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Ovchinnikov, Dmitry A., DeBats, Claire E. E., Sester, David P., Sweet, Matthew J. and Hume, David A. (2010) A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice. Journal of Leukocyte Biology, 87 5: 815-822. doi:10.1189/jlb.0809557 68   9 Cited 8 times in Scopus8 0
Irvine, Katharine M., Burns, Christopher J., Wilks, Andrew F., Su, Stephen, Hume, David A. and Sweet, Matthew J. (2006) A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations. The FASEB Journal, 20 11: 1921-1923. doi:10.1096/fj.06-5848fje 142   49 Cited 17 times in Scopus17 7
Robin, G., Cowieson, N.P., Guncar, G., Forwood, J.K., Listwan, P., Hume, D.A., Kobe, B., Martin, J.L. and Huber, T.L. (2008). A general target selection method for crystallographic proteomics. In Kobe, B., Guss, M. and Huber, T.L. (Ed.), Structural Proteomics: High-Throughput Methods 1st ed. (pp. 27-35) Totowa, NJ, USA: Humana Press. 70  
Himes, S. R., Tagoh, H., Goonetilleke, N., Sasmono, T., Oceandy, D., Clark, R., Bonifer, C. and Hume, D. A. (2001) A highly conserved c-fms gene intronic element controls macrophage-specific and regulated expression. Journal of Leukocyte Biology, 70 5: 812-820. 65   49
Wells, CA, Chalk, AM, Forrest, A, Taylor, D, Waddell, N, Schroder, K, Himes, SR, Faulkner, G, Lo, S, Kasukawa, T, Kawaji, H, Kai, C, Kawai, J, Katayama, S, Carninci, P, Hayashizaki, Y, Hume, DA and Grimmond, SM (2006) Alternate transcription of the Toll-like receptor signaling cascade. Genome Biology, 7 2: R10.1-R10.17. doi:10.1186/gb-2006-7-2-r10 77   32 Cited 40 times in Scopus40 0
Sasmono, R. T., Oceandy, D., Pollard, J. W., Tong, W., Pavli, P., Wainwright, B. J., Ostrowski, M. C., Himes, S. R. and Hume, D. A. (2003) A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood, 101 3: 1155-1163. doi:10.1182/blood-2002-02-1569 157   251 Cited 256 times in Scopus256 0
Cowieson, N. P., Wensley, B., Robin, G., Guncar, G., Forwood, J. K., Hume, D. A., Kobe, B. and Martin, J. L. (2008). A medium or high throughput protein refolding assay. In Bostjan Kobe, Mitchell Guss and Thomas Huber (Ed.), Structural Proteomics: High throughput Methods (pp. 269-275) USA: Humana Press. 87  
Teasdale, R. D., Hume, D. A., Yuan, Zheng and The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I & II Team (2002) Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature, 420 6915: 563-573. doi:10.1038/nature01266 66   833 Cited 875 times in Scopus875 3
Himes, S. R., Goonetilleke, N. P. and Hume, D. A. (1999). An anti-sense intronic promoter in the C-fms gene regulates expression in activated macrophages. In: Combined Conference Abstracts: 43rd Annual ASBMB, 18th Annual ANZSCDB and 39th Annual ASPP. ComBio 99, Conrad Jupiters, Gold Coast, (Sym-11-04). 27-30 September, 1999. 56  
Cowieson, Nathan P., Wensley, Beth, Listwan, Pawel, Hume, David A., Kobe, Bostjan and Martin, Jennifer L. (2006) An automatable screen for the rapid identification of proteins amenable to refolding. Proteomics, 6 6: 1750-1757. doi:10.1002/pmic.200500056 86   10 Cited 11 times in Scopus11 1
Aagaard, A., Listwan, P., Cowieson, N. P., Huber, T. L., Ravasi, T., Wells, C. A., Flanagan, J. U., Kellie, S., Hume, D. A., Kobe, B. and Martin, J. L. (2005) An inflammatory role for the mammalian carboxypeptidase inhibitor latexin: Relationship to cystatins and the tumor suppressor TIG1. Structure, 13 2: 309-317. doi:10.1016/j.str.2004.12.013 60   39 Cited 39 times in Scopus39 0
RIKEN GER Group,, Wells, C. A., Frith, M., Ravasi, T., Pang, K. C., Hallinan, J. S., Mattick, J. S., Hume, D. A., Katayama, S., Tomaru, Y., Kasukawa, T., Waki, K., Nakanishi, M., Nakamura, M. and Nishida, H. (2005) Antisense transcription in the mammalian transcriptome. Science, 309 5740: 1564-1566. doi:10.1126/science.1112009 289   750 Cited 760 times in Scopus760 7
Passey, Robert J., Williams, Elizabeth, Lichanska, Agnieszka M., Wells, Christine, Hu, Shengping, Geczy, Carolyn L., Little, Melissa H. and Hume, David A. (1999) A null mutation in the inflammation-associated S100 protein S100A8 causes early resorption of the mouse embryo. Journal of Immunology, 163 4: 2209-2216. 92   87
Henson, P. M. and Hume, D. A. (2006) Apoptotic cell removal in development and tissue homeostasis. Trends In Immunology, 27 5: 244-250. doi:10.1016/j.it.2006.03.005 121   170 Cited 171 times in Scopus171 0
Kakuda, D. K., Sweet, M. J., MacLeod, C. L., Hume, D. A. and Markovich, D. (1999) CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages. Biochemical Journal, 340 2: 549-553. doi:10.1042/0264-6021:3400549 49   73 Cited 78 times in Scopus78 0
Dave, R. K., Hume, D. A., Elsegood, C and Kellie, S (2009) CD148/DEP-1 association with areas of cytoskeletal organisation in macrophages. Experimental Cell Research, 315 10: 1734-1744. doi:10.1016/j.yexcr.2009.02.023 55   6 Cited 6 times in Scopus6 0
Mooney, Jane E., Rolfe, Barbara E., Osborne, Geoffrey W., Sester, David P., van Rooijen, Nico, Campbell, Gordon R., Hume, David A. and Campbell, Julie H. (2010) Cellular plasticity of inflammatory myeloid cells in the peritoneal foreign body response. American Journal of Pathology, 176 1: 369-380. doi:10.2353/ajpath.2010.090545 110   24 Cited 25 times in Scopus25 0
Rae, Fiona, Woods, Kyra, Sasmono, Tedjo, Campanale, Naomi, Taylor, Darrin, Ovchinnikov, Dmitry A., Grimmond, Sean M., Hume, David A., Ricardo, Sharon D. and Little, Melissa H. (2007) Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter. Developmental Biology, 308 1: 232-246. doi:10.1016/j.ydbio.2007.05.027 75   82 Cited 87 times in Scopus87 0
Hamwood, T., Kobe, B., Smythe, M. L. and Hume, D. A. (2002). Clues to interaction between CSF-1 and CSF-1R from specificity and structure. In: Australian Society of Immunologists Meeting. Australian Society of Immunologists Meeting, Brisbane, ((Poster)). 1-5 December, 2002. 56  
Irvine, Katharine M., Andrews, Melanie R., Fernandez-Rojo, Manuel A., Schroder, Kate, Burns, Christopher J., Su, Stephen, Wilks, Andrew F., Parton, Robert G., Hume, David A. and Sweet, Matthew J. (2009) Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages. Journal of Leukocyte Biology, 85 2: 278-288. doi:10.1189/jlb.0808497 77   28 Cited 30 times in Scopus30 0
Sweet, Matthew J., Campbell, Carol C., Sester, David P., Xu, Damo, McDonald, Rebecca C., Stacey, Katryn J., Hume, David A. and Liew, Foo Y. (2002) Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. Journal of Immunology, 168 1: 392-399. 62   76 Cited 75 times in Scopus75
Hume, David A. (2006) Comment on "CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes". Journal of Immunology, 177 4: 2035-2035. 155   2 Cited 1 times in Scopus1
Brahmachary, M., Schonbach, C., Yang, L., Huang, E. L., Tan, S. L., Chowdhary, R., Krishnan, S. P. T., Lin, C. Y., Hume, D. A., Kai, C., Kawai, J., Carninci, P., Hayashizaki, Y. and Bajic, V. B. (2006) Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes. Bmc Bioinformatics, 7 Supp. 5: Article number S8. doi:10.1186/1471-2105-7-S5-S8 83   17 Cited 17 times in Scopus17 0
Hinshelwood, Rebecca A., Huschtscha, Lily I., Melki, John, Stirzaker, Clare, Abdipranoto, Andrea, Vissel, Bryce, Ravasi, Timothy, Wells, Christine A., Hume, David A., Reddel, Roger R. and Clark, Susan J. (2007) Concordant Epigenetic silencing of transforming growth factor -beta signalling pathway genes occurs early in breast carcinogenesis. Cancer Research, 67 24: 11517-11527. doi:10.1158/0008-5472.CAN-07-1284 72   52 Cited 54 times in Scopus54 0
Schroder, Kate, Irvine, Katharine M., Taylor, Martin S., Bokil, Nilesh J., Le Cao, Kim-Anh, Masterman, Kelly-Anne, Labzin, Larisa I., Semple, Colin A., Kapetanovic, Ronan, Fairbairn, Lynsey, Akalin, Altuna, Faulkner, Geoffrey J., Baillie, John Kenneth, Gongora, Milena, Daub, Carsten O., Kawaji, Hideya, McLachlan, Geoffrey J., Goldman, Nick, Grimmond, Sean M., Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Lenhard, Boris, Hume, David A. and Sweet, Matthew J. (2012) Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the USA, 109 16: E944-E953. doi:10.1073/pnas.1110156109 98   37 Cited 43 times in Scopus43 3
Cassady, A. Ian, Stacey, Katryn J., Nimmo, Karen A., Murphy, Kathleen M., von der Ahe, Dietmar, Pearson, David, Botteri, Florence M., Nagamine, Yoshikuni and Hume, David A. (1991) Constitutive expression of the urokinase plasminogen activator gene in murine RAW264 macrophages involves distal and 5' non-coding sequences that are conserved between mouse and pig. Nucleic Acids Research, 19 24: 6839-6847. doi:10.1093/nar/19.24.6839 15   55 Cited 32 times in Scopus32 0
Kasukawa, T., Katayama, S., Kawaji, H., Suzuki, H., Hume, D. A. and Hayashizaki, Y. (2004) Construction of representative transcript and protein sets of human, mouse, and rat as a platform for their transcriptome and proteome analysis. Genomics, 84 6: 913-921. doi:10.1016/j.ygeno.2004.08.011 67   15 Cited 14 times in Scopus14 0
Wells, C. A., Ravasi, T., Sultana, R., Yagi, K., Carninci, P., Bono, H., Faulkner, G. J., Okazaki, Y., Quackenbush, J., Hume, D. A., RIKEN GER Group,, GSL Members, and Lyons, P. A. (2003) continued discovery of transcriptional units expressed in cells of the mouse mononuclear phagocyte lineage. Genome Research, 13 6B: 1360-1365. doi:10.1101/gr.1056103 67   30 Cited 32 times in Scopus32 0
Cowieson, Nathan P., King, Gordon, Cookson, David, Ross, Ian, Huber, Thomas, Hume, David A., Kobe, Bostjan and Martin, Jennifer L. (2008) Cortactin adopts a globular conformation and bundles actin into sheets. The Journal of Biological Chemistry, 283 23: 16187-16193. doi:10.1074/jbc.M708917200 75   18 Cited 19 times in Scopus19 0
Sester, D. P., Brion, K., Trieu, A., Goodridge, H. S., Roberts, T. L., Dunn, J., Hume, D. A., Stacey, K. J. and Sweet, M. J. (2006) CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. Journal of Immunology, 177 7: 4473-4480. 220   32 Cited 31 times in Scopus31
Sester, D. P., Beasley, S. J., Sweet, M. J., Stacey, K. J. and Hume, D. A. (1999). CpG DNA effects macrophage CSF-1 receptor cell surface expression, proliferation and survival. In: Innate Resistant to Infection, Society for Leukocyte Biology. 15th International Congress for Society for Leukocyte Biology, Churchill College, Cambridge UK, (). 22-26 September, 1999. 63  
Hamilton, S. E., Guddat, L. W., McAlpine, A. S., Hume, D. A., De Jersey, J. and Martin, J. L. (1999). Crystallisation of a mammalian purple acid phosphatase. In: 24th Annual Lorne Conference on Protein Structure and Function. 24th Annual Lorne Conference on Protein Structure and Functin, Erskine House, Lorne, Vic., (C10). 7-11 February, 1999. 58  
Serek, R., Forwood, J. K., Hume, D. A., Martin, J. L. and Kobe, B. (2006) Crystallization of the C-terminal domain of the mouse brain cytosolic long-chain acyl-CoA thioesterase. Acta Crystallographica Section F-structural Biology And Crystallization Communications, 62 133-135. doi:10.1107/S17443091060000030 52   4 Cited 4 times in Scopus4 0
Guddat, L. W., McAlpine, A. S., Hume, D. A., Hamilton, S. E, De Jersey, J. and Martin, J. L. (1999). Crystal structure of mammalian purple acid phosphatase: An enzyme with a binuclear metal centre. In: Combined Conference Abstracts: 43rd Annual ASBMB, 18th Annual ANZSCDB and 39th Annual ASPP. ComBio 99, Conrad Jupiters, Gold Coast, (Sym-05-01). 27-30 September, 1999. 62  
Sweet, MJ and Hume, DA (2003) CSF-1 as a regulator of macrophage activation and immune responses. Archivum Immunologiae Et Therapiae Experimentalis, 51 3: 169-177. 167   51 Cited 57 times in Scopus57
Roberts, T. L., Sweet, M. J., Hume, D. A. and Stacey, K. J. (2005) Cutting edge: Species-specific TLR9-mediated recognition of CpG and non-CpG phosphorothioate-modified ohgonucleotides. Journal of Immunology, 174 2: 605-608. 78   88 Cited 90 times in Scopus90
Kasukawa, T., Furuno, M., Nikaido, I., Bono, H., Hume, D. A., Bult, C., Hill, D. P., Baldarelli, R., Gough, J., Kanapin, A., Matsuda, H., Schriml, L. M., Hayashizaki, Y., Okazaki, Y. and Quackenbush, J. (2003) Development and evaluation of an automated annotation pipeline and cDNA annotation system. Genome Research, 13 6B: 1542-1551. doi:10.1101/gr.992803 59   21 Cited 26 times in Scopus26 0
Roberts, T. L., Dunn, J. A., Terry, T. D., Jennings, M. P., Hume, D. A., Sweet, M. J. and Stacey, K. J. (2005) Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides. Journal of Immunology, 175 6: 3569-3576. 58   44 Cited 41 times in Scopus41
Schroder, K., Spille, M., Pilz, A., Lattin, J., Bode, K. A., Irvine, K. M., Burrows, A. D., Ravasi, T., Weighardt, H., Stacey, K. J., Decker, T., Hume, D. A., Dalpke, A. H. and Sweet, M. J. (2007) Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells: Alternatively activated STAT1 negatively regulates TLR signaling in macrophages. Journal of Immunology, 179 6: 3495-3503. 159   29 Cited 28 times in Scopus28
Halili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010) Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 6: 1103-1114. doi:10.1189/jlb.0509363 116   52 Cited 55 times in Scopus55 0
McMorran, B., Town, L., Costelloe, E., Palmer, J., Engel, J., Hume, D. and Wainwright, B. (2003) Effector ExoU from the type III secretion system is an important modulator of gene expression in lung epithelial cells in response to Pseudomonas aeruginosa infection. Infection And Immunity, 71 10: 6035-6044. doi:10.1128/IAI.71.10.6035-6044.2003 124   23 Cited 23 times in Scopus23 0
Sweet, M. J. and Hume, D. A. (1996) Endotoxin signal transduction in macrophages. Journal of Leukocyte Biology, 60 1: 8-26. 19   530 Cited 553 times in Scopus553
Pickering, D., Hume, D. A. and Young, P. R. (2001). Enhanced protection of mice from challenge with dengue virus following immunization with recombinant NS1 and CpG oligonucleotides. In: 6th International Symposium on Positive Strand Viruses, Paris, France, ((Abstract)). 28 May - 2 June, 2001. 80  
Tagoh, Hiromi, Schebesta, Alexandra, Lefevre, Pascal, Wilson, Nicola, Hume, David, Busslinger, Meinrad and Bonifer, Constanze (2004) Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible. The EMBO Journal, 23 21: 4275-4285. doi:10.1038/sj.emboj.7600421 86   53 Cited 55 times in Scopus55 0
Ostrowski, M., Erbe, L. S., Hume, D. A. and Smith, J. L. (1999). ETS-2 is a target for a CSF-1-Independent AKT signaling pathway preventing apoptosis in macrophages of motheaten-viable mice. In: Combined Conference Abstratcs: 43rd Annual ASBMB, 18th Annual ANZSCDB and 39th Annual ASPP. ComBio 99, Conrad Jupiters, Gold Coast, (Sym-55-01). 27-30 September, 1999. 45  
Ravasi, T., Suzuki, H., Pang, K. C., Katayama, S., Furuno, M., Okunishi, R., Fukuda, S., Ru, K., Frith, M., Gongora, M., Grimmond, S., Hume, D. A., Hayashizaki, Y. and Mattick, J. S. (2006) Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome. Genome Research, 16 1: 11-19. doi:10.1101/gr.4200206 85   198 Cited 207 times in Scopus207 0
Ovchinnikov, Dmitry A., van Zuylen, Wendy J. M., DeBats, Claire E. E., Alexander, Kylie A., Kellie, Stuart and Hume, David A. (2008) Expression of Gal4-dependent transgenes in cells of the mononuclear phagocyte system labeled with enhanced cyan fluorescent protein using Csf1r-Gal4VP16/UAS-ECFP double-transgenic mice. Journal of Leukocyte Biology, 83 2: 430-433. doi:10.1189/jlb.0807585 87   22 Cited 23 times in Scopus23 0
Puri, M., Robin, G., Cowieson, N., Forwood, J. K., Listwan, P., Hu, S. H., Guncar, G., Huber, T., Kellie, S., Hume, D. A., Kobe, B. and Martin, J. L. (2006) Focusing in on structural genomics: The University of Queensland structural biology pipeline. Biomolecular Engineering, 23 6: 281-289. doi:10.1016/j.bioeng.2006.09.002 99   6 Cited 9 times in Scopus9 0
Mcmorran, B., Palmer, J., Lunn, D., Oceandy, D., Costelloe, E. O., Thomas, G., Hume, D. A. and Wainwright, B. J. (2001) G551D CF mice display an abnormal host response and have impaired clearance of Pseudomonas lung disease. AJP-Lung Cellular and Molecular Physiology, 281 3: 740-747. 79  
Thomas, Gordon R., Costelloe, E. A., Lunn, D. P., Stacey, K. J., Passey, R., McGlinn, E. C., McMorran, B. J., Ahadizadeh, A., Geczy, C. L., Wainwright, B. J. and Hume, D. A. (2000) G551D cystic fibrosis mice exhibit abnormal regulation of inflammation in lungs and macrophages. The Journal of Immunology, 164 7: 3870-3877. 65   40

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