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Thundyil, John, Pavlovski, Dale, Sobey, Christopher G. and Arumugam, Thiruma V. (2012) Adiponectin receptor signalling in the brain. British Journal of Pharmacology, 165 2: 313-327. doi:10.1111/j.1476-5381.2011.01560.x 84   31 Cited 35 times in Scopus35 0
Thiruma V. Arumugam, Terry M. Phillips, Aiwu Cheng, Christopher H. Morrell, Mark P. Mattson and Ruiqian Wan (2009) Age and energy intake interact to modify cell stress pathways and stroke outcome. Annals of Neurology, 67 1: 41-52. doi:10.1002/ana.21798 70   61 Cited 66 times in Scopus66 1
Dinh, Quynh N., Arumugam, Thiruma V., Young, Morag J., Drummond, Grant R., Sobey, Christopher G. and Chrissobolis, Sophocles (2012) Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke. Experimental and Translational Stroke Medicine, 4 1: 21.1-21.7. doi:10.1186/2040-7378-4-21 47 1 Cited 2 times in Scopus2 0
Woo, Ha-Na, Park, Jong-Sung, Gwon, A. Ryeong, Arumugam, Thiruma V. and Jo, Dong-Gyu (2009) Alzheimer's disease and Notch signaling. Biochemical and Biophysical Research Communications, 390 4: 1093-1097. doi:10.1016/j.bbrc.2009.10.093 147   41 Cited 38 times in Scopus38 0
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Newman, Michelle L., Ross, Paul A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2005) A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. International Immunopharmacology, 5 5: 883-892. doi:10.1016/j.intimp.2005.01.003 90   21 Cited 26 times in Scopus26 0
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2003) A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. Journal of Immunology, 171 10: 5514-5520. 96   74 Cited 75 times in Scopus75
Arumugam, T. V., Shiels, I. A., Strachan, A. J., Abbenante, G., Fairlie, D. P. and Taylor, S. M. (2003) A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats. Kidney International, 63 1: 134-142. doi:10.1046/j.1523-1755.2003.00737.x 116   101 Cited 108 times in Scopus108 0
Alfonso, Lloyd F., Srivenugopal, Kalkunte S., Arumugam, Thirua V., Abbruscato, Thomas J., Weidanz, Jon A. and Bhat, G. Jayarama (2009) Aspirin inhibits camptothecin-induced p21(CIP1) levels and potentiates apoptosis in human breast cancer cells. International Journal of Oncology, 34 3: 597-608. doi:10.3892/ijo_00000185 37   18 Cited 24 times in Scopus24 3
Rashid, Mamoon, Arumugam, Thiruma V. and Karamyan, Vardan T. (2010) Association of the novel non-AT(1), Non-AT(2) angiotensin binding site with neuronal cell death. Journal of Pharmacology And Experimental Therapeutics, 335 3: 754-761. doi:10.1124/jpet.110.171439 34   6 Cited 5 times in Scopus5 0
Chigurupati, Srinivasulu, Mughal, Mohamed R., Chan, Sic L., Arumugam, Thiruma V., Baharani, Akanksha, Tang, Sung-Chun, Yu, Qian-Sheng, Holloway, Harold W., Wheeler, Ross, Poosala, Suresh, Greig, Nigel H. and Mattson, Mark P. (2010) A synthetic uric acid analog accelerates cutaneous wound healing in mice. Plos One, 5 4: e10044-1-e10044 -10. doi:10.1371/journal.pone.0010044 87 1 6 Cited 4 times in Scopus4 0
Arumugam, Thiruma V., Okun, Eitan and Mattson, Mark P. (2010). Basis of ionic dysregulation in cerebral ischemia. In Lucio Ammunziato (Ed.), New strategies in stroke intervention: Ionic transporters, pumps, and new channels (pp. 1-11) New York, United States: Humana Press. doi:10.1007/978-1-60761-280-3_1 83 3 0
Thundyil, John, Pavlovski, Dale, Hsieh, Yu-Hsuan, Gelderblom, Mathias, Magnus, Tim, Fairlie, David P. and Arumugam, Thiruma V. (2012) C5a receptor (CD88) and TLR2 inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model. NeuroMolecular Medicine, 14 1: 30-39. doi:10.1007/s12017-012-8167-0 115   5 Cited 5 times in Scopus5 0
Thundyil, J., Pavlovski, D. and Arumugam, T., V (2012). C5a receptor (CD88) inhibition improves hypothermia-induced neuroprotection in an in vitro Ischemic Model. In: Abstracts of Stroke 2012 Conference - A combined event of the Stroke Society of Australasia 2012 Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference. Stroke 2012 Conference - A combined event of the Stroke Society of Australasia 2012 Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference, Sydney NSW Australia, (50-50). 29-31 August 2012. 26   0
Manzanero, Silvia, Gelderblom, Mathias, Magnus, Tim and Arumugam, Thiruma V. (2011) Calorie restriction and stroke. Experimental and Translational Stroke Medicine, 3 8.1-8.35. doi:10.1186/2040-7378-3-8 49   Cited 15 times in Scopus15 0
Park, Jong-Sung, Manzanero, Silvia, Chang, Jae-Woong, Choi, Yuri, Baik, Sang-Ha, Cheng, Yi-Lin, Li, Yu-I, Gwon, A-Ryeong, Woo, Ha-Na, Jang, Jiyeon, Choi, In-Young, Lee, Joo-Yong, Jung, Yong-Keun, Tang, Sung-Chun, Sobey, Christopher G., Arumugam, Thiruma V. and Jo, Dong-Gyu (2013) Calsenilin contributes to neuronal cell death in ischemic stroke. Brain Pathology, 23 4: 402-412. doi:10.1111/bpa.12013 62   1 Cited 2 times in Scopus2 0
Ishikawa, Mami, Vowinkel, Thorsten, Stokes, Karen Y., Arumugam, Thiruma V., Yilmaz, Gokhan, Nanda, Anil and Granger, D. Neil (2005) CD40/CD40 ligand signaling in mouse cerebral microvasculature after focal ischemia/reperfusion. Circulation, 111 13: 1690-1696. doi:10.1161/01.CIR.0000160349.42665.0C 44   56 Cited 68 times in Scopus68 0
Rajaram, Hemalatha, Palanivelu, Manoj Kumar, Arumugam, Thiruma V., Rao, Venkatesan M., Shaw, P. Nicholas, McGeary, Ross P. and Ross, Benjamin P. (2014) 'Click' assembly of glycoclusters and discovery of a trehalose analogue that retards A(beta)40 aggregation and inhibits A(beta)40-induced neurotoxicity. Bioorganic and Medicinal Chemistry Letters, 24 18: 4523-4528. doi:10.1016/j.bmcl.2014.07.077 91   1 Cited 0 times in Scopus0 1
Proctor, Lavinia M., Arumugam, Thiruma V., Shiels, Ian, Reid, Robert C., Fairlie, David P. and Taylor, Stephen M . (2004) Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury. British Journal of Pharmacology, 142 4: 756-764. doi:10.1038/sj.bjp.0705819 84   44 Cited 51 times in Scopus51 0
Arumugam, Thiruma V., Arnold, Naomi, Proctor, Lavinia M., Newman, Michelle, Reid, Robert C., Hansford, Karl A., Fairlie, David P., Shiels, Ian A. and Taylor, Stephen M. (2003) Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British Journal of Pharmacology, 140 1: 71-80. doi:10.1038/sj.bjp.0705402 94   30 Cited 32 times in Scopus32 0
Arumugam, Thiruma V., Magnus, Tim, Woodruff, Trent M., Proctor, Lavinia M., Shiels, Ian A., Taylor, Stephen M., A. H. Wu and J. Delanghe (2006) Complement mediators in ischemia-reperfusion injury. Clinica Chimica Acta, 374 1-2: 33-45. doi:10.1016/j.cca.2006.06.010 68   60 Cited 64 times in Scopus64 0
Choi, Yun-Hyung, Gwon, A-Ryeong, Jeong, Hye-Young, Park, Jong-Sung, Baik, Sang-Ha, Arumugam Thiruma V. and Jo, Dong-Gyu (2010) Contribution of gamma-secretase to calcium-mediated cell death. Neuroscience Letters, 469 3: 425-428. doi:10.1016/j.neulet.2009.12.043 63   4 Cited 5 times in Scopus5 0
Arumugam, TV, Salter, JW, Chidlow, JH, Ballantyne, CM, Kevil, CG and Granger, DN (2004) Contributions of LFA-1 and Mac-1 to brain injury and microvascular dysfunction induced by transient middle cerebral artery occlusion. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 287 6: H2555-H2560. doi:10.1152/ajpheart.00588.2004 26   49 Cited 59 times in Scopus59 0
Stranahan, Alexis M., Arumugam, Thiruman V., Cutler, Roy G., Lee, Kim, Egan, Josephine M. and Mattson, Mark P. (2008) Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nature Neuroscience, 11 3: 309-317. doi:10.1038/nn2055 34   235 Cited 237 times in Scopus237 1
Mughal, Mohamed R., Baharani, Akanksha, Chigurupati, Srinivasulu, Son, Tae Gen, Chen, Edmund, Yang, Peter, Okun, Eitan, Arumugam, Thiruma, Chan, Sic L. and Mattson, Mark P. (2011) Electroconvulsive shock ameliorates disease processes and extends survival in huntingtin mutant mice. Human Molecular Genetics, 20 4, Article number ddq512: 659-669. doi:10.1093/hmg/ddq512 37   7 Cited 7 times in Scopus7 1
Cheng Y.-L., Choi Y., Sobey C.G., Arumugam T.V. and Jo D.-G. (2015) Emerging roles of the γ-secretase-notch axis in inflammation. Pharmacology and Therapeutics, 147 80-90. doi:10.1016/j.pharmthera.2014.11.005 7   0 Cited 0 times in Scopus0 0
Coulthard, Mark G., Morgan, Michael, Woodruff, Trent M., Arumugam, Thiruma V., Taylor, Stephen M., Carpenter, Todd C., Martin Lackmann, and Boyd, Andrew W. (2012) Eph/Ephrin signaling in injury and inflammation. American Journal of Pathology, 181 5: 1493-1503. doi:10.1016/j.ajpath.2012.06.043 79   15 Cited 17 times in Scopus17 0
Tang, Sung-Chun, Yeh, Shin-Joe, Li, Yu-I, Wang Yu-Chi, Baik, Sang-Ha, Santro, Tomislav, Widiapradja, Alexander, Manzanero, Silvia, Sobey, Christopher G., Jo, Dong-Gyu, Arumugam, Thiruma V. and Jeng, Jiann-Shing (2013) Evidence for a detrimental role of TLR8 in ischemic stroke. Experimental Neurology, 250 341-347. doi:10.1016/j.expneurol.2013.10.012 21   4 Cited 5 times in Scopus5 6
Okun, Eitan, Barak, Boaz, Saada-Madar, Ravit, Rothman, Sarah M., Griffioen, Kathleen J., Roberts, Nicholas, Castro, Kamilah, Mughal, Mohamed R., Pita, Mario A., Stranahan, Alexis M., Arumugam, Thiruma V. and Mattson, Mark P. (2012) Evidence for a developmental role for TLR4 in learning and memory. PLoS One, 7 10 Article No.e47522: . doi:10.1371/journal.pone.0047522 20   14 Cited 12 times in Scopus12 2
Thundyil, John, Tang, Sung-Chun, Okun, Eitan, Shah, Kausik, Karamyan, Vardan T., Li , Yu-I, Woodruff, Trent M., Taylor, Stephen M., Jo, Dong-Gyu, Mattson, Mark P and Arumugam, Thiruma V. (2010) Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death. Experimental and Translational Stroke Medicine, 2 1: 15-1-15-8. doi:10.1186/2040-7378-2-15 56   Cited 17 times in Scopus17 0
Cheng, Yi-Lin, Park, Jong-Sung, Manzanero, Silvia, Choi, Yuri, Baik, Sang-Ha, Okun, Eitan, Gelderblom, Mathias, Fann, David Yang-Wei, Magnus, Tim, Launikonis, Bradley S., Mattson, Mark P., Sobey, Christopher G., Jo, Dong-Gyu and Arumugam, Thiruma V. (2014) Evidence that collaboration between HIF-1alpha and Notch-1 promotes neuronal cell death in ischemic stroke. Neurobiology of Disease, 62 286-295. doi:10.1016/j.nbd.2013.10.009 50   5 Cited 5 times in Scopus5 0
Arumugam, Thiruma V., Cheng, Yi-Lin, Choi, Yuri, Choi, Yun-Hyung, Yang, Sunghee, Yun, Young-Kwang, Park, Jong-Sung, Yang, Dong Kwon, Thundyil, John, Gelderblom, Mathias, Karamyan, Vardan T., Tang, Sung-Chun, Chan, Sic L., Magnus, Tim, Sobey, Christopher G. and Jo, Dong-Gyu (2011) Evidence that {gamma}-Secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-{kappa}B-Bcl-2-interacting mediator of cell death pathway in ischemic stroke. Molecular Pharmacology, 80 1: 23-31. doi:10.1124/mol.111.071076 44   21 Cited 25 times in Scopus25 0
Jo, Dong-Gyu, Arumugam, Thiruma V., Woo, Ha-Na, Park, Jong-Sung, Tang, Sung-Chun, Mughal, Mohamed, Hyun, Dong-Hoon, Park, Jun-Hyung, Choi, Yun-Hyung, Gwon, A-Ryeong, Camandola, Simonetta, Cheng, Aiwu, Cai, Huaibin, Song, Weihong, Markesbery, William R. and Mattson, Mark P. (2010) Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease. Neurobiology of Aging, 31 6: 917-925. doi:10.1016/j.neurobiolaging.2008.07.003 90 8 30 Cited 30 times in Scopus30 0
Cheng, Yi-Lin, Choi, Yuri, Seow, Wei Lun, Manzanero, Silvia, Sobey, Christopher G., Jo, Dong-Gyu and Arumugam, Thiruma V. (2014) Evidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress. Brain Research, 1586 193-202. doi:10.1016/j.brainres.2014.08.054 25   0 Cited 0 times in Scopus0 1
Magnus, Tim, Coksaygan, Turhan, Korn, Thomas, Xue, Haipeng, Arumugam, Thiruma V., Mughal, Mohamed R., Eckley, D. Mark, Tang, Sung-Chun, DeTolla, Louis, Rao, Mahendra S., Cassiani-Ingoni, Riccardo and Mattson, Mark P. (2007) Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes. Journal of Neuroscience Research, 85 10: 2126-2137. doi:10.1002/jnr.21368 68   53 Cited 53 times in Scopus53 0
Thundyil, John, Manzanero, Silvia, Pavlovski, Dale, Cully, Tanya R., Lok, Ker-Zhing, Widiapradja, Alexander, Chunduri, Prasad, Jo, Dong-Gyu, Naruse, Chie, Asano, Masahide, Launikonis, Bradley S., Sobey, Christopher G., Coulthard, Mark G. and Arumugam, Thiruma V. (2013) Evidence that the EphA2 receptor exacerbates ischemic brain injury. PLoS One, 8 1: e53528.1-e53528.8. doi:10.1371/journal.pone.0053528 86   5 Cited 6 times in Scopus6 2
Tang, Sung-Chun, Wang, Yu-Chi, Li, Yu-I, Lin, Hsiao-Ching, Manzanero, Silvia, Hsieh, Yu-Hsuan, Phipps, Simon, Hu, Chaur-Jong, Chiou, Hung-Yi, Huang, Yi-Shuian, Yang, Wei-Shiung, Mattson, Mark P., Arumugam, Thiruma V. and Jeng, Jiann-Shing (2013) Functional role of soluble receptor for advanced glycation end products in stroke. Arteriosclerosis Thrombosis and Vascular Biology, 33 3: 585-594. doi:10.1161/ATVBAHA.112.300523 43   15 Cited 16 times in Scopus16 1
Arumugam, Thiruma V., Chan, Sic L., Jo, Dong-Gyu, Yilmaz, Gokhan, Tang, Sung-Chun, Cheng, Aiwu, Gleichmann, Marc, Okun, Eitan, Dixit, Vishwa D., Chigurupati, Srinivasulu, Mughal, Mohamed R., Ouyang, Xin, Miele, Lucio, Magnus, Tim, Poosala, Suresh, Granger, D. Neil and Mattson, Mark P. (2006) Gamma secretase-mediated notch signaling worsens brain damage and functional outcome in ischemic stroke. Nature Medicine, 12 6: 621-623. doi:10.1038/nm1403 67   110 Cited 112 times in Scopus112 0
Carroll, Anthony R., Arumugan, Garrie, Quinn, Ronald J., Redburn, Joanne, Guymer, Gordon and Grimshaw, Paul (2005) Grandisine A and B, novel indolizidine alkaloids with human delta-opioid receptor binding affinity from the leaves of the Australian rainforest tree Elaeocarpus grandis. Journal of Organic Chemistry, 70 5: 1889-1892. doi:10.1021/jo048525n 33   28 Cited 31 times in Scopus31 0
Carroll, Anthony R., Arumugan, Thirumavalavan, Redburn, Joanne, Ngo, Ana, Guymer, Gordon P., Forster, Paul I. and Quinn, Ronald J. (2010) Hasubanan alkaloids with delta-opioid binding affinity from the aerial parts of Stephania japonica. Journal of Natural Products, 73 5: 988-991. doi:10.1021/np100009j 39   6 Cited 8 times in Scopus8 0
Cheng, Y. L., Sobey, C. G., Jo, D. G. and Arumugam, T., V (2012). HIF-1 alpha and NOTCH interaction mediates ischaemic-stroke induced neuronal death. In: Abstracts of Stroke 2012 Conference - A combined event of the Stroke Society of Australasia 2012 Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference. Stroke 2012 Conference - A combined event of the Stroke Society of Australasia 2012 Annual Scientific Meeting and the 8th Smart Strokes Australasian Nursing and Allied Health Stroke Conference, Sydney NSW Australia, (19-20). 29-31 August 2012. 54   0
Arumugam, Thiruma V., Gleichmann, Marc, Tang, Sung-Chun and Mattson, Mark P. (2006) Hormesis/preconditioning mechanisms, the nervous system and aging. Ageing Research Reviews, 5 2: 165-178. doi:10.1016/j.arr.2006.03.003 48   70 Cited 71 times in Scopus71 0
Worthington, Rebecca A., Arumugam, Thiruma V., Hansen, Mitchell A., Balcar, Vladimir J. and Barden, Julian A. (1998). Identification and localisation of ATP P(2X) receptors in rat midbrain. In: 5th Annual Meeting of the Australian-Electrophoresis-Society, North Ryde, NSW, Australia, (2077-2080). 15-16 October 1998. doi:10.1002/(SICI)1522-2683(19990701)20:10<2077::AID-ELPS2077>3.0.CO;2-0 32   24 Cited 21 times in Scopus21 0
Chu, Hannah X., Kim, Hyun A., Lee, Seyoung, Moore, Jeffrey P., Chan, Christopher T., Vinh, Antony, Gelderblom, Mathias, Arumugam, Thiruma V., Broughton, Brad R. S., Drummond, Grant R. and Sobey, Christopher G. (2014) Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism, 34 3: 450-459. doi:10.1038/jcbfm.2013.217 13   8 Cited 6 times in Scopus6 0
Chigurupati, Srinivasulu, Arumugam, Tiruma V., Jameel, Shafaq, Mughal, Mohamed R., Mattson, Mark P. and Poosala, Suresh (2007). Impaired notch signaling significantly delays wound healing. In: Abstracts of the 17th Annual Meeting of the Wound Healing Society, Tampa, FL, United States, (A43-A43). 28 April-1 May 2007. 33   0
Brait, Vanessa H., Arumugam, Thiruma V., Drummond, Grant R. and Sobey, Christopher G. (2012) Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism, 32 4: 598-611. doi:10.1038/jcbfm.2012.6 27   44 Cited 49 times in Scopus49 0
Manzanero, Silvia, Erion, Joanna R., Santro, Tomislay, Steyn, Frederik J., Chen, Chen, Arumugam, Thiruma V. and Stranahan, Alexis M. (2014) Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery. Journal of Cerebral Blood Flow and Metabolism, 34 5: 897-905. doi:10.1038/jcbfm.2014.36 24   2 Cited 1 times in Scopus1 2
Fann, David Yang Wei, Santro, Tomislav, Manzanero, Silvia, Widiapradja, Alexander, Cheng, Yi-Lin, Lee, Seung-Yoon, Chunduri, Prasad, Jo, Dong-Gyu, Stranahan, Alexis M., Mattson, Mark P. and Arumugam, Thiruma V. (2014) Intermittent fasting attenuates inflammasome activity in ischemic stroke. Experimental Neurology, 257 114-119. doi:10.1016/j.expneurol.2014.04.017 51   1 Cited 1 times in Scopus1 2
Manzanero, S., Wosiski-Kuhn, M., Erion, J., Santro, T., Arumugam, T. and Stranahan, A. (2013). Intermittent fasting improves ischemic stroke outcome and modifies post-stroke neurogenesis and synaptic plasticity in mice. In: Special Issue: STROKE 2013 CONFERENCE. 24th Annual Scientific Meeting of the Stroke Society of Australia.. 24th Annual Scientific Meeting of the Stroke Society of Australia., Darwin, NT Australia, (50-50). 31 July-2 August 2013. doi:10.1111/ijs.12143 102   0 0
Hsieh, Yu-Hsuan, McCartney, Kieran, Moore, Tyson A., Thundyil, John, Gelderblom, Mathias, Manzanero, Silvia and Arumugam, Thiruma V. (2011) Intestinal ischemia reperfusion injury leads to inflammatory changes in the brain. Shock, 36 4: 424-430. doi:10.1097/SHK.0b013e3182295f91 78   11 Cited 11 times in Scopus11 2
Arumugam, TV, Tang, SC, Mughal, MR, Chan, SL, Mattson, MP and Basta, M (2007). Intravenous immunoglobulin (IVIG) ameliorates ischmia/reperfusion-induced brain injury in mice. In: Molecular Immunology. 21st International Complement Workshop, Beijing Peoples R China, (150-151). Oct 22-26, 2006. doi:10.1016/j.molimm.2006.07.014 18   0 0

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