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Totsika, Makrina, Kostakioti, Maria, Hannan, Thomas J., Upton, Mathew, Beatson, Scott A., Janetka, James W., Hultgren, Scott J. and Schembri, Mark A. (2013) A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug resistant uropathogenic Escherichia coli ST131. Journal of Infectious Diseases, 208 6: 921-928. doi:10.1093/infdis/jit245 50   15 Cited 16 times in Scopus16 0
Adams, Luke A., Sharma, Pooja, Mohanty, Biswaranjan, Ilyichova, Olga V., Mulcair, Mark D., Williams, Martin L., Gleeson, Ellen C., Totsika, Makrina, Doak, Bradley C., Caria, Sofia, Rimmer, Kieran, Horne, James, Shouldice, Stephen R., Vazirani, Mansha, Headey, Stephen J., Vazirani, Mansha, Headey, Stephen J., Plumb, Brent R., Martin, Jennifer L., Heras, Begona, Simpson, Jamie S. and Scanlon, Martin J. (2014) Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA1. Angewandte Chemie, . doi:10.1002/ange.201410341 17   0
Wells, Timothy J., Totsika, Makrina and Schembri, Mark A. (2010) Autotransporters of Escherichia coli: A sequence-based characterization. Microbiology, 156 8: 2459-2469. doi:10.1099/mic.0.039024-0 76   26 Cited 24 times in Scopus24 0
Wurpel, Daniel J., Beatson, Scott A., Totsika, Makrina, Petty, Nicola K. and Schembri, Mark A. (2013) Chaperone-usher fimbriae of Escherichia coli. PLoS One, 85 1: e52835.1-e52835.11. doi:10.1371/journal.pone.0052835 63   14 Cited 11 times in Scopus11 0
King, Nathan P, Sakinc, Turkan, Ben Zakour, Nouri L, Totsika, Makrina, Heras, Begona, Simerska, Pavla, Shepherd, Mark, Gatermann, Soren G, Beatson, Scott A and Schembri, Mark A (2012) Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance. BMC Microbiology, 12 1: 8.1-8.25. doi:10.1186/1471-2180-12-8 41   2 Cited 2 times in Scopus2 1
Easton, Donna M., Totsika, Makrina, Allsopp, Luke P., Phan, Minh-Duy, Idris, Adi, Wurpel, Daniël J., Sherlock, Orla, Zhang, Bing, Venturini, Carola, Beatson, Scott A., Mahony, Timothy J., Cobbold, Rowland N. and Schembri, Mark A. (2011) Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli. Frontiers in Microbiology: Frontiers in Cellular and Infection Microbiology, 2 JUNE: 120.1-120.9. doi:10.3389/fmicb.2011.00120 193   10 Cited 9 times in Scopus9 1
Totsika, Makrina, Heras, Begona, Wurpel, Daniel J. and Schembri, Mark A. (2009) Characterization of two homologous disulfide bond systems involved in virulence factor biogenesis in uropathogenic Escherichia coli CFT073. Journal of Bacteriology, 191 12: 3901-3908. doi:10.1128/JB.00143-09 46   24 Cited 23 times in Scopus23 0
Holden, N. J., Blomfield, I., Uhlin, B. E., Totsika, M., Kulasekara, D. H. and Gally, D. L. (2007) Comparative analysis of FimB and FimE recombinase activity. Microbiology, 153 4138-4149. doi:10.1099/mic.0.2007/010363-0 38   11 Cited 11 times in Scopus11 0
Wurpel, Daniel J., Moriel, Danilo G., Totsika, Makrina, Easton, Donna M. and Schembri, Mark A. (2015) Comparative analysis of the uropathogenic Escherichia coli surface proteome by tandem mass-spectrometry of artificially induced outer membrane vesicles. Journal of Proteomics, 115 93-106. doi:10.1016/j.jprot.2014.12.005 19   0 Cited 0 times in Scopus0 3
Watts, Rebecca E., Totsika, Makrina, Challinor, Victoria L., Mabbett, Amanda N., Ulett, Glen C., De Voss, James J. and Schembri, Mark A. (2012) Contribution of siderophore systems to growth and urinary tract colonization of asymptomatic bacteriuria Escherichia coli. Infection and Immunity, 80 1-2: 333-344. doi:10.1128/IAI.05594-11 46   18 Cited 19 times in Scopus19 0
Holden, Nicola J., Totsika, Makrina, Mahler, Eva, Roe, Andrew J., Catherwood, Kirsteen, Lindner, Karin, Dobrindt, Ulrich and Gally, David L. (2006) Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli. Microbiology, 152 4: 1143-1153. doi:10.1099/mic.0.28677-0 98   42 Cited 37 times in Scopus37 0
Selkrig, Joel, Mosbahi, Khedidja, Webb, Chaille T., Belousoff, Matthew J., Perry, Andrew J., Wells, Timothy J., Morris, Faye, Leyton, Denisse L., Totsika, Makrina, Phan, Minh-Duy, Celik, Nermin, Kelly, Michelle, Oates, Clare, Hartland, Elizabeth L., Robins-Browne, Roy M., Ramarathinam, Sri Harsha, Purcell, Anthony W., Schembri, Mark A., Strugnell, Richard A., Henderson, Ian R., Walker, Daniel and Lithgow, Trevor (2012) Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural and Molecular Biology, 19 5: 506-510. doi:10.1038/nsmb.2261 103   39 Cited 38 times in Scopus38 9
Heras, B, Shouldice, S. R., Totsika, M, Scanlon, M. J., Schembri, M. A. and Martin, J. L. (2009) DSB proteins and bacterial pathogenicity. Nature Reviews Microbiology, 7 3: 215-225. doi:10.1038/nrmicro2087 70 4 104 Cited 96 times in Scopus96 3
Watts, Rebecca E., Tan, Chee K., Ulett, Glen C., Carey Alison J., Totsika, Makrina, Idris, Adi, Paton, Adrienne W., Morona, Renato, Paton, James C. and Schembri, Mark A. (2012) Escherichia coli 83972 expressing a P fimbriae oligosaccharide receptor mimic impairs adhesion of uropathogenic E. coli. Journal of Infectious Diseases, 206 8: 1242-1249. doi:10.1093/infdis/jis493 117   6 Cited 7 times in Scopus7 0
Watts, Rebecca E., Hancock, Viktoria, Ong, Cheryl-Lynn Y., Vejborg, Rebecca Munk, Mabbett, Amanda N., Totsika, Makrina, Looke, David F., Nimmo, Graeme R., Klemm, Per and Schembri, Mark A. (2010) Escherichia coli isolates causing asymptomatic bacteriuria in catheterized and noncatheterized individuals possess similar virulence properties. Journal of Clinical Microbiology, 48 7: 2449-2458. doi:10.1128/JCM.01611-09 70   10 Cited 14 times in Scopus14 0
Thompson, Mary F., Totsika, Makrina, Schembri, Mark A., Mills, Paul C., Seton, Erica J. and Trott, Darren J. (2011) Experimental colonization of the canine urinary tract with the asymptomatic bacteriuria Escherichia coli strain 83972. Veterinary Microbiology, 147 1-2: 205-208. doi:10.1016/j.vetmic.2010.06.007 65   7 Cited 7 times in Scopus7 0
Jarrott, R., Shouldice, S.R., Guncar, G., Totsika, M., Schembri, M.A. and Heras, B. (2010) Expression and crystallization of SeDsbA, SeDsbL and SeSrgA from Salmonella enterica serovar Typhimurium. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66 Part 5: 601-604. doi:10.1107/S1744309110011942 45   3 Cited 3 times in Scopus3 0
Wurpel, Daniël J., Totsika, Makrina, Allsopp, Luke P., Hartley-Tassell, Lauren E., Day, Christopher J., Peters, Kate M., Sarkar, Sohinee, Ulett, Glen C., Yang, Ji, Tiralongo, Joe, Strugnell, Richard A., Jennings, Michael P. and Schembri, Mark A. (2014) F9 fimbriae of uropathogenic Escherichia coli are expressed at low temperature and recognise Galβ1-3GlcNAc-containing glycans. PLoS One, 9 3: . doi:doi:10.1371/journal.pone.0093177 32   0
Allsopp, Luke P., Beloin, Christophe, Gomes Moriel, Danilo, Totsika, Makrina, Ghigo, Jean-Marc and Schembri, Mark A. (2012) Functional heterogeneity of the UpaH autotransporter protein from uropathogenic Escherichia coli. Journal of Bacteriology, 194 21: 5769-5782. doi:10.1128/JB.01264-12 54   5 Cited 6 times in Scopus6 0
Petty, Nicola K., Ben Zakour, Nouri L., Stanton-Cook, Mitchell, Skippington, Elizabeth, Totsika, Makrina, Forde, Brian M., Phan, Minh-Duy, Gomes Moriel, Danilo, Peters, Kate M., Davies, Mark, Rogers, Benjamin A., Dougan, Gordon, Rodriguez-Baño, Jesús, Pascual, Alvaro, Pitout, Johann D., Upton, Mathew, Paterson, David L., Walsh, Timothy R., Schembri, Mark A. and Beatson, Scott A. (2014) Global dissemination of a multidrug resistant Escherichia coli clone. Proceedings of the National Academy of Sciences, 111 15: 5694-5699. doi:10.1073/pnas.1322678111 82 1 15 43
Hannan, Thomas J., Totsika, Makrina, Mansfield, Kylie J., Moore, Kate H., Schembri, Mark A. and Hultgren, Scott J. (2012) Host-pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection. FEMS Microbiology Reviews, 36 3: 616-648. doi:10.1111/j.1574-6976.2012.00339.x 37   46 Cited 52 times in Scopus52 1
Vejborg, Rebecca M., de Evgrafov, Mari R., Phan, Minh Duy, Totsika, Makrina, Schembri, Mark A. and Hancock, Viktoria (2012) Identification of genes important for growth of asymptomatic Bacteriuria Escherichia coli in urine. Infection and Immunity, 80 9: 3179-3188. doi:10.1128/IAI.00473-12 50   4 Cited 6 times in Scopus6 0
Duell, Benjamin L., Carey, Alison J., Tan, Chee K., Cui, Xiangqin, Webb, Richard I., Totsika, Makrina, Schembri, Mark A., Derrington, Petra, Irving-Rodgers, Helen, Brooks, Andrew J., Cripps, Allan W., Crowley, Michael and Ulett, Glen C. (2012) Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense against bacterial urinary tract infection. Journal of Immunology, 188 2: 781-792. doi:10.4049/jimmunol.1101231 60   20 Cited 26 times in Scopus26 0
Totsika, Makrina, Beatson, Scott A., Sarkar, Sohinee, Phan, Minh-Duy, Petty, Nicola K., Bachmann, Nathan, Szubert, Marek, Sidjabat, Hanna E., Paterson, David L., Upton, Mathew and Schembri, Mark A. (2011) Insights into a multidrug resistant escherichia coli pathogen of the globally disseminated ST131 lineage: Genome analysis and virulence mechanisms. Plos One, 6 10: e26578-1-e26578-11. doi:10.1371/journal.pone.0026578 116   38 Cited 37 times in Scopus37 1
Bokil, Nilesh J., Totsika, Makrina, Carey, Alison J., Stacey, Katryn J., Hancock, Viktoria, Saunders, Bernadette M., Ravasi, Timothy, Ulett, Glenn C., Schembri, Mark A. and Sweet, Matthew J. (2011) Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages. Immunobiology, 216 11: 1164-1171. doi:10.1016/j.imbio.2011.05.011 53   13 Cited 12 times in Scopus12 0
Goh, H. M. Sharon, Beatson, Scott A., Totsika, Makrina, Moriel, Danilo G., Phan, Minh-Duy, Szubert, Jan, Runnegar, Naomi, Sidjabat, Hanna E., Paterson, David L., Nimmo, Graeme R., Lipman, Jeffrey and Schembri, Mark A. (2013) Molecular analysis of the Acinetobacter baumannii biofilm-associated protein. Applied and Environmental Microbiology, 79 21: 6535-6543. doi:10.1128/AEM.01402-13 115   4 Cited 5 times in Scopus5 4
Ong, Cheryl-lynn Y., Beatson, Scott A., Totsika, Makrina, Forestier, Christiane, McEwan, Alastair G. and Schembri, Mark A. (2010) Molecular analysis of type 3 fimbrial genes from Escherichia coli, Klebsiella and Citrobacter species. BMC Microbiology, 10 183: 1-12. doi:10.1186/1471-2180-10-183 40   13 Cited 12 times in Scopus12 3
Nethercott, Cara, Mabbett, Amanda N., Totsika, Makrina, Peters, Paul, Ortiz, Juan C., Nimmo, Graeme R., Coombs, Geoffrey W., Walker, Mark J. and Schembri, Mark A. (2013) Molecular characterization of endocarditis-associated Staphylococcus aureus. Journal of Clinical Microbiology, 51 7: 2131-2138. doi:10.1128/JCM.00651-13 78   3 Cited 2 times in Scopus2 1
Abraham, Sam, Chapman, Toni A., Zhang, Ren, Chin, James, Mabbett, Amanda N., Totsika, Makrina and Schembri Mark A. (2011) Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections. Journal of Clinical Microbiology, 50 3: 1027-1030. doi:10.1128/JCM.06671-11 47   4 Cited 5 times in Scopus5 0
Totsika, Makrina, Wells, Timothy J., Beloin, Christophe, Valle, Jaione, Allsopp, Luke P., King, Nathan P., Ghigo, Jean-Marc and Schembri, Mark A. (2012) Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli. Applied and Environmental Microbiology, 78 7: 2179-2189. doi:10.1128/AEM.06680-11 62   18 Cited 18 times in Scopus18 0
Allsopp, Luke P., Beloin, Christophe, Ulett, Glen C., Valle, Jaione, Totsika, Makrina, Sherlock, Orla, Ghigo, Jean-Marc and Schembri, Mark A. (2012) Molecular characterization of UpaB and UpaC, two new autotransporter proteins of uropathogenic Escherichia coli CFT073. Infection and Immunity, 80 1: 321-332. doi:10.1128/IAI.05322-11 50   19 Cited 19 times in Scopus19 0
Pope, Phillip B., Totsika, Makrina, de Carcer, Daniel Aguirre, Schembri, Mark A. and Morrison, Mark (2011) Muramidases found in the foregut microbiome of the Tammar wallaby can direct cell aggregation and biofilm formation. ISME Journal, 5 2: 341-350. doi:10.1038/ismej.2010.116 50   3 Cited 2 times in Scopus2 0
March, J. B., Jepson, C. D., Clark, J. R., Totsika, M. and Calcutt M. J. (2006) Phage library screening for the rapid identification and in vivo testing of candidate genes for a DNA vaccine against Mycoplasma mycoides subsp. mycoides Small Colony Biotype. Infection and Immunity, 74 1: 167-174. doi:10.1128/IAI.74.1.167-174.2006 40   18 Cited 18 times in Scopus18 0
Holden, Nicola, Totsika, Makrina, Dixon, Lynn, Catherwood, Kirsteen and Gally, David L. (2007) Regulation of P-fimbrial phase variation frequencies in Escherichia coli CFT073. Infection and Immunity, 75 7: 3325-3334. doi:10.1128/IAI.01989-06 45   21 Cited 19 times in Scopus19 0
Totsika, M., Beatson, S.A., Holden, N. and Gally, D.L. (2008) Regulatory interplay between pap operons in uropathogenic Escherichia coli. Molecular Microbiology, 67 5: 996-1011. doi:10.1111/j.1365-2958.2007.06098.x 35   15 Cited 14 times in Scopus14 0
Sarkar, Sohinee, Ulett, Glen C., Totsika, Makrina, Phan, Minh-Duy and Schembri, Mark A. (2014) Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli. PLoS One, 9 4: . doi:10.1371/journal.pone.0094786 37   3 Cited 4 times in Scopus4 0
Heras, B, Totsika, M, Jarrott, R, Shouldice, SR, Guncar, G, Achard, MES, Wells, TJ, Argente, MP, McEwan, AG and Schembri, MA (2010) Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium. Journal of Biological Chemistry, 285 24: 18423-18432. doi:10.1074/jbc.M110.101360 62   16 Cited 16 times in Scopus16 0
Shouldice, Stephen R., Heras, Begona, Walden, Patricia M., Totsika, Makrina, Schembri, Mark A. and Martin, Jennifer L. (2011) Structure and function of DsbA, a key bacterial oxidative folding catalyst. Antioxidants and Redox Signaling, 14 9: 1729-1760. doi:10.1089/ars.2010.3344 64   28 Cited 28 times in Scopus28 0
Heras, Begona, Totsika, Makrina, Peters, Kate M., Paxman, Jason J., Gee, Christine L., Jarrott, Russell J., Perugini, Matthew A., Whitten, Andrew E. and Schembri, Mark A. (2014) The antigen 43 structure reveals a molecular Velcrolike mechanism of autotransporter-mediated bacterial clumping. Proceedings of the National Academy of Sciences of the United States of America, 111 1: 457-462. doi:10.1073/pnas.1311592111 28   4 Cited 5 times in Scopus5 4
Forde, Brian M., Ben Zakour, Nouri L., Stanton-Cook, Mitchell, Phan, Minh-Duy, Totsika, Makrina, Peters, Kate M., Chan, Kok Gan, Schembri, Mark A., Upton, Mathew and Beatson, Scott A. (2014) The complete genome sequence of Escherichia coli EC958: a high quality reference sequence for the globally disseminated multidrug resistant E. coli O25b:H4-ST131 clone. PLoS One, 9 8: e104400.1-e104400.13. doi:10.1371/journal.pone.0104400 40   1 4
Mavromatis, Charalampos (Harris), Bokil, Nilesh J., Totsika, Makrina, Kakkanat, Asha, Schaale, Kolja, Cannistraci, Carlo V., Ryu, Taewoo, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A., Sweet, Matthew J. and Ravasi, Timothy (2015) The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host–pathogen interactions. Cellular Microbiology, . doi:10.1111/cmi.12397 20   Cited 0 times in Scopus0 3
Wells, Timothy J., McNeilly, Tom N., Totsika, Makrina, Mahajan, Arvind, Gally, David L. and Schembri, Mark A. (2009) The Escherichia coli O157:H7 EhaB autotransporter protein binds to laminin and collagen I and induces a serum IgA response in O157:H7 challenged cattle. Environmental Microbiology, 11 7: 1803-1814. doi:10.1111/j.1462-2920.2009.01905.x 53   17 Cited 16 times in Scopus16 0
Phan, Minh-Duy, Peters, Kate M., Sarkar, Sohinee, Lukowski, Samuel W., Allsopp, Luke P., Moriel, Danilo Gomes, Achard, Maud E. S., Totsika, Makrina, Marshall, Vikki M., Upton, Mathew, Beatson, Scott A. and Schembri, Mark A. (2013) The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone. PloS Genetics, 9 10: e1003834.1-e1003834.18. doi:10.1371/journal.pgen.1003834 63   11 Cited 11 times in Scopus11 9
King, Nathan P., Beatson, Scott A., Totsika, Makrina, Ulett, Glen C., Alm, Richard A., Manning, Paul A. and Schembri, Mark A. (2011) UafB is a serine-rich repeat adhesin of Staphylococcus saprophyticus that mediates binding to fibronectin, fibrinogen and human uroepithelial cells. Microbiology, 157 4: 1161-1175. doi:10.1099/mic.0.047639-0 112   11 Cited 11 times in Scopus11 0
Valle, Jaione, Mabbett, Amanda N., Ulett, Glen C., Toledo-Arana, Alejandro, Wecker, Karine, Totsika. Makrina, Schembri, Mark A., Ghigo, Jean-Marc and Beloin, Christophe (2008) UpaG, a new member of the trimeric autotransporter family of adhesins in uropathogenic Escherichia coli. Journal of Bacteriology, 190 12: 4147-4161. doi:10.1128/JB.00122-08 60   60 Cited 61 times in Scopus61 3
Allsopp, Luke P., Totsika, Makrina, Tree, Jai J., Ulett, Glen C., Mabbett, Amanda N., Wells, Timothy J., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2010) UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073. Infection and Immunity, 78 4: 1659-1669. doi:10.1128/IAI.01010-09 57   35 Cited 37 times in Scopus37 0
Totsika, Makrina, Moriel, Danilo Gomes, Idris, Adi, Rogers, Benjamin A., Wurpel, Daniel J., Phan, Minh-Duy, Paterson, David L. and Schembri, Mark A. (2012) Uropathogenic Escherichia coli mediated urinary tract infection. Current Drug Targets, 13 11: 1386-1399. doi:10.2174/138945012803530206 170 1 11 Cited 14 times in Scopus14 0
Ulett, G. C., Makrina Totsika, Kolja Schaale, Carey, A. J., Sweet, Matthew J. and Schembri, Mark A. (2013) Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection. Current Opinion in Microbiology, 16 1: 100-107. doi:10.1016/j.mib.2013.01.005 41 88 21 Cited 25 times in Scopus25 1
Mabbett, Amanda N., Ulett, Glen C., Watts, Rebecca E., Tree, Jai J., Totsika, Makrina, Ong, Cheryl-Lynn, Wood, Jacqueline M., Monaghan, Wayne, Looke, David F., Nimmo, Graeme R., Svanborg, Catharina and Schembri, Mark A. (2009) Virulence properties of asymptomatic bacteriuria Escherichia coli. International Journal of Medical Microbiology, 299 1: 53-63. doi:10.1016/j.ijmm.2008.06.003 97   44 Cited 44 times in Scopus44 0