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Chen, C, Zhang, J, Vincent, JD and Israel, JM (1990) 2 Types of Voltage-Dependent Calcium Current in Rat Somatotrophs Are Reduced by Somatostatin. Journal of Physiology-London, 425 29-42. 26   67
Zhao, Yu-Feng, Feng, Dan-Dan, Hernandez, Maria and Chen, Chen (2007) 3T3-L1 adipocytes induce dysfunction of MIN6 insulin-secreting cells via multiple pathways mediated by secretory factors in a co-culture system. Endocrine, 31 1: 52-60. doi:10.1007/s12020-007-0001-3 90   7 Cited 9 times in Scopus9 0
Zhao, Y. F., Zhu, Y. L. and Chen, C. (2004) 3T3-L1 adipocytes reduces Kir6.2 channel expression in MIN6 insulin-secreting cells in vitro. Sheng li xue bao (Acta physiologica Sinica), 56 2: 253-257. 74   Cited 1 times in Scopus1
Hong, Yeon-Hee, Nishimura, Yukihiko, Hishikawa, Daisuke, Tsuzuki, Hiroaki, Miyahara, Hisae, Gotoh, Chizu, Choi, Ki-Choon, Feng, Dan Dan, Chen Chen, Lee, Hong-Gu, Katoh, Kazuo, Roh, Sang-Gun and Sasaki, Shinichi (2005) Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43. Endocrinology, 146 12: 5092-5099. doi:10.1210/en.2005-0545 145   143 Cited 157 times in Scopus157 0
Huang, Lili, Tan, Hwee Y., Fogarty, Matthew J., Andrews, Zane B., Veldhuis, Johannes D., Herzog, Herbert, Steyn, Frederik J. and Chen, Chen (2014) Actions of NPY, and its Y1 and Y2 receptors on pulsatile growth hormone secretion during the fed and fasted state. Journal of Neuroscience, 34 49: 16309-16319. doi:10.1523/JNEUROSCI.4622-13.2014 18   0 Cited 0 times in Scopus0 1
Zhao, Yu-Feng, Pei, Jianming and Chen, Chen (2008) Activation of ATP-sensitive potassium channels in rat pancreatic beta-cells by linoleic acid through both intracellular metabolites and membrane receptor signalling pathway. Journal of Endocrinology, 198 3: 533-540. doi:10.1677/JOE-08-0105 131   16 Cited 14 times in Scopus14 0
Chen, Jiezhong, Zhao, Kong-Nan, Li, Rui, Shao, Renfu and Chen, Chen (2014) Activation of PI3K/Akt/mTOR pathway and dual inhibitors of PI3K and mTOR in endometrial cancer. Current Medicinal Chemistry, 21 26: 3070-3080. 39   1 Cited 2 times in Scopus2
Du, Lai-Ling, Xie, Jia-Zhao, Cheng, Xiang-Shu, Li, Xiao-Hong, Kong, Fan-Li, Jiang, Xia, Ma, Zhi-Wei, Wang, Jian-Zhi, Chen, Chen and Zhou, Xin-Wen (2013) Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi. Age, 36 2: 613-623. doi:10.1007/s11357-013-9592-1 27   3 Cited 2 times in Scopus2 0
Keating, Damien J and Chen, Chen (2005) Activin A stimulates catecholamine secretion from rat adrenal chromaffin cells: A new physiological mechanism. Journal of Endocrinology, 186 2: R1-R5. doi:10.1677/joe.1.06301 68   4 Cited 4 times in Scopus4 1
Wang, Li, Zhao, Yufeng, Gui, Baosong, Fu, Rongguo, Ma, Feng, Yu, Jun, Qu, Ping, Dong, Lei and Chen, Chen (2011) Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+](i) increase in pancreatic islet alpha-cells. Journal of Endocrinology, 210 2: 173-179. doi:10.1530/JOE-11-0132 65   11 Cited 14 times in Scopus14 0
Steyn, Frederik J. and Chen, Chen (2013). Adiponectin. In Abba J. Kastin (Ed.), Handbook of biologically active peptides 2nd ed. (pp. 983-989) Amsterdam, Netherlands: Academic Press/Elsevier. doi:10.1016/B978-0-12-385095-9.00130-5 63 3 Cited 0 times in Scopus0 0
Rao, J. R., Keating, D. J., Chen, C. and Parkington, H. C. (2012) Adiponectin increases insulin content and cell proliferation in MIN6 cells via PPAR gamma-dependent and PPAR gamma-independent mechanisms. Diabetes Obesity & Metabolism, 14 11: 983-989. doi:10.1111/j.1463-1326.2012.01626.x 72   8 Cited 9 times in Scopus9 1
Steyn, F. J., Boehme, F., Vargas, E., Wang, K., Parkington, H. C., Rao, J. R. and Chen, C. (2009) Adiponectin Regulate Growth Hormone Secretion Via Adiponectin Receptor Mediated Ca2+ Signalling in Rat Somatotrophs In Vitro. Journal of Neuroendocrinology, 21 8: 698-704. doi:10.1111/j.1365-2826.2009.01887.x 106   12 Cited 15 times in Scopus15 0
Zhao, Yufeng and Chen, Chen (2011). Adipsin as an adipokine. In Victor R. Preedy and Ross J. Hunter (Ed.), Adipokines (pp. 20-28) Enfield, NH, United States: Science Publishers. 88 3
Keating, Damien J., Chen, Chen and Pritchard, Melanie A. (2006) Alzheimer's disease and endocytic dysfunction: Clues from the Down syndrome-related proteins, DSCR1 and ITSN1. Ageing research reviews, 5 4: 388-401. doi:10.1016/j.arr.2005.11.001 167   23 Cited 34 times in Scopus34 3
Wagoner, PK, Chen, C, Worley, JF, Dukes, ID and Oxford, GS (1993) Amylin Modulates Beta-Cell Glucose Sensing Via Effects On Stimulus-Secretion Coupling. Proceedings of the National Academy of Sciences of the United States of America, 90 19: 9145-9149. doi:10.1073/pnas.90.19.9145 28   50 0
Hassouna, Rim, Zizzari, Philippe, Tomasetto, Catherine, Veldhuis, Johannes D., Fiquet, Oriane, Labarthe, Alexandra, Cognet, Julie, Steyn, Frederik, Chen, Chen, Epelbaum, Jacques and Tolle, Virginie (2014) An early reduction in GH peak amplitude in preproghrelin deficient male mice has a minor impact on linear growth. Endocrinology, 155 9: 3561-3571. doi:10.1210/en.2014-1126 22   0 Cited 0 times in Scopus0 0
Zhang, Xinli and Chen, Chen (2012) A new insight of mechanisms, diagnosis and treatment of diabetic cardiomyopathy. Endocrine, 41 3: 398-409. doi:10.1007/s12020-012-9623-1 181 4 9 Cited 11 times in Scopus11 0
Chu, Kwan Yi, Cheng, Qianni, Chen, Chen, Au, Lai Shan, Seto, Sai Wang, Tuo, Ya, Motin, Leonid, Kwan, Yiu Wa and Leung, Po Sing (2010) Angiotensin II exerts glucose-dependent effects on K-v currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors. American Journal of Physiology - Cell Physiology, 298 2: C313-C323. doi:10.1152/ajpcell.00575.2008 66   14 Cited 15 times in Scopus15 0
Chen, Jiezhong, Shao, Renfu, Zhang, Xu Dong and Chen, Chen (2013) Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics. International Journal of Nanomedicine, 8 2677-2688. doi:10.2147/IJN.S45429 28   8 Cited 11 times in Scopus11 3
Chen, C, Zhang, J, Dayanithi, G, Vincent, JD and Israel, JM (1989) Cationic Currents On Identified Rat Gonadotroph Cells Maintained in Primary Culture. Neurochemistry International, 15 3: 265-275. doi:10.1016/0197-0186(89)90132-0 23   17 0
Chen, Chen (2002). Cell biology and membrane function. In Textbook of Medical Physiology (pp. 7-26) China: People's Health Press. 59  
Zhao, Yu-Feng, Wang, Li, Lee, Soohyun, Sun, Qiang, Tuo, Ya, Wang, Yuemin, Pei, Jianming and Chen, Chen (2010) Cholesterol induces mitochondrial dysfunction and apoptosis in mouse pancreatic beta-cell line MIN6 cells. Endocrine, 37 1: 76-82. doi:10.1007/s12020-009-9275-y 148   3 Cited 4 times in Scopus4 0
Xu, Xiangbin, Ding, Fan, Pang, Jinjiang, Gao, Xue, Xu, Rong-Kun, Hao, Wei, Cao, Ji-Min and Chen, Chen (2012) Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. American Journal of Physiology Heart and Circulatory Physiology, 303 6: H703-H711. doi:10.1152/ajpheart.00257.2011 62   5 Cited 6 times in Scopus6 1
Chen, C, Wu, D and Clarke, IJ (1996) Commentary - Signal transduction systems employed by synthetic GH-releasing peptides in somatotrophs. Journal of Endocrinology, 148 3: 381-386. doi:10.1677/joe.0.1480381 25   53 Cited 62 times in Scopus62 0
Zhao, Yu-Feng, Feng, Dan Dan and Chen, Chen (2006) Contribution of adipocyte-derived factors to beta-cell dysfunction in diabetes. International Journal of Biochemistry & Cell Biology, 38 5-6: 804-819. doi:10.1016/j.biocel.2005.11.008 194   40 Cited 45 times in Scopus45 0
Steyn, F. J., Huang, L., Ngo, S. T., Leong, J. W., Tan, H. Y., Xie, T. Y., Parlow, A. F., Veldhuis, J. D., Waters, M. J. and Chen, C. (2011) Development of a method for the determination of pulsatile growth hormone secretion in mice. Endocrinology, 152 8: 3165-3171. doi:10.1210/en.2011-0253 85   22 Cited 24 times in Scopus24 0
Steyn F.J., Wan Y., Clarkson J., Veldhuis J.D., Herbison A.E. and Chen C. (2013) Development of a methodology for and assessment of pulsatile luteinizing hormone secretion in juvenile and adult male mice. Endocrinology, 154 12: 4939-4945. doi:10.1210/en.2013-1502 58   7 Cited 7 times in Scopus7 0
Lee, SH, Sun, J, Tuo, Y, Moriyama, Y and Chen, C (2010). Differential Distribution of FFA Receptors, GPR40 and GPR120, in Mouse Islet beta and alpha-Cells May Contribute to Islet Dysfunction in Obesity-Related Type 2 Diabetes.. In: ENDOCRINE REVIEWS. 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), San Diego CA, (S1651-S1651). JUN 19-22, 2010. 152   0
Roh, Sang-Gun, Doconto, Maria, Feng, Dan Dan and Chen, Chen (2006) Differential regulation of GHRH-receptor and GHS-receptor expression by long-term in vitro treatment of ovine pituitary cells with GHRP-2 and GHRH. Endocrine, 30 1: 55-62. doi:10.1385/ENDO:30:1:55 54   10 Cited 10 times in Scopus10 0
Roh, SG, Nie, GY, Loneragan, K, Gertler, A and Chen, C (2001) Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells. Endocrinology, 142 12: 5167-5171. doi:10.1210/en.142.12.5167 27   29 Cited 33 times in Scopus33 0
Chen, Chen and Sun, Qiang (2009) Discovery and research progress of ghrelin. Journal of Xi’an Jiaotong University (Medical Sciences), 30 2: 131-136. 84   Cited 0 times in Scopus0
Chen, Chen (2002) Discovery, progress and future of growth hormone releasing peptides. Basic medical sciences and clinics, 22 1-5. 44  
Zhao, Yu-Feng, Xu, Ruwei, Hernandez, Maria, Zhu, Yunlong and Chen Chen (2003) Distinct Intracellular Ca2+ Response to Extracellular Adenosine Triphosphate in Pancreatic -Cells in Rats and Mice. Endocrine, 22 3: 185-192. doi:10.1385/ENDO:22:3:185 44   8 Cited 9 times in Scopus9 0
Chen, C, Xu, RW, Clarke, IJ, Ruan, M, Loneragan, K and Roh, SG (2000) Diverse intracellular signalling systems used by growth hormone-releasing hormone in regulating voltage-gated Ca2+ or K+ channels in pituitary somatotropes. Immunology and Cell Biology, 78 4: 356-368. doi:10.1046/j.1440-1711.2000.00917.x 26   28 Cited 29 times in Scopus29 0
Smart, R., Kiely, A., Beale, M., Vargas, E., Carraher, C., Kralicek, A. V., Christie, D. L., Chen, C., Newcomb, R. D. and Warr, C. G. (2008) Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins. Insect Biochemistry and Molecular Biology, 38 8: 770-780. doi:10.1016/j.ibmb.2008.05.002 61   108 Cited 112 times in Scopus112 0
Keating, Damien J., Dubach, Daphne, Zanin, Mark P., Yu, Yong, Martin, Katherine, Zhao, Yu-Feng, Chen, Chen, Port, Sı´lvia, Arbone´s, Maria L., Mittaz, Laureane and Pritchard, Melanie A. (2008) DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: Implications for Down syndrome and Alzheimer's disease. Human Molecular Genetics, 17 7: 1020-1030. doi:10.1093/hmg/ddm374 104   38 Cited 40 times in Scopus40 0
Yan, M., Hernandez, M., Xu, R. and Chen, C. (2004) Effect of GHRH and GHRP-2 Treatment in Vitro on GH Secretion and Levels of GH, Pituitary Transcription Factor-1, GHRH-receptor, GH-secretagogue-receptor and Somatostatin Receptor mRNAs in Ovine Pituitary Cells. European Journal of Endocrinology, 150 2: 235-242. doi:10.1530/eje.0.1500235 72   16 Cited 18 times in Scopus18 0
Chen, C, Pullar, M, Loneragan, K, Zhang, J and Clarke, IJ (1998) Effect of growth hormone-releasing peptide-2 (GHRP-2) and GH-releasing hormone (GHRH) on the cAMP levels and GH release from cultured acromegalic tumours. Journal of Neuroendocrinology, 10 6: 473-480. doi:10.1046/j.1365-2826.1998.00233.x 27   9 Cited 11 times in Scopus11 0
Wu, DX, Chen, C, Zhang, J, Katoh, K and Clarke, I (1994) Effects In-Vitro of New Growth-Hormone Releasing Peptide (ghrp-1) On Growth-Hormone Secretion From Ovine Pituitary-Cells in Primary Culture. Journal of Neuroendocrinology, 6 2: 185-190. doi:10.1111/j.1365-2826.1994.tb00571.x 36   31 Cited 28 times in Scopus28 0
Cao, Ji-Min, Ong, Huy and Chen, Chen (2006) Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system. Trends in endocrinology and metabolism, 17 1: 13-18. doi:10.1016/j.tem.2005.11.004 52   36 Cited 42 times in Scopus42 0
Sun, Qiang, Ma, Yi, Zhang, Lin, Zhao, Yu-Feng, Zang, Wei-Jin and Chen, Chen (2010) Effects of GH secretagogues on contractility and Ca2+ homeostasis of isolated adult rat ventricular myocytes. Endocrinology, 151 9: 4446-4454. doi:10.1210/en.2009-1432 69 1 12 Cited 11 times in Scopus11 0
Chen, C and Clarke, IJ (1995) Effects of Growth Hormone-Releasing Peptide-2 (ghrp-2) On Membrane Ca2+ Permeability in Cultured Ovine Somatotrophs. Journal of Neuroendocrinology, 7 3: 179-186. doi:10.1111/j.1365-2826.1995.tb00745.x 13   23 0
Yan, M, Liu, DL, Chua, YL, Chen, C and Lim, YL (2001) Effects of micromolar concentrations of manganese, copper, and zinc on alpha(1)-adrenoceptor-mediating contraction in rat aorta. Biological Trace Element Research, 82 1-3: 159-166. doi:10.1385/BTER:82:1-3:159 34   8 Cited 9 times in Scopus9 0
Liu, Dong Ling, Yan, Ming, Chua, Yeow Leng, Chen, Chen and Lim, Yean Leng (2002) Effects Of Molybdenum, Silicon And Nickel On α1-Adrenoceptor-Induced Constriction Of Rat Isolated Aorta. Clinical and Experimental Pharmacology and Physiology, 29 5-6: 395-398. doi:10.1046/j.1440-1681.2002.03674.x 194   7 Cited 2 times in Scopus2 0
Chen, C, Israel, JM and Vincent, JD (1989) Electrophysiological Responses of Rat Pituitary-Cells in Somatotroph-Enriched Primary Culture to Human Growth-Hormone Releasing-Factor. Neuroendocrinology, 50 6: 679-687. doi:10.1159/000125299 16   48 0
Chen, C, Israel, JM and Vincent, JD (1989) Electrophysiological Responses to Somatostatin of Rat Hypophyseal Cells in Somatotroph-Enriched Primary Cultures. Journal of Physiology-London, 408 493-510. 22   46
Fung, Jenny N.T. and Chen, Chen (2012). Endometrial cancer: diagnosis, treatment and prevention. In Hiroto S. Watanabe (Ed.), Horizons in cancer research. Volume 49 (pp. 1-32) Hauppauge, NY, USA: Nova Publishers. 74  
Chen, C and Wagoner, PK (1991) Endothelin Induces a Nonselective Cation Current in Vascular Smooth-Muscle Cells. Circulation Research, 69 2: 447-454. 25   71
Cowley, MA, Chen, C and Clarke, IJ (1999) Estrogen transiently increases delayed rectifier, voltage-dependent potassium currents in ovine gonadotropes. Neuroendocrinology, 69 4: 254-260. doi:10.1159/000054426 25   11 0

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