Browse by all authors Browse By Author ID - Megan O'Mara

Browse Results (46 results found)

Subscribe to the RSS feed for this result setSubscribe to the RSS feed for this result set

Refine

  Abstract Views File Downloads Thomson Reuters Web of Science Citation Count Scopus Citation Count Altmetric Score
Jones, Peter M., O'Mara, Megan L. and George, Anthony M. (2009) ABC transporters: A riddle wrapped in a mystery inside an enigma. Trends in Biochemical Sciences, 34 10: 520-531. doi:10.1016/j.tibs.2009.06.004 156   86 Cited 83 times in Scopus83 0
Plumptre, Charles D., Eijkelkamp, Bart A., Morey, Jacqueline R., Behr, Felix, Couñago, Rafael M., Ogunniyi, Abiodun D., Kobe, Bostjan, O'Mara, Megan L., Paton, James C. and McDevitt, Christopher A. (2014) AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae. Molecular Microbiology, 91 4: 834–851-834–851. doi:10.1111/mmi.12504 26   7 Cited 7 times in Scopus7 0
O'Mara, Megan, Barry, Peter H. and Chung, Shin-Ho (2003) A model of the glycine receptor deduced from Brownian dynamics studies. Proceedings of the National Academy of Sciences of the United States of America, 100 7: 4310-4315. doi:10.1073/pnas.0630652100 75   Cited 23 times in Scopus23 0
O'Mara, M, Barry, PH and Chung, SH (2003) A model of the glycine receptor deduced from Brownian dynamics studies. Proceedings of the National Academy of Sciences of the United States of America, 100 7: 4310-4315. doi:10.1073/pnas.0630652100 21   22 Cited 23 times in Scopus23 0
Brooks, Andrew J, Chhabra, Yash, Abankwa, Daniel, O’Mara, Megan, Dai, Wei, Gardon, Olivier, Tunny, Kathryn A., Blucher, Kristopher M., Morton, Craig J., Parker, Michael W., Sierecki, Emma, Gambin, Yann, Guillermo A. Gomez, Alexandrov, Kirill Kirill, Doxastakis, Manolis, Mark, Alan E. and Waters, Michael J. (2014). A new cytokine receptor activation paradigm: Activation of JAK2 by the growth hormone receptor. In: SI: 2014 ICIS Abstract Issue, ICIS Conference. 2nd Annual Meeting of the International Cytokine and Interferon Society (ICIS), Melbourne, VIC Australia, (22-22). 26 - 29 October 2014. doi:10.1016/j.cyto.2014.07.227 29   0 0
Moussatova, Anastassiia, Kandt, Christian, O'Mara, Megan L. and Tieleman, D. Peter (2008) ATP-binding cassette transporters in Escherichia coli. BBA: Biomembranes, 1778 9: 1757-1771. doi:10.1016/j.bbamem.2008.06.009 52   41 Cited 41 times in Scopus41 0
Sowa, Anna, Harrison, Michael, Tregaskes, Clive, Chappell, Paul, Roversi, Pietro, Lea, Susan, O'Mara, Megan, Gaudet, Rachelle and Kaufman, Jim (2012). Chicken TAP genes are polymorphic and co-evolve with the dominantly-expressed class I gene. In: 7th International EMBO Workshop on Antigen Presentation and Processing. 7th Biannual Workshop on Antigen Presentation, Amsterdam, Netherlands, (19-20). 24-27 April 2012. doi:10.1016/j.molimm.2012.02.050 187   0 0
Oloo, Eliud, Kandt, Christian, O’Mara, Megan L. and Tieleman, D. Peter (2006). Computer simulations of ABC transporter components. In: Proceedings and Abstracts of the 49th Annual Canadian Society of Biochemistry and Molecular and Cellular Biology (CSBMCB) Meeting. 49th Annual Canadian Society of Biochemistry and Molecular and Cellular Biology Meeting, Ontario, Canada, (900-911). 31 May- 4 June 2006. doi:10.1139/O06-182 62   7 Cited 8 times in Scopus8 0
Corry, B, O'Mara, M and Chung, SH (2004) Conduction mechanisms of chloride ions in ClC-type channels. Biophysical Journal, 86 2: 846-860. 13   58
Corry, Ben, O’Mara, Megan and Chung, Shin-Ho (2004) Conduction mechanisms of chloride ions in ClC-type channels. Biophysical Journal, 86 846-860. doi:10.1016/S0006-3495(04)74160-0 40   Cited 58 times in Scopus58 0
Storm, Janet, Modok, Szabolcs, O’Mara, Megan L., Tieleman, D. Peter, Kerr, Ian D. and Callaghan, Richard (2008) Cytosolic region of TM6 in P-Glycoprotein: Topographical analysis and functional perturbation by site directed labeling. Biochemistry, 47 12: 3615-3624. doi:10.1021/bi7023089 53   11 Cited 11 times in Scopus11 0
O'Mara, M. L. and Tieleman, D. P. (2007). Determining the structural conformation of P-glycoprotein via homology modelling. In: 51st Annual Meeting of the Biophysical-Society, Baltimore, United States, (564A-564A). 3-7 March 2007. 72   0
Xue, Ying, O'Mara, Megan L., Surawski, Peter P. T., Trau, Matt and Mark, Alan E. (2011) Effect of poly(ethylene glycol) (PEG) spacers on the conformational properties of small peptides: A molecular dynamics study. Langmuir, 27 1: 296-303. doi:10.1021/la103800h 119   10 Cited 11 times in Scopus11 0
Jia, Z. G., O'Mara, M. L., Zuegg, J., Matthew Cooper and Mark, Alan (2013) Erratum: The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II (Biophysical Journal (2011) 101 (2684-2692)). Biophysical Journal, 104 2: 516-516. doi:10.1016/j.bpj.2012.12.031 94   0 Cited 0 times in Scopus0 0
O'Mara, Megan, Cromer, Brett, Parker, Michael and Chung, Shin-Ho (2005) Homology model of the GABAA receptor examined using Brownian Dynamics. Biophysical Journal, 88 5: 3286-3299. doi:10.1529/biophysj.104.051664 47   46 Cited 47 times in Scopus47 0
Couñago, Rafael M., Ween, Miranda P., Begg, Stephanie L., Bajaj, Megha, Zuegg, Johannes, O'Mara, Megan L., Cooper, Matthew A., McEwan, Alastair G., Paton, James C., Kobe, Bostjan and McDevitt, Christopher A. (2014) Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology, 10 1: 35-41. doi:10.1038/nCHeMBIO.1382 69 3 12 Cited 15 times in Scopus15 123
Fairweather, Stephen J., Broer, Angelika, O'Mara, Megan L. and Broer, Stefan (2012) Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1. Biochemical Journal, 446 1: 135-148. doi:10.1042/BJ20120307 72   8 Cited 9 times in Scopus9 1
O'Mara, Megan L., Yin, Jian, Hoyles, Matthew and Chung, Shin-Ho (2006). Investigating the mechanism of proton transfer through the bacterial ClC transporter. In: Biophysical Journal : Annual Meeting Abstracts of the Biophysical Society Meeting. 50th Annual Meeting of the Biopysical-Society, Salt Lake City, Utah, U.S.A., (2791-2791). 18-22 February, 2006. 28  
O’Mara, M., Oakley, A. and Bröer, S. (2006) Mechanism and putative structure of B0-like neutral amino acid transporters. Journal of Membrane Biology, 213 2: 111-118. doi:10.1007/s00232-006-0879-3 54   12 Cited 12 times in Scopus12 0
Brooks, Andrew J., Dai, Wei, O’Mara, Megan L., Abankwa, Daniel, Chhabra, Yash, Pelekanos, Rebecca A., Gardon, Olivier, Tunny, Kathryn A., Blucher, Kristopher M., Morton, Craig J., Parker, Michael W., Sierecki, Emma, Gambin, Yann, Gomez, Guillermo A., Alexandrov, Kirill, Wilson, Ian A., Doxastakis, Manolis, Mark, Alan E. and Waters, Michael J. (2014) Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. Science, 344 6185: 1249783.1-1249783.12. doi:10.1126/science.1249783 155   25 Cited 21 times in Scopus21 36
O'Mara, Megan, Keramidas, Angelo, Barry, Peter H. and Chung, Shin-Ho (2003). Mechanism of ion permeation in the glycine receptor and its cation-selective mutations. In: Biophysical Journal: 47th Annual Meeting Abstracts. 47th Annual Meeting of the Biophysical Society, San Antonio, Texas, (93a-93a). 1-5 March 2003. 37   Cited 0 times in Scopus0
O'Mara, M, Keramidas, A, Barry, PH and Chung, SH (2003). Mechanism of ion permeation in the glycine receptor and its cation-selective mutations. In: Biophysical Journal. 47th Annual Meeting of the Biophysical-Society, San Antonio Texas, (93A-93A). Mar 01-05, 2003. 21   0
Corry, B., O'Mara, M., Bisset, D. and Chung, S. H. (2004). Mechanisms of chloride conduction in ClC channels. In: Biophysical Journal. 48th Annual Meeting of the Biophysical Society, Baltimore, Maryland, USA, (5a-5a). 14-18 February 2004. 35   Cited 0 times in Scopus0
Corry, B, O'Mara, M, Bisset, D and Chung, SH (2004). Mechanisms of chloride conduction in ClC channels. In: Biophysical Journal. 48th Annual Meeting of the Biophysical Society, Baltimore Md, (5A-5A). Feb 14-18, 2004. 21   0
Schmidt, Thomas H., O’Mara, Megan L. and Kandt, Christian (2012) Molecular dynamics simulations of membrane proteins: building starting structures and example applications. Current Physical Chemistry, 2 4: 363-378. 197 2
Klassen, Tara L., O'Mara, Megan L., Redstone, Megan, Spencer, Andrew N. and Gallin, Warren J. (2008) Non-linear intramolecular interactions and voltage sensitivity of a KV1 family potassium channel from Polyorchis penicillatus (Eschscholtz 1829). Journal of Experimental Biology, 211 21: 3442-3453. doi:10.1242/jeb.022608 55   5 Cited 4 times in Scopus4 0
McArthur, J. R., Singh, G., O'Mara, M. L., McMaster, D., Ostroumov, V., Tieleman, D. P. and French, R. J. (2011) Orientation of mu-conotoxin PIIIA in a sodium channel vestibule, based on voltage dependence of its binding. Molecular Pharmacology, 80 2: 219-227. doi:10.1124/mol.111.071779 46   11 Cited 11 times in Scopus11 0
Corry, Ben, O'Mara, Megan and Chung, Shin-Ho (2004) Permeation dynamics of chloride ions in the ClC-0 and ClC-1 channels. Chemical Physics Letters, 386 4-6: 233-238. doi:10.1016/j.cplett.2004.01.072 46   7 Cited 7 times in Scopus7 0
O'Mara, Megan L. and Tieleman, D. Peter (2007) P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK. FEBS Letters, 581 22: 4217-4222. doi:10.1016/j.febslet.2007.07.069 39   69 Cited 71 times in Scopus71 0
O'Mara, Megan and Deplazes, Evelyne (2014). Polypeptide and protein modeling for drug design. In Dieter Jaeger and Ranu Jung (Ed.), Encyclopedia of computational neuroscience (pp. xx-xx) Berlin, Germany: Springer. doi:10.1007/SpringerReference_349045 53   0
Storm, Janet, O’Mara, Megan L., Crowley, Emily H., Peall, Jonathan, Tieleman, D. Peter, Kerr, Ian D. and Callaghan, Richard (2007) Residue G346 in transmembrane segment six is involved in inter-domain communication in P-Glycoprotein. Biochemistry, 46 35: 9899-9910. doi:10.1021/bi700447p 44   28 Cited 29 times in Scopus29 0
O'Mara, M. L., Cromer, B. A., Parker, M. W. and Chung, S. H. (2005). Simulations of ion permeation through a homology model of the GABA(A) receptor. In: Biophysical Journal : Annual Meeting Abstracts of the Biophysical Society Meeting. 49th Annual Meeting of the Biopysical-Society, Long Beach, California, U.S.A., (150A-150A). 12-16 February, 2005. 34  
O'Mara, ML, Cromer, BA, Parker, MW and Chung, SH (2005). Simulations of ion permeation through a homology model of the GABA(A) receptor. In: Biophysical Journal. 49th Annual Meeting of the Biopysical-Society, Long Beach Ca, (150A-150A). Feb 12-16, 2005. 19   2
Oancea, Giani, O'Mara, Megan L., Bennett, W. F. Drew, Tieleman, D. Peter, Abele, Rupert and Tampé, Robert (2009) Structural arrangement of the transmission interface in the antigen ABC transport complex TAP. National Academy of Sciences. Proceedings, 106 14: 5551-5556. doi:10.1073/pnas.0811260106 35   52 Cited 50 times in Scopus50 0
O'Mara, Megan L. and Mark, Alan E. (2014) Structural characterization of two metastable ATP-bound states of P-glycoprotein. PLoS One, 9 3: e91916.1-e91916.14. doi:10.1371/journal.pone.0091916 72   1 Cited 1 times in Scopus1 0
Lawson, J., O'Mara, M. L. and Kerr, I. D. (2008) Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein. BBA: Biomembranes, 1778 2: 376-391. doi:10.1016/j.bbamem.2007.10.021 52   17 Cited 16 times in Scopus16 0
van Wonderen, Jessica H., McMahon, Róisin M., O'Mara, Megan L., McDevitt, Christopher A., Thomson, Andrew J., Kerr, Ian D., MacMillan, Fraser and Callaghan, Richard (2014) The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis. FEBS Journal, 281 9: 2190-2201. doi:10.1111/febs.12773 25   2 Cited 4 times in Scopus4 1
Jia, ZhiGuang, O'Mara, Megan L., Zuegg, Johannes, Cooper, Matthew A. and Mark, Alan E. (2011) The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II. Biophysical Journal, 101 11: 2684-2692. doi:10.1016/j.bpj.2011.10.047 110   7 Cited 6 times in Scopus6 0
O’Mara, Megan L. and Mark, Alan E. (2012) The effect of environment on the structure of a membrane protein: P-glycoprotein under physiological conditions. Journal of Chemical Theory and Computation, 8 10: 3964-3976. doi:10.1021/ct300254y 118   9 Cited 8 times in Scopus8 1
Procko, Erik, O'Mara, Megan L., Bennett, W. F. Drew, Tieleman, D. Peter and Gaudet, Rachelle (2009) The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter. FASEB Journal, 23 5: 1287-1302. doi:10.1096/fj.08-121855 47   62 Cited 60 times in Scopus60 0
Barry, P. H. and O'Mara, M. L. (2005). The reliability of relative cation-anion permeabilities deduced from reversal (dilution) potential measurements in ion channel studies, and Brownian dynamics predictions. In: FASEB Journal. Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego, California, U.S.A., (A1170-A1170). 31 March, - April, 2005. 37  
Barry, PH and O'Mara, ML (2005). The reliability of relative cation-anion permeabilities deduced from reversal (dilution) potential measurements in ion channel studies, and Brownian dynamics predictions. In: Faseb Journal. Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego Ca, (A1170-A1170). Mar 31-Apr 06, 2005. 26   1
Chen, Wenqian, Wang, Ruiwu, Chen, Biyi, Zhong, Xiaowei, Kong, Huihui, Bai, Yunlong, Zhou, Qiang, Xie, Cuihong, Zhang, Jingqun, Guo, Ang, Tian, Xixi, Jones, Peter P., O'Mara, Megan L., Liu, Yingjie, Mi, Tao, Zhang, Lin, Bolstad, Jeff, Semeniuk, Lisa, Cheng, Hongqiang, Zhang, Jianlin, Chen, Ju, Tieleman, D. Peter, Gillis, Anne M., Duff, Henry J., Fill, Michael, Song, Long-Sheng and Chen, S. R. Wayne (2014) The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias. Nature Medicine, 20 2: 184-192. doi:10.1038/nm.3440 25   15 Cited 15 times in Scopus15 110
Crowley, Emily, O'Mara, Megan L., Reynolds, Catherine, Tieleman, D. Peter, Storm, Janet, Kerr, Ian D. and Callaghan, Richard (2009) Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1. Biochemistry, 48 26: 6249-6258. doi:10.1021/bi900373x 28   12 Cited 13 times in Scopus13 0
Crowley, Emily, O'Mara, Megan L., Kerr, Ian D. and Callaghan, Richard (2010) Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1. Febs Journal, 277 19: 3974-3985. doi:10.1111/j.1742-4658.2010.07789.x 49 1 13 Cited 13 times in Scopus13 0
Jia, ZhiGuang, O'Mara, Megan L., Zuegg, Johannes, Cooper, Matthew A. and Mark, Alan E. (2013) Vancomycin: ligand recognition, dimerization and super-complex formation. FEBS Journal, 280 5: 1294-1307. doi:10.1111/febs.12121 117   2 Cited 3 times in Scopus3 1