. doi:10.1107/S0907444901009982 89   10 Cited 10 times in Scopus10 0
Millers, E. K. I., Masci, P. P., Lavin, M. F., de Jersey, J. and Guddat, L. W. (2006) Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis. Acta Crystallographica Section F-structural Biology And Crystallization Communications, 62 642-645. doi:10.1107/S1744309106019099 72   5 Cited 5 times in Scopus5 0
Schenk, G., Carrington, L., Hamilton, S. E., De Jersey, J. and Guddat, L. W. (1999) Crystallization and preliminary X-ray diffraction data for a purple acid phosphastase from sweet potato. Acta Crystallographica. Section D, Biological Crystallography, D55 2051-2052. doi:10.1107/S0907444999012597 70   11 Cited 15 times in Scopus15 0
Guddat, L. W., McAlpine, A. S., Hume, D. A., De Jersey, J., Hamilton, S. E. and Martin, J. L. (1999) Crystallization and preliminary X-ray diffraction studies of mammalian purple acid phosphatase. Acta Crystallographica. Section D, Biological Crystallography, 55 8: 1462-1464. doi:10.1107/S0907444999006241 61   3 Cited 2 times in Scopus2 0
Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2004) Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl. Acta Crystallographica Section D-biological Crystallography, 60 153-155. doi:10.1107/S0907444903025423 46   22 Cited 21 times in Scopus21 0
Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2001). Crystallization of the catalytic subunit of Saccharomyces cerevisiae acetohydroxyacid synthase. In: Acta crystallographica. Section D, Biological crystallography: Papers presented at COMBIO 2001. COMBIO 2001, Canberra, ACT, Australia, (1321-1323). 1-4 October, 2001. doi:10.1107/S0907444901011635 51   22 Cited 23 times in Scopus23 0
Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2001) Crystallization of the catalytic subunit of Saccharomyces cerevisiae acetohydroyacid synthase. Acta Crystallographica Section D, D57 1321-1323. 33  
Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2002) Crystallization of the FAD-independent acetolactate synthase of Klebsiella pneumoniae. Acta Crystallographica Section D - Biological Crystallography, D58 1237-1239. doi:10.1107/S0907444902008132 66   7 Cited 7 times in Scopus7 0
Schenk, G., Carrington, L., Valizadeh, M., De Jersey, J., Hamilton, S. E. and Guddat, L.W. (2003). Crystal structure and mechanism of a purple acid phosphatase from sweet potato: an enzyme with a novel Fe-Mn binuclear metal centre. In: International Conference on Biological Inorganic Chemistry. International Conference on Biological Inorganic Chemistry, Cairns, (Abstract). 19-23 July, 2003. 205  
Duggleby, R.G., Tyagi, R., Duquerroy, S., Navaza, J. and Guddat, L. W. (2005). Crystal structure of Escherichia coli ketol-acid reductoisomerase. In: East Coast Protein Meeting. East Coast Protein Meeting, Coffs Harbour, (Abstract). 24-26 June, 2005. 42  
Guddat, L. W., McAlpine, A. S., Hume, D. A., Hamilton, S. E., De Jersey, J. and Martin, J. L. (1999) Crystal structure of mammalian purple acid phosphatase. Structure With Folding & Design, 7 7: 757-767. doi:10.1016/S0969-2126(99)80100-2 93   129 Cited 128 times in Scopus128 0
Guddat, L. W., McAlpine, A. S., Hume, D. A., Hamilton, S. E, De Jersey, J. and Martin, J. L. (1999). Crystal structure of mammalian purple acid phosphatase: An enzyme with a binuclear metal centre. In: Combined Conference Abstracts: 43rd Annual ASBMB, 18th Annual ANZSCDB and 39th Annual ASPP. ComBio 99, Conrad Jupiters, Gold Coast, (Sym-05-01). 27-30 September, 1999. 64  
Millers, E. I., Masci, P., Lavin, M. F., De Jersey, J. and Guddat, L. W. (2005). Crystal structure of textilinin-1. In: East Coast Protein Meeting. East Coast Protein Meeting, Coffs Harbour, (Abstract). 24-26 June, 2005. 58  
Millers, Emma-Karin K., Trabi, Manuela, Masci, Paul P., Lavin, Martin F., de Jersey, John and Guddat, Luke W. (2009) Crystal structure of textilinin-1, a Kunitz-type serine protease inhibitor from the venom of the Australian common brown snake (Pseudonaja textilis). FEBS Journal, 276 11: 3163-3175. doi:10.1111/j.1742-4658.2009.07034.x 61   18 Cited 17 times in Scopus17 0
Pang, S. S., Duggleby, R. G. and Guddat, L. W. (2002) Crystal structure of yeast acetohydroxyacid synthase: A target for herbicidal inhibitors. Journal of Molecular Biology, 317 2: 249-262. doi:10.1006/jmbi.2001.5419 65   139 Cited 138 times in Scopus138 0
Schenk, Gerhard, Elliott, Tristan W., Leung, Eleanor, Carrington, Lyle E., Mitic, Natasa, Gahan, Lawrence R. and Guddat, Luke W. (2008) Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle. BMC Structural Biology, 8 6: 1-13. doi:10.1186/1472-6807-8-6 73   39 Cited 34 times in Scopus34 3
Guddat, L. W., Vos, S., Martin, J. L., Keough, D. T. and De Jersey, J. (2002) Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase. Protein Science, 11 7: 1626-1638. doi:10.1110/ps.0201002 90   21 Cited 20 times in Scopus20 0
Guddat, LW, Bardwell, JCA and Martin, JL (1998) Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization. Structure, 6 6: 757-767. doi:10.1016/S0969-2126(98)00077-X 78   118 3
Wang, Jian-Guo, Lee, Patrick K.-M., Dong, Yu-Hui, Pang, Siew Siew, Duggleby, Ronald G., Li, Zheng-Ming and Guddat, Luke W. (2009) Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. FEBS Journal, 276 5: 1282-1290. doi:10.1111/j.1742-4658.2009.06863.x 95   22 Cited 23 times in Scopus23 0
Pedroso, Marcelo M., Ely, Fernanda, Lonhienne, Thierry, Gahan, Lawrence R., Ollis, David L., Guddat, Luke W. and Schenk, Gerhard (2014) Determination of the catalytic activity of binuclear metallohydrolases using isothermal titration calorimetry. Journal of Biological Inorganic Chemistry, 19 3: 389-398. doi:10.1007/s00775-013-1079-0 48   1 Cited 1 times in Scopus1 0
Guddat, L (2011) Drug targets for the treatment of protozoan parasitic diseases. Current Topics in Medicinal Chemistry, 11 16: 2010-2011. 45   0 Cited 0 times in Scopus0
McCourt, J. A., Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2005) Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. Biochemistry, 44 7: 2330-2338. doi:10.1021/bi047980a 65   69 Cited 73 times in Scopus73 0
McCourt, J. A., Pang, S. S., King-Scott, J., Guddat, L. W. and Duggleby, R.G. (2005). Elucidation of the binding site for five sulfonylurea herbicides in Arabidopsis thaliana. In: 30th Annual Lorne Conference on Protein Structure and Function. 30th Annual Lorne Conference on Protein Structure and Function, Lorne, (Abstract). 6-11 Feb, 2005. 229  
McCourt, J. A., Tyagi, R., Guddat, L. W., Biou, V. and Duggleby, R. G. (2004) Facile crystallization of Escherichia coli ketol-acid reductoisomerase. Acta Crystallographica Section D-biological Crystallography, 60 1432-1434. doi:10.1107/S0907444904012247 81   3 Cited 3 times in Scopus3 0
McCourt, J. A., Pang, S. S., King-Scott, J., Guddat, L. W. and Duggleby, R. G. (2006) Herbicide-binding Sites Revealed in the Structure of Plant Acetohydroxyacid Synthase. Proceedings of The National Academy of Sciences of The United States of America, 103 3: 569-573. doi:10.1073/pnas.0508701103 74   129 Cited 135 times in Scopus135 3
Flanagan, J. U., Cassady, A. I., Schenk, G., Guddat, L. W. and Hume, D. A. (2006) Identification and molecular modeling of a novel, plant-like, human purple acid phosphatase. Gene, 377 1: 12-20. doi:10.1016/j.gene.2006.02.031 102   14 Cited 17 times in Scopus17 0
Hadler, K.ieran S., Huber, Thomas, Cassady, A. Ian, Weber, Jane, Robinson, Jodie, Burrows, Allan, Kelly, Gregory, Guddat, Luke W., Hume, David A., Schenk, Gerhard and Flanagan, Jack U. (2008) Identification of a non-purple tartrate-resistant acid phosphatase: An evolutionary link to Ser/Thr protein phosphatases?. BMC Research Notes, 1 1-8. doi:10.1186/1756-0500-1-78 78   Cited 3 times in Scopus3 0
Schenk, G., Ge, Y., Guddat, L., Carrington, L. E., Hume, D. A., Hamilton, S. E. and deJersey, J. (2000) Identification of mammalian-like purple acid phosphatases in a wide range of plants. Gene, 250 1-2: 117-125. doi:10.1016/S0378-1119(00)00186-4 55   79 Cited 89 times in Scopus89 0
Feder, Daniel, Hussein, Waleed M., Clayton, Daniel J., Kan, Meng-Wei, Schenk, Gerhard, McGeary, Ross P. and Guddat, Luke W. (2012) Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics. Chemical Biology and Drug Design, 80 5: 665-674. doi:10.1111/j.1747-0285.2012.12001.x 105   3 Cited 4 times in Scopus4 2
Keough, Dianne T., Hockova, Dana, Holy, Antonin, Naesens, Lieve M. J., Skinner-Adams, Tina S., de Jersey, John and Guddat, Luke W. (2009) Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutics. Journal of Medicinal Chemistry, 52 14: 4391-4399. doi:10.1021/jm900267n 77   38 Cited 37 times in Scopus37 0
McGeary, Ross P., Vella, Peter, Mak, Jeffery Y. W., Guddat, Luke W. and Schenk, Gerhard (2009) Inhibition of purple acid phosphatase with alpha-alkoxynaphthylmethylphosphonic acids. Bioorganic & Medicinal Chemistry Letters, 19 1: 163-166. doi:10.1016/j.bmcl.2008.10.125 88   16 Cited 17 times in Scopus17 0
Keough, Dianne T., Hocková, Dana, Rejman, Dominik, Spaček, Petr, Vrbková, Silvie, Krečmerová, Marcela, Eng, Wai Soon, Jans, Harmen, West, Nicholas P., Naesens, Lieve M. J., de Jersey, John and Guddat, Luke W. (2013) Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: potential for new antibacterial agents. Journal of Medicinal Chemistry, 56 17: 6967-6984. doi:10.1021/jm400779n 44   4 Cited 6 times in Scopus6 0
Elliott, T. W., Mitic, N., Gahan, L. R., Guddat, L. W. and Schenk, G. (2006) Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism. Journal of the Brazilian Chemical Society, 17 8: 1558-1565. doi:10.1590/S0103-50532006000800011 93   14 Cited 12 times in Scopus12 0
Batten, Stuart R., Kobe, Bostjan and Guddat, Luke (2014) International Year of Crystallography. Australian Journal of Chemistry, 67 12: 1718-1719. doi:10.1071/CH14557 5   0 0
Keough, Dianne T., Skinner-Adams, Tina, Jones, Malcolm K., Ng, Ai-Lin., Brereton, Ian M., Guddat, Luke W. and de Jersey, John (2006) Lead compounds for antimalarial chemotherapy: Purine base analogs discriminate between human and P-falciparum 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry, 49 25: 7479-7486. doi:10.1021/jm061012j 141   31 Cited 28 times in Scopus28 0
De Jersey, J., Zheng, Yuan-Zhi, Fan, H. K., Schenk, G., Guddat, L. and Hamilton, S. (2006) Mammalian-like purple acid phosphatases in plants. Chemical Research In Chinese Universities, 22 2: 263-264. doi:10.1016/S1005-9040(06)60093-7 77   0 0
Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2003) Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. Journal of Biological Chemistry, 278 9: 7639-7644. doi:10.1074/jbc.M211648200 149   120 Cited 120 times in Scopus120 0
Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2003). Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. In: East Coast Protein Meeting 2003. East Coast Protein Meeting, Coffs Harbour, (Poster). 27-29 June, 2003. 38  

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