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Bertalli, Nadine A., Allen, Katrina J., McLaren, Christine E., Turkovic, Lidija, Osborne, Nicholas J., Constantine, Clare C., Delatycki, Martin B., English, Dallas R., Giles, Graham G., Hopper, John L., Anderson, Gregory J., Olynyk, John K., Powell, Lawrie W., Gurrin, Lyle C. and for the HealthIron Study Investigators (2011) A comparison of self-reported and record-linked blood donation history in an Australian cohort. Transfusion, 51 10: 2189-2198. doi:10.1111/j.1537-2995.2011.03141.x 47   2 Cited 2 times in Scopus2 0
Phatak, P, Brissot, P, Wurster, M, Adams, PG, Bonkovsky, HL, Gross, J, Malfertheiner, P, McLaren, GD, Niederau, C, Piperno, A, Powell, LW, Russo, MW, Stoelzel, U, Stremmel, W, Griffel, L, Lynch, N, Zhang, YY and Pietrangelo, A (2010) A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis. Hepatology, 52 5: 1671-1679. doi:10.1002/hep.23879 139   25 Cited 27 times in Scopus27 0
Phatak, PD, Brissot, P, Bonkovsky, H, Wurster, M, Powell, L, Niederau, C, Adams, P, Stremmel, W, Griffel, L, Lynch, N, Schoenborn-Kellenberger, O and Pietrangelo, A (2009). A Phase I/II, Open-Label, Dose-Escalation Trial of Once-Daily Oral Chelator Deferasirox to Treat Iron Overload in HFE-Related Hereditary Hemochromatosis: Final Results of the Core Study.. In: BLOOD. 51st Annual Meeting of the American-Society-of-Hematology, New Orleans LA, (607-608). DEC 05-08, 2009. 132   0
Phatak, P., Brissot, P., Wurster, M., Adams, P. C., Bonkovsky, HL, Gross, J, Malfertheiner, P, McLaren, G. D., Niederau, C., Piperno, A., Powell, L. W., Russo, M., Stoelzel, U., Stremmel, W., Griffel, L., Lynch, N., Zhang, Y. and Pietrangelo, A. (2010). A phase I/II, open-label, dose-escalation trial using the once-daily oral chelator deferasirox to treat iron overload in HFE-related hereditary hemochromatosis: Final results. In: Abstracts of the International Liver Congress™ 2010 – the 45th annual meeting of the European Association for the Study of the Liver (EASL). 45th Annual Meeting of the European Association for the Study of Liver, Vienna, Austria, (S-81-S-81). 14-18 April 2010. doi:10.1016/S0168-8278(10)60189-4 81   1 0
Gochee, PA, Powell, LW, Cullen, DJ, Du Sart, D, Rossi, E and Olynyk, JK (2002) A population-based study of the biochemical and clinical expression of the H63D hemochromatosis mutation. Gastroenterology, 122 3: 646-651. doi:10.1053/gast.2002.31903 76   156 Cited 168 times in Scopus168 0
O'Neil, Jillian and Powell, Lawrie (2005) Clinical aspects of hemochromatosis. Seminars in Liver Disease, 25 4: 381-391. doi:10.1055/s-2005-923310 35   32 Cited 37 times in Scopus37 0
Wood, Marnie J., Powell, Lawrie W., Dixon, Jeannette L. and Ramm, Grant A. (2012) Clinical cofactors and hepatic fibrosis in hereditary hemochromatosis: the role of diabetes mellitus. Hepatology, 56 3: 904-911. doi:10.1002/hep.25720 40   7 Cited 9 times in Scopus9 1
Whiting, PW, Fletcher, LM, Dixon, JK, Gochee, P, Powell, LW and Crawford, DHG (2002) Concordance of iron indices in homozygote and heterozygote sibling pairs in hemochromatosis families: implications for family screening. Journal of Hepatology, 37 3: 309-314. doi:10.1016/S0168-8278(02)00216-7 120   17 Cited 19 times in Scopus19 0
Wood, M. J., Vigh, S., Dixon, J. L., Ramm, G. A. and Powell, L. W. (2010). Diabetes is associated with fibrosis progression in haemochromatosis. In: Australian Gastroenterology Week 2010, Gold Coast, Qld, Australia, (A110-A110). 20-23 October 2010. doi:10.1111/j.1440-1746.2010.06457.x 44   0 0
Bacon, Bruce R., Adams, Paul C., Kowdley, Kris V., Powell, Lawrie W. and Tavill, Anthony S. (2011) Diagnosis and management of hemochromatosis: 2011 Practice Guideline by the American Association for the Study of Liver Diseases. Hepatology, 54 1: 328-343. doi:10.1002/hep.24330 46   56 Cited 74 times in Scopus74 2
Bridle, K. R., Frazer, D. M., Wilkins, S. J., Dixon, J. L., Purdie, D. M., Crawford, D. H. G., Subramaniam, V. N, Powell, L. W., Anderson, G. J. and Ramm, G. A. (2003) Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet, 361 9358: 669-673. doi:10.1016/S0140-6736(03)12602-5 92   390 Cited 425 times in Scopus425 0
Wood, Marnie J, Gadd, Victoria L., Powell, Lawrie W., Ramm, Grant A. and Clouston, Andrew D. (2014) Ductular reaction in hereditary hemochromatosis: The link between hepatocyte senescence and fibrosis progression. Hepatology, 59 3: 848-857. doi:10.1002/hep.26706 23   4 Cited 6 times in Scopus6 1
Rossi, E, Bulsara, MK, Olynyk, JK, Cullen, DJ, Summerville, L and Powell, LW (2001) Effect of hemochromatosis genotype and lifestyle factors on iron and red cell indices in a community population. Clinical Chemistry, 47 2: 202-208. 40   59
Wood, M.J., Powell, L.W. and Ramm, G. A. (2008) Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis. Blood, 111 9: 4456-4462. doi:10.1182/blood-2007-11-122374 48   38 Cited 41 times in Scopus41 0
Bridle, K. R., Crawford, D. H. G., Fletcher, L. M., Smith, J. L., Powell, L. W. and Ramm, G. A. (2003) Evidence for a sub-morphological inflammatory process in the liver in haemochromatosis. Journal of Hepatology, 38 4: 426-433. doi:10.1016/S0168-8278(02)00444-0 77   23 Cited 26 times in Scopus26 0
Peverill, William, Powell, Lawrie W. and Skoien, Richard (2014) Evolving concepts in the pathogenesis of NASH: Beyond steatosis and inflammation. International Journal of Molecular Sciences, 15 5: 8591-8638. doi:10.3390/ijms15058591 17   2 Cited 3 times in Scopus3 0
Anderson, Gregory J. and Powell, Lawrie W. (1999) Haemochromatosis and control of intestinal iron absorption [Commentry]. Lancet, 353 9170: 2089-2090. doi:10.1016/S0140-6736(99)00113-0 43   4 Cited 5 times in Scopus5 0
Powell, Lawrie W., Subramaniam, V. Nathan and Yapp, Thomas R. (2000) Haemochromatosis in the new millennium. Journal of Hepatology, 32 Supplement 1: 48-62. doi:10.1016/S0168-8278(00)80415-8 56   76 Cited 84 times in Scopus84 0
Allen, K. J., Gurrin, L. C., Osborne, N. J., Constantine, C. C., Delatycki, M. B., Nicoll, A. J., McLaren, C. E., Bahlo, M., Fletcher, A. S., Nisselle, A. E., Forrest, S., Vulpe, C. D., Anderson, G. J., Giles, G. G., English, D. R., Hopper, J. L., Olynyk, J. K., Powell, L. W. and Gertig, D. M. (2007). Healthiron: a longitudinal population study defining the burden of disease in HFE-associated hereditary hemochromatosis. In: International BioIron Society Abstracts. 2007 International BioIron Society Meeting, Kyoto, Japan, (537-537). 1-6 April 2007. doi:10.1002/ajh.20964 38   0 0
Powell, Laurie W. and Yapp, Thomas R. (2000) Hemochromatosis. Clinics in Liver Disease, 4 1: 211-228. 79  
Fletcher, Linda M. and Powell, Lawrie W. (2003) Hemochromatosis and alcoholic liver disease. Alcohol, 30 2: 131-136. doi:10.1016/S0741-8329(03)00128-9 124   36 Cited 41 times in Scopus41 1
Gurrin, Lyle C., Bertalli, Nadine A., Dalton, Gregory W., Osborne, Nicholas J., Constantine, Clare C., McLaren, Christine E., English, Dallas R., Gertig, Dorota M., Delatycki, Martin B., Nicoll, Amanda J., Southey, Melissa C., Hopper, John L., Giles, Graham G., Anderson, Gregory J., Olunyk, John K., Powell, Lawrie W. and Allen, Katrina J. (2009) HFE C282Y/H63D compound heterozygotes are at low risk of hemochromatosis-related morbidity. Hepatology, 50 1: 94-101. doi:10.1002/hep.22972 40   35 Cited 38 times in Scopus38 1
Osborne, NJ, Gurrin, LC, Allen, KJ, Constantine, CC, Delatycki, MB, McLaren, CE, Gertig, DM, Anderson, GJ, Southey, MC, Olynyk, JK, Powell, LW, Hopper, JL, Giles, GG and English, DR (2010) HFE C282Y homozygotes are at increased risk of breast and colorectal cancer. Hepatology, 51 4: 1311-1318. doi:10.1002/hep.23448 81   42 Cited 49 times in Scopus49 1
Allen, Katrina J., Bertalli, Nadine A., Osborne, Nicholas J., Constantine, Clare C., Delatycki, Martin B., Nisselle, Amy E., Nicoll, Amanda J., Gertig, Dorota M., McLaren, Christine E., Giles, Graham G., Hopper, John L., Anderson, Gregory J., Olynyk, John K., Powell, Lawrie W., Gurrin, Lyle C. and HealthIron Study Investigators (2010) HFE Cys282Tyr Homozygotes With Serum Ferritin Concentrations Below 1000 mu g/L Are at Low Risk of Hemochromatosis. Hepatology, 52 3: 925-933. doi:10.1002/hep.23786 116   16 Cited 15 times in Scopus15 0
Osborne, N. J., Gurrin, L. C., Allen, K. J., Constantine, C. C., Delatycki, M. B., Nisselle, A. E., Fletcher, A. R., McLaren, C. E., English, D. R., Hopper, J. L., Giles, G. G., Olynyk, J., Nicoll, A., Powell, L. W. and Gertig, D. M. (2007). Homozygosity for the C282Y mutation in the HFE gene is associated with increased risk of colorectailand breast cancer in Australian population. In: International BioIron Society Abstracts. 2007 International BioIron Society Meeting, Kyoto, Japan, (575-575). 1-6 April 2007. doi:10.1002/ajh.20964 21   2 0
Powell, Elizabeth E., Pender, Michael P., Chalk, Jonathan B., Parkin, Philip J., Strong, Russell, Lynch, Stephen, Kerlin, Paul, Cooksley, W. Graham, Cheng, Wendy and Powell, Lawrie W. (1990) Improvement in Chronic Hepatocerebral Degeneration Following Liver Transplantation. Gastroenterology, 98 4: 1079-1082. 371 784 38
Stuart, KA, Anderson, GJ, Frazer, DM, Murphy, TL, Powell, LW, Fletcher, LM and Crawford, DH (2004) Increased duodenal expression of divalent metal transporter 1 and iron-regulated gene 1 in cirrhosis. Hepatology, 39 2: 492-499. doi:10.1002/hep.20038 72   13 Cited 14 times in Scopus14 0
Gurrin, L. C., Allen, K. J., Osborne, N. J., Constantine, C. C., Delatycki, M. B., Nisselle, A. E., Fletcher, A. R., McLaren, C. E., Anderson, G. J., English, D. R., Hopper, J. L., Giles, G. G., Olynyk, J., Nicoll, A., Powell, L. W. and Gertig, D. M. (2007). Iron measures at baseline and follow-up from a longitudinal study of modifiers of hereditary haemochromatosis: the healthiron study. In: International BioIron Society Abstracts. 2007 International BioIron Society Meeting, Kyoto, Japan, (537-537). 1-6 April 2007. doi:10.1002/ajh.20964 21   0 0
Allen, Katrina J., Gurrin, Lyle C., Constantine, Clare C., Osborne, Nicholas J., Delatycki, Martin B., Nicoll, Amanda J., McLaren, Christine E., Bahlo, Melanie, Nisselle, Amy E., Vulpe, Chris D., Anderson, Gregory J., Southey, Melissa C., Giles, Graham G., English, Dallas R., Hopper, John L., Olynyk, John K., Powell, Lawrie W. and Gertig, Dorota M. (2008) Iron-overload-related disease in HFE hereditary hemochromatosis. New England Journal of Medicine, 358 3: 221-230. doi:10.1056/NEJMoa073286 29   247 Cited 283 times in Scopus283 31
Macdonald, G., Bridle, K. R., Ward, P. J., Walker, N. I., Houglum, K., George, D. K., Smith, J. L., Powell, L. W., Crawford, D. and Ramm, G. A. (2001) Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3. Journal of Gastroenterology and Hepatology, 16 6: 599-606. doi:10.1046/j.1440-1746.2001.02445.x 228   74 Cited 86 times in Scopus86 0
Powell, L. W., Bassett, M. and Cooksley, W. G. E. (2006). Liver Function Tests in Abnormal Laboratory Results. In Geoffrey Kellerman (Ed.), Abnormal Laboratory Results 2nd ed. (pp. 88-94) North Ryde, N.S.W.: McGraw-Hill. 191  
Gan, Eng K., Powell, Lawrie W. and Olynyk, John K. (2011) Natural history and management of HFE-hemochromatosis. Seminars in Liver Disease, 31 3: 293-301. doi:10.1055/s-0031-1286060 64 1 11 Cited 13 times in Scopus13 1
O'Brien, Julia and Powell, Lawrie W. (2012) Non-alcoholic fatty liver disease: Is iron relevant?. Hepatology International, 6 1: 332-341. doi:10.1007/s12072-011-9304-9 61 2 4 Cited 7 times in Scopus7 0
Powell, Lawrie W. (2009) Overview: liver disease and transplantation. Journal of gastroenterology and hepatology, 24 Suppl. s3: S97-S104. doi:10.1111/j.1440-1746.2009.06079.x 11   1 Cited 2 times in Scopus2 0
Crawford, DHG, Fletcher, LM, Hubscher, SG, Stuart, KA, Gane, E, Angus, PW, Jeffrey, GP, McCaughan, GW, Kerlin, P, Powell, LW and Elias, EE (2004) Patient and graft survival after liver transplantation for hereditary hemochromatosis: Implications for pathogenesis. Hepatology, 39 6: 1655-1662. doi:10.1002/hep.20242 94   40 Cited 52 times in Scopus52 0
McCullen, M. A., Fletcher, L. M., Dimeski, G., Pink, A., Powell, L. W., Crawford, D.H. and Hickman, P. E. (2008) Patient-focused outcomes following detection in a hospital-based screening programme for C282Y haemochromatosis. Internal Medicine Journal, 38 8: 651-656. doi:10.1111/j.1445-5994.2007.01578.x 50   0 Cited 0 times in Scopus0 0
Yapp, T. R., Eijkelkamp, E. J. and Powell, L. W. (2001) Population screening for HFE-associated haemochromatosis: should we have to pay for our genes?. Internal Medicine Journal, 31 1: 48-52. doi:10.1046/j.1445-5994.2001.00005.x 36   8 Cited 5 times in Scopus5 0
Herath, N. I., Kew, M. C., Walsh, M. D., Young, J., Powell, L. W., Leggett, B. A. and Macdonald, G.A. (2002) Reciprocal relationship between methylation status and loss of heterozygosity at the p14 (ARF) locus in Australian and South African hepatocellular carcinomas. Journal of Gastroenterology And Hepatology, 17 3: 301-307. doi:10.1046/j.1440-1746.2002.02704.x 151   15 Cited 14 times in Scopus14 0
Powell, Lawrie W., Dixon, Jeannette L. and Hewett, David G. (2005) Role of early case detection by screening relatives of patients with HFE-associated hereditary haemochromatosis. Best Practice and Research Clinical Haematology, 18 2: 221-234. doi:10.1016/j.beha.2004.10.001 34   8 Cited 8 times in Scopus8 0
Bridle, Kim R., Crawford, Darrell H. G., Powell, Lawrie W. and Ramm, Grant A. (2001) Role of myofibroblasts in tumour encapsulation of hepatocellular carcinoma in haemochromatosis. Liver, 21 2: 96-104. doi:10.1034/j.1600-0676.2001.021002096.x 82   15 Cited 15 times in Scopus15 0
Powell, Lawrie W., Dixon, Jeannette L., Ramm, Grant A., Purdie, David M., Lincoln, Douglas J., Anderson, Gregory J., Subramaniam, V. Nathan, Hewett, David G., Searle, Jeffrey W., Fletcher, Linda M., Crawford, Darrell H., Rodgers, Helen, Allen, Katrina J., Cavanaugh, Juleen A. and Bassett, Mark L. (2006) Screening for hemochromatosis in asymptomatic subjects with or without a family history. Archives of Internal Medicine, 166 3: 294-301. doi:10.1001/archinte.166.3.294 109   84 Cited 95 times in Scopus95 0
Crawford, D. H. G., Murphy, T. L., Ramm, L. E., Fletcher, L. M., Clouston, AD, Anderson, G. J., Subramaniam, V. N., Powell, L. W. and Ramm, G. A. (2009) Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. Hepatology, 49 2: 418-425. doi:10.1002/hep.22650 44   22 Cited 29 times in Scopus29 0
Crawford, Darrell H., Murphy, Therese L., Ramm, Louise E., Fletcher, Linda M., Clouston, Andrew D., Anderson, Gregory J., Subramaniam, V. Nathan, Powell, Lawrie W. and Ramm, Grant A. (2008). Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. In: The 59th Annual Meeting of the American Association for the Study of Liver Diseases. The Liver Meeting 2008: 59th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, U.S.A., (437A-437A). 31 October-4 November 2008. doi:10.1002/hep.22641 67   0 0
Crawford, D. H. G., Murphy, T. L., Ramm, L. E., Fletcher, L. M., Clouston, A. D., Anderson, G. J., Subramaniam, V. N., Powell, L. W. and Ramm, G. A. (2008). Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. In: Special Issue: Australian Gastroenterology Week. AGW 2008: Australian Gastroenterology Week 08, Brisbane, QLD, Australia, (A244-A244). 22-25 October 2008. doi:10.1111/j.1440-1746.2008.05613.x 49   0 0
Pascoe, A., Kerlin, P., Steadman, C., Clouston, A. D., Jones, D., Powell, L. W., Jazwinska, E. C., Lynch, S. V. and Strong, R. W. (1999) Spur cell anaemia and hepatic iron stores in patients with alcoholic liver disease undergoing orthotopic liver transplantation. Gut, 45 2: 301-305. 64   27
Powell, Elizabeth E., Ali, Azmat, Clouston, Andrew D., Dixon, Jeannette L., Lincoln, Douglas J., Purdie, David M., Fletcher, Linda M., Powell, Lawrie W. and Jonsson, Julie R. (2005) Steatosis is a cofactor in liver injury in hemochromatosis. Gastroenterology, 129 6: 1937-1943. doi:10.1053/j.gastro.2005.09.015 103   70 Cited 81 times in Scopus81 0
Walsh, Alissa, Dixon, Jeannette L., Ramm, Grant A., Hewett, David G., Lincoln, Douglas J., Anderson, Gregory J., Subramaniam, V. Nathan, Dodemaide, Julian, Cavanaugh, Juleen A., Bassett, Mark L. and Powell, Lawrie W. (2006) The clinical relevance of compound heterozygosity for the C282Y and H63D substitutions in hemochromatosis. Clinical Gastroenterology and Hepatology, 4 11: 1403-1410. doi:10.1016/j.cgh.2006.07.009 93   39 Cited 43 times in Scopus43 0
Clark, Paul, Britton, Laurence J. and Powell, Lawrie W. (2010) The diagnosis and management of hereditary haemochromatosis. Clinical Biochemist Reviews, 31 1: 3-8. 19  
Gurrin, Lyle C., Osborne, Nicholas J., Constantine, Clare C., McLaren, Christine E., English, Dallas R., Gertig, Dorota M., Delatycki, Martin B., Southey, Melissa C., Hopper, John L., Giles, Graham G., Anderson, Gregory J., Olynyk, John K., Powell, Laurie W. and Allen, Katrina J. (2008) The natural history of serum iron indices for HFE C282Y homozygosity associated with hereditary hemochromatosis. Gastroenterology, 135 6: 1945-1952. doi:10.1053/j.gastro.2008.08.056 32   37 Cited 46 times in Scopus46 0
Wood, MJ, Powell, LW, Ramm, GA and Clouston, AD (2010). The role of the ductular reaction in the progression of hepatic fibrosis in haemochromatosis. In: Australian Gastroenterology Week 2010. Australian Gastroenterology Week 2010, Gold Coast , QLD, Australia, (A110-A111). 20-23 October 2010. doi:10.1111/j.1440-1746.2010.06457.x 34   0 0

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