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Reid, Robert C., Abbenante, Giovanni, Taylor, Stephen M. and Fairlie, David P. (2003) A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug. Journal of Organic Chemistry, 68 11: 4464-4471. doi:10.1021/jo034228r 232   33 Cited 33 times in Scopus33 0
Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). Alpha helix induction in HIV REV34-50 by N-terminal nucleators. In: Chemical Engineering News: Abstracts-232nd ACS National Meeting. 232nd ACS National Meeting, San Francisco, CA, U.S.A., (55-55). 10-14 September, 2006. doi:10.1021/cen-v084n034.p055 45   0
Iyer, Abishek, Lim, Junxian, Poudyal, Hemant, Reid, Robert C., Suen, Jacky Y., Webster, Julie, Prins, Johannes B., Whitehead, Jonathan P., Fairlie, David P. and Brown, Lindsay (2012) An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats. Diabetes, 61 9: 2320-2329. doi:10.2337/db11-1179 82 3 6 Cited 7 times in Scopus7 1
Reid, Robert C., March, Darren R., Dooley, Michael J., Bergman, Doug A., Abbenante, Giovanni and Fairlie, David P. (1996) A novel bicyclic enzyme inhibitor as a consensus peptidomimetic for the receptor-bound conformations of 12 peptidic inhibitors of HIV-1 protease. Journal of The American Chemical Society, 118 36: 8511-8517. doi:10.1021/ja960433v 74   42 Cited 35 times in Scopus35 0
Reid, R. C., Abbenante, G., March, D. R., Scanlon, M. and Fairlie, D. P. (1997) A novel strategy for the design of potent peptidomimetic inhibitors of proteolytic enzymes: Application to HIV-1 protease.. Abstracts of Papers of The American Chemical Society, 214 177-MEDI. 73   0
Woodruff, Trent M., Strachan, Anna J., Dryburgh, Nathan, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002) Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat. Arthritis and Rheumatism, 46 9: 2476-2485. doi:10.1002/art.10449 98   75 Cited 73 times in Scopus73 0
Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006) Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 11: 7000-7007. 123   17 Cited 19 times in Scopus19
Iyer, Abishek, Fenning, Andrew, Lim, Junxian, Le, Giang T, Reid, Robert C, Halili, Maria A, Fairlie, David P and Brown, Lindsay (2010) Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats. British Journal of Pharmacology, 159 7: 1408-1417. doi:10.1111/j.1476-5381.2010.00637.x 137   35 Cited 44 times in Scopus44 0
Wheatley, Nicole C., Andrews, Katherine T., Tran, Truc L., Lucke, Andrew J., Reid, Robert C. and Fairlie, David P. (2010) Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components. Bioorganic & Medicinal Chemistry Letters, 20 23: 7080-7084. doi:10.1016/j.bmcl.2010.09.096 117   15 Cited 15 times in Scopus15 0
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Newman, Michelle L., Ross, Paul A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2005) A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. International Immunopharmacology, 5 5: 883-892. doi:10.1016/j.intimp.2005.01.003 89   21 Cited 26 times in Scopus26 0
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2003) A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. Journal of Immunology, 171 10: 5514-5520. 90   72 Cited 72 times in Scopus72
Alewood, Dianne, Hopping, Gene, Brust, Andreas, Reid, Robert C. and Alewood, Paul F. (2010) Benzhydrylamine linker grafting: A strategy for the improved synthesis of C-terminal peptide amides. Journal of Peptide Science, 16 10: 551-557. doi:10.1002/psc.1248 69 1 3 Cited 2 times in Scopus2 0
Glenn, MP, Pattenden, LK, Reid, RC, Tyssen, DP, Tyndall, JDA, Birch, CJ and Fairlie, DP (2002) beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activity. Journal of Medicinal Chemistry, 45 2: 371-381. doi:10.1021/jm010414i 113   43 Cited 45 times in Scopus45 0
Liu, Junxian, Iyer, Abishek, Suen, Jacky Y., Seow, Vernon, Reid, Robert C., Brown, Lindsay and Fairlie, David P. (2013) C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling. The FASEB Journal, 27 2: 822-831. doi:10.1096/fj.12-220582 55   22 Cited 24 times in Scopus24 2
Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2008) Clean Or dirty - Just how selective do drugs need to be?. Australian Journal of Chemistry, 61 9: 654-660. doi:10.1071/CH08186 87   4 Cited 7 times in Scopus7 0
Proctor, Lavinia M., Arumugam, Thiruma V., Shiels, Ian, Reid, Robert C., Fairlie, David P. and Taylor, Stephen M . (2004) Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury. British Journal of Pharmacology, 142 4: 756-764. doi:10.1038/sj.bjp.0705819 83   43 Cited 50 times in Scopus50 0
Arumugam, Thiruma V., Arnold, Naomi, Proctor, Lavinia M., Newman, Michelle, Reid, Robert C., Hansford, Karl A., Fairlie, David P., Shiels, Ian A. and Taylor, Stephen M. (2003) Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British Journal of Pharmacology, 140 1: 71-80. doi:10.1038/sj.bjp.0705402 93   30 Cited 32 times in Scopus32 0
Crossley, M. J. and Reid, R. C. (1994) Concise Synthesis of Arogenate. A Biosynthetic Precursor of Phenylalanine and Tyrosine. Journal of the Chemical Society, Chemical Communications, 19: 2237-2238. doi:10.1039/c39940002237 50   6 0
Wong, A. K., Reid, R. C., Abbenante, J. and Fairlie, D. P. (1997) Conformationally constrained cyclic mimetics of protein and peptide surfaces.. Abstracts of Papers of The American Chemical Society, 214 388-ORGN. 53   0
Reid, RC, Kelso, MJ, Scanlon, MJ and Fairlie, DP (2002) Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents. Journal of The American Chemical Society, 124 20: 5673-5683. doi:10.1021/ja0256461 111   38 Cited 36 times in Scopus36 0
Fairlie, D. P., Tyndall, J. D. A., Reid, R. C., Wong, A. K., Abbenante, G., Scanlon, M. J., March, D. R., Bergman, D. A., Chai, C. L. L. and Burkett, B. A. (2000) Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing. Journal of Medicinal Chemistry, 43 7: 1271-1281. doi:10.1021/jm990315t 102   102 Cited 105 times in Scopus105 0
Reid, Robert C., Pattenden, Lenard K., Tyndall, Joel D. A., Martin, Jennifer L., Walsh, Terry and Fairlie, David P. (2004) Countering cooperative effects in protease inhibitors using constrained b-strand-mimicking templates in focused combinatorial libraries. Journal of Medicinal Chemistry, 47 7: 1641-1651. doi:10.1021/jm030337m 92   33 Cited 32 times in Scopus32 0
Tyndall, Joel D. A., Pattenden, Leonard K., Reid, Robert C., Hu, Shu-Hong, Alewood, Dianne, Alewood, Paul F., Walsh, Terry, Fairlie, David P. and Martin, Jennifer L. (2008) Crystal structures of highly constrained Substrate and Hydrolysis products bound to HIV-1 Protease. Implications for the Catalytic Mechanism. Biochemistry, 47 12: 3736-3744. doi:10.1021/bi7023157 67   11 Cited 7 times in Scopus7 0
Halili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010) Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 6: 1103-1114. doi:10.1189/jlb.0509363 116   52 Cited 55 times in Scopus55 0
Reid, Robert C., Yau, Mei-Kwan, Singh, Ranee, Hamidon, Johan K., Reed, Anthony N., Chu, Peifei, Suen, Jacky Y., Stoermer, Martin J., Blakeney, Jade S., Lim, Junxian, Faber, Jonathan M. and David P. Fairlie, (2013) Downsizing a human inflammatory protein to a small molecule with equal potency and functionality. Nature Communications, 4 2802: 1-9. doi:10.1038/ncomms3802 70   4 Cited 4 times in Scopus4 34
Hansford, Karl A., Reid, Robert C., Clark, Chris I., Tyndall, Joel D. A., Whitehouse, Michael W., Guthrie, Tom, McGeary, Ross P., Schafer, Karl, Martin, Jennifer L. and Fairlie, David P. (2003) D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A(2) (IIa) with antiinflammatory activity. Chembiochem, 4 2-3: 181-185. doi:10.1002/cbic.200390029 126   54 Cited 59 times in Scopus59 0
Ghassemian, Artin, Wang, Ching-I Anderson, Yau, Mei-Kwan, Reid, Robert C., Lewis, Richard J., Fairlie, David P., Alewood, Paul F. and Durek, Thomas (2013) Efficient chemical synthesis of human complement protein C3a. Chemical Communications, 49 23: 2356-2358. doi:10.1039/c3cc40537k 68 62 3 Cited 3 times in Scopus3 0
Shakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013) Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 35: 25362-25374. doi:10.1074/jbc.M113.496281 55   5 Cited 4 times in Scopus4 0
Strachan, Anna J., Shiels, Ian A., Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and R. A. North (2001) Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist. British Journal of Pharmacology, 134 12: 1778-1786. doi:10.1038/sj.bjp.0704417 74   43 0
Strachan, Anna J., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002) Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (vol 134, pg 1778, 2001). British Journal of Pharmacology, 135 2: 579-580. doi:10.1038/sj.bjp.0704531 56   0 0
Iyer, Abishek, Woodruff, Trent M., Wu, Mike C. L., Stylianou, Con, Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and Brown, Lindsay (2011) Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats. Journal of Cardiovascular Pharmacology, 58 5: 479-486. doi:10.1097/FJC.0b013e31822a7a09 37   11 Cited 11 times in Scopus11 1
Gregory, Laura S., Kelly, Wendy L., Reid, Robert C., Fairlie, David P. and Forwood, Mark R. (2006) Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats. Bone, 39 1: 134-142. doi:10.1016/j.bone.2005.12.017 378   24 Cited 25 times in Scopus25 0
Reid, Robert C. (2005) Inhibitors of Secretory Phospholipase A2 Group IIA. Current medicinal chemistry, 12 25: 3011-3026. doi:10.2174/092986705774462860 54   55 Cited 64 times in Scopus64 0
Gupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010) Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 23: 7067-7070. doi:10.1016/j.bmcl.2010.09.100 63   13 Cited 12 times in Scopus12 0
Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators. In: Abstracts of Papers of the American Chemical Society. , , (). . 11   0
Fairlie, D. P. and Reid, R. C. (1997). Mimicking extended conformations of protease substrates: Designing cyclic peptidomimetics to inhibit HIV-1 protease. In Advances in amino acid mimetics and peptidomimetics (pp. 77-107) London: JAI Press Inc. 37  
Martin, J. L., Begun, J., Schindeler, A., Wickramasinghe, W. A., Alewood, D., Alewood, P. F., Bergman, D. A., Brinkworth, R. I., Abbenante, G., March, D. R., Reid, R. C., Fairlie, D. P. and Armstrong, Richard A. (1999) Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38 25: 7978-7988. doi:10.1021/bi990174x 172   44 Cited 38 times in Scopus38 0
Clark, C. I., Fairlie, D. P., Hansford, K., McGeary, R. P., Reid, R. C. and Stoermer, M. J. (2007). New amino acid derivatives useful for the treatment of inflammatory disease or condition e.g. rheumatic arthritis. . 55  
Blakeney, J. S, Reid, R. C, Le, G. T and Fairlie, D. P (2007) Nonpeptidic ligands for peptide-activated G protein-coupled receptors. Chemical Reviews, 107 7: 2960-3041. doi:10.1021/cr050984g 90   57 Cited 55 times in Scopus55 0
Barry, Grant D., Suen, Jacky Y., Le, Giang T., Cotterell, Adam, Reid, Robert C. and Fairlie, David P. (2010) Novel agonists and antagonists for human protease activated receptor 2. Journal of Medicinal Chemistry, 53 20: 7428-7440. doi:10.1021/jm100984y 61   27 Cited 24 times in Scopus24 3
Yau, Annika M., Liu, Ligong, Reid, Robert C., Barry, Grant D., Suen, Jacky Y., Lohman, Rink-Jan, Le, Giang T., Cotterell, Adam and Fairlie, David P. (2011). Novel agonists and antagonists for protease activated receptor 2. In: Abstracts of Papers of the 242nd National Meeting of the American Chemical Society. National Meeting of the American Chemical Society (242nd, ACS, 2011), Denver, CO, U.S.A., (). 28 August-1 September 2011. 54   0
Reid, Robert, C. and Fairlie, David P. (2008). Parallel synthesis af anticancer, antiinflammatory and antiviral agents derived from L- and D- amino acids. In Tushar Kshirsagar (Ed.), High-throughput lead optimisation in drug discovery (pp. 177-194) Boca Raton, USA: CRC Press. 73  
Duprez, Wilko, Premkumar, Lakshmanane, Halili, Maria A., Lindahl, Fredrik, Reid, Robert C., Fairlie, David P. and Martin, Jennifer L. (2014) Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence. Journal of Medicinal Chemistry, 58 2: 577-587. doi:10.1021/jm500955s 12   Cited 0 times in Scopus0 4
Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., Melville, Lewis A., Beattie, Lynette, Gardiner, Donald L., Reid, Robert C., Stoermer, Martin J., Skinner-Adams, Tina, Berry, Colin and McCarthy, James S. (2006) Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrobial Agents And Chemotherapy, 50 2: 639-648. doi:10.1128/AAC.50.2.639-648.2006 104   78 Cited 82 times in Scopus82 4
March, Darren R., Proctor, Lavinia M., Stoermer, Martin J., Sbaglia, Robert, Abbenante, Giovanni, Reid, Robert C., Woodruff, Trent M., Wadi, Khemar, Paczkowski, Natalii, Tyndall, Joel D. A., Taylor, Stephen M. and Fairlie, David P. (2004) Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity. Molecular Pharmacology, 65 4: 868-879. doi:10.1124/mol.65.4.868 79   41 Cited 37 times in Scopus37 0
Reid, Robert C., Yau, Mei-Kwan, Singh, Ranee, Hamidon, Johan K., Lim, Junxian, Stoermer, Martin J. and Fairlie, David P. (2014) Potent heterocyclic ligands for human complement C3a receptor. Journal of Medicinal Chemistry, 57 20: 8459-8470. doi:10.1021/jm500956p 15   0 Cited 0 times in Scopus0 3
Arumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and M. Colombo (2004) Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 6: 934-941. doi:10.1016/j.jhep.2004.02.017 94   46 Cited 51 times in Scopus51 0
Arumugam, Thiruma V., Shiels, Ian A., Woodruff, Trent M., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002) Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine. Journal of Surgical Research, 103 2: 260-267. doi:10.1006/jsre.2002.6369 66   70 Cited 73 times in Scopus73 0
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2004) Protective effects of a potent C5a receptor antagonist on experimental acute limb ishemia-reperfusion in rats. Journal of Surgical Research, 116 1: 81-90. doi:10.1016/j.jss.2003.04.001 130   49 Cited 50 times in Scopus50 0
Scully, Conor C. G., Blakeney, Jade S., Singh, Ranee, Hoang, Huy N., Abbenante, Giovanni, Reid, Robert C. and Fairlie, David P. (2010) Selective hexapeptide agonists and antagonists for human complement C3a receptor. Journal of Medicinal Chemistry, 53 13: 4938-4948. doi:10.1021/jm1003705 81   11 Cited 12 times in Scopus12 0

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