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Halai, Reena, Croker, Daniel E., Suen, Jacky Y., Fairlie, David P. and Cooper, Matthew A. (2012) A comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly Gi coupled GPCR (C5aR) signalling. Biosensors, 2 3: 273-290. doi:10.3390/bios2030273 84   Cited 4 times in Scopus4 0
Reid, Robert C., Abbenante, Giovanni, Taylor, Stephen M. and Fairlie, David P. (2003) A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug. Journal of Organic Chemistry, 68 11: 4464-4471. doi:10.1021/jo034228r 230   33 Cited 33 times in Scopus33 0
Fairlie, DP, Wickramasinghe, WA, Byriel, KA and Taube, H (1997) Activation of thiourea bound through sulfur to pentaammineruthenium(III): Structure and reactivity. Inorganic Chemistry, 36 11: 2242-2243. doi:10.1021/ic9611397 67   11 Cited 13 times in Scopus13 0
Leung, D., Schroder, K., White, H., Fang, N. X., Stoermer, M. J., Abbenante, G., Martin, J. L., Young, P. R. and Fairlie, D. P. (2001) Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. Journal of Biological Chemistry, 276 49: 45762-45771. doi:10.1074/jbc.M107360200 142   125 Cited 149 times in Scopus149 0
Driver, Russell W., Hoang, Huy N., Abbenante, Giovanni and Fairlie, David P. (2009) A cyclic beta-strand tripeptide with an alpha-helix like CD spectrum. Organic Letters, 11 14: 3092-3095. doi:10.1021/ol901181b 91   10 Cited 11 times in Scopus11 0
Kelso, Michael J., Hoang, Huy N., Oliver, Warren, Sokolenko, Nikolai, March, Darren R., Appleton, Trevor G. and Fairlie, David P. (2003) A cyclic metallopeptide induces alpha helicity in short peptide fragments of thermolysin. Angewandte Chemie International Edition, 42 4: 421-424. doi:10.1002/anie.200390128 117   26 Cited 29 times in Scopus29 0
Marcon, L., Kozak, D., Battersby, B.J., Chappell, K., Fairlie, D., Young, P.R. and Trau, M. (2008) A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteases. Analytical Biochemistry, 2008 376: 151-153. doi:10.1016/j.ab.2008.01.034 59   11 Cited 12 times in Scopus12 0
Barry, GD, Le, GT and Fairlie, DP (2006) Agonists and antagonists of protease activated receptors (PARs). Current Medicinal Chemistry, 13 3: 243-265. doi:10.2174/092986706775476070 214   43 Cited 44 times in Scopus44 0
Beyer, Renee L., Kelso, Michael J., Reid, Robert C., Le, Giang T. and Fairlie, David P. (2006). Alpha helix induction in HIV REV34-50 by N-terminal nucleators. In: Chemical Engineering News: Abstracts-232nd ACS National Meeting. 232nd ACS National Meeting, San Francisco, CA, U.S.A., (55-55). 10-14 September, 2006. doi:10.1021/cen-v084n034.p055 44   0
Ma, M. T., Hoang, H. N., Beyer, R. L., Bryant, G. K., Appleton, T. G. and Fairlie, D. (2005). Alpha-helix induction in short peptides using metal clips. In: International Chemical Congress of Pacific Basin Societies (Pacifichem2005). International Chemical Congress of Pacific Basin Societies (Pacifichem2005), Honolulu, Hawaii, (xx-xx). 15 - 20 December 2005. 92  
Kelso, Michael J., Beyer, Renée L., Hoang, Huy N., Lakdawala, Ami S., Snyder, James P., Oliver, Warren V., Robertson, Tom A., Appleton, Trevor G. and Fairlie, David P. (2004) Alpha-turn mimetics: short peptide alpha-Helices composed of cyclic metallopentapeptide modules. Journal of The American Chemical Society, 126 15: 4828-4842. doi:10.1021/ja037980i 255   58 Cited 62 times in Scopus62 0
Fairlie, DP, Woo, TC, Wickramasinghe, WA and Willis, AC (1994) Amide-Iminol Tautomerism - Effect of Metalation. Inorganic Chemistry, 33 26: 6425-6428. doi:10.1021/ic00104a067 121   40 0
Eckle S.B.G., Birkinshaw R.W., Kostenko L., Corbett A.J., McWilliam H.E.G., Reantragoon R., Chen Z., Gherardin N.A., Beddoe T., Liu L., Patel O., Meehan B., Fairlie D.P., Villadangos J.A., Godfrey D.I., Kjer-Nielsen L., McCluskey J. and Rossjohn J. (2014) A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. Journal of Experimental Medicine, 211 8: 1585-1600. doi:10.1084/jem.20140484 11   2 Cited 3 times in Scopus3 2
Singh, Yogendra, Sharpe, Philip C., Hoang, Huy N., Lucke, Andrew J., McDowall, Alasdair W., Bottomley, Stephen P. and Fairlie, David P. (2011) Amyloid formation from an α-helical peptide bundle is seeded by 310-helix aggregates. Chemistry: A European Journal, 17 1: 151-160. doi:10.1002/chem.201002500 58   8 Cited 8 times in Scopus8 0
Harrison, R. S., Sharpe, P. C., Singh, Y. and Fairlie, D. P. (2007). Amyloid peptides and proteins in review. In S. G. Amara, B. Bamberg, T. Fleischmann, S. C. Gudermann, S. C. Hebert, R. Jahn, W. J. Lederer, R. Lill, A. Miyajima, S. Offermanns and R. Zechner (Ed.), Reviews of physiology, biochemistry and pharmacology (pp. 1-77) Berlin, Germany: Springer. doi:10.1007/112_2007_0701 206   75 Cited 76 times in Scopus76 0
Lohman, Rink-Jan, Cotterell, Adam J., Barry, Grant D., Liu, Ligong, Suen, Jacky Y., Vesey, David A. and Fairlie, David P. (2012) An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. The FASEB Journal, 26 7: 2877-2887. doi:10.1096/fj.11-201004 82   19 Cited 21 times in Scopus21 1
Abbenante, J., Leung, D., Bond, T. J. and Fairlie, D. P. (2000) An efficient Fmoc strategy for the rapid synthesis of peptide para-nitroanilides. Letters in Peptide Science, 7 6: 347-351. doi:10.1023/A:1013016323676 170   6 Cited 12 times in Scopus12 0
Woodruff, T. M., Shiels, I. A., Fairlie, D. and Taylor, S. M. (2001). A new C5a receptor antagonist inhibits monoarticular arthritis in the rat. In: Proceedings of the Complement Associated Diseases, Animal Models and Therapeutics Workshop. Complement Assoc. Diseases, Animal Models & Ther. Workshop, Santorini, Greece, (37-37). 10-14 October, 2001. 77  
Bogoyevitch, M. A and Fairlie, D. P (2007) A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding. Drug Discovery Today, 12 15-16: 622-633. doi:10.1016/j.drudis.2007.06.008 110   107 Cited 123 times in Scopus123 0
Strachan, A. J., Woodruff, T.M., Haaima, G., Fairlie, D. P. and Taylor, S. M. (2000) A new small molecule C5a receptor antagonist inhibits the reverse-passive arthus reaction and endotoxic shock in rats. Journal of Immunology, 164 4: 6560-6565. 116   80
Iyer, Abishek, Lim, Junxian, Poudyal, Hemant, Reid, Robert C., Suen, Jacky Y., Webster, Julie, Prins, Johannes B., Whitehead, Jonathan P., Fairlie, David P. and Brown, Lindsay (2012) An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats. Diabetes, 61 9: 2320-2329. doi:10.2337/db11-1179 81 3 5 Cited 6 times in Scopus6 1
Tan, Cindy S. E., Hobson-Peters, Jody M., Stoermer, Martin J., Fairlie, David P., Khromykh, Alexander A. and Hall, Roy A. (2013) An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein. Journal of General Virology, 94 Pt. 9: 1961-1971. doi:10.1099/vir.0.054395-0 35   3 Cited 3 times in Scopus3 0
Hohenhaus, Daniel M., Schaale, Kolja, Le Cao, Kim-Anh, Seow, Vernon, Iyer, Abishek, Fairlie, David P. and Sweet, Matthew J. (2013) An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation. Immunobiology, 218 11: 1345-1353. doi:10.1016/j.imbio.2013.07.001 44   2 Cited 1 times in Scopus1 1
Reid, Robert C., March, Darren R., Dooley, Michael J., Bergman, Doug A., Abbenante, Giovanni and Fairlie, David P. (1996) A novel bicyclic enzyme inhibitor as a consensus peptidomimetic for the receptor-bound conformations of 12 peptidic inhibitors of HIV-1 protease. Journal of The American Chemical Society, 118 36: 8511-8517. doi:10.1021/ja960433v 73   42 Cited 35 times in Scopus35 0
van den Brenk, Anna L., Fairlie, David P., Gahan, Lawrence R., Hanson, Graeme R. and Hambley, Trevor W. (1996) A novel potassium-binding hydrolysis product of ascidiacyclamide, a cyclic peptide isolated from the ascidian lissoclinum patella. Inorganic Chemistry, 35 5: 1095-1100. doi:10.1021/ic9504755 73   28 Cited 29 times in Scopus29 0
Vesey David A., Suen, Jacky Yung, Johnson, David W. and Fairlie, David (2010). A Novel Protease-Activated Receptor-2 Antagonist Targeting Inflammation and Proliferation in Human Renal Tubular Epithelial Cells. In: Kidney Week, American society of Nephrology, Denver Colorado USA, (78-78). November 16 - 21. 57  
Reid, R. C., Abbenante, G., March, D. R., Scanlon, M. and Fairlie, D. P. (1997) A novel strategy for the design of potent peptidomimetic inhibitors of proteolytic enzymes: Application to HIV-1 protease.. Abstracts of Papers of The American Chemical Society, 214 177-MEDI. 73   0
Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky, Liu, Ligong, Do, Anh T., Vesey, David A. and Fairlie, David P. (2012) Antagonism of protease-activated receptor 2 protects against experimental colitis.. Journal of Pharmacology and Experimental Therapeutics, 340 2: 256-265. doi:10.1124/jpet.111.187062 57   16 Cited 19 times in Scopus19 0
Woodruff, Trent M., Strachan, Anna J., Dryburgh, Nathan, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002) Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat. Arthritis and Rheumatism, 46 9: 2476-2485. doi:10.1002/art.10449 98   75 Cited 73 times in Scopus73 0
Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006) Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 11: 7000-7007. 122   17 Cited 19 times in Scopus19
Iyer, Abishek, Fenning, Andrew, Lim, Junxian, Le, Giang T, Reid, Robert C, Halili, Maria A, Fairlie, David P and Brown, Lindsay (2010) Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats. British Journal of Pharmacology, 159 7: 1408-1417. doi:10.1111/j.1476-5381.2010.00637.x 137   34 Cited 43 times in Scopus43 0
Reantragoon, Rangsima, Corbett, Alexandra J., Sakala, Isaac G., Gherardin, Nicholas A., Furness, John B., Chen, Zhenjun, Eckle, Sidonia B. G., Uldrich, Adam P., Birkinshaw, Richard W., Patel, Onisha, Kostenko, Lyudmila, Meehan, Bronwyn, Kedzierska, Katherine, Liu, Ligong, Fairlie, David P., Hansen, Ted H., Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James and Kjer-Nielsen, Lars (2013) Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. Journal of Experimental Medicine, 210 11: 2305-2320. doi:10.1084/jem.20130958 34   22 Cited 19 times in Scopus19 11
Sumanadasa, Subathdrage D. M., Goodman, Christopher D., Lucke, Andrew J., Skinner-Adams, Tina, Sahama, Ishani, Haque, Ashraful, Do, Tram Anh, McFadden, Geoffrey I., Fairlie, David P. and Andrews, Katherine T. (2012) Antimalarial activity of the anticancer histone deacetylase inhibitor SB939. Antimicrobial Agents and Chemotherapy, 56 7: 3849-3856. doi:10.1128/AAC.00030-12 63   15 Cited 15 times in Scopus15 0
Andrews, Kathy T., Walduck, Anna, Kelso, Mike J., Fairlie, David P., Saul, Allan and Parsons, Peter G. (2000) Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents Anna Walduck, Mike J. Kelso, David P. Fairlie, Allan Saul, Peter G. Parsons. International Journal for Parasitology, 30 6: 761-768. doi:10.1016/S0020-7519(00)00043-6 155   74 0
Wheatley, Nicole C., Andrews, Katherine T., Tran, Truc L., Lucke, Andrew J., Reid, Robert C. and Fairlie, David P. (2010) Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components. Bioorganic & Medicinal Chemistry Letters, 20 23: 7080-7084. doi:10.1016/j.bmcl.2010.09.096 116   14 Cited 15 times in Scopus15 0
Glenn, MP, Kahnberg, P, Boyle, GM, Hansford, KA, Hans, D, Martyn, AC, Parsons, PG and Fairlie, DP (2004) Antiproliferative and phenotype-transforming antitumor agents derived from cysteine. Journal of Medicinal Chemistry, 47 12: 2984-2994. doi:10.1021/jm030222i 61   23 Cited 25 times in Scopus25 0
Qiu, L., Kelso, M., Hansen, C., West, M. L., Fairlie, D. and Parsons, P. (1999) Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate.. British Journal of Cancer, 80 8: 1252-1258. doi:10.1038/sj.bjc.6690493 35   84 Cited 104 times in Scopus104 0
Liebscher, S., Chappell, K.J., Stoermer, M.J., Fairlie, D.P. and Young, P.R (2009). Antiviral activity in cell culture of potent inhibitors targeting the West Nile Virus NS2B/NS3 protease. In: 6th General Meeting of the International Proteolysis Society, Gold Coast , QLD, Australia, (102-102). 26-30 October, 2009. 65  
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Newman, Michelle L., Ross, Paul A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2005) A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. International Immunopharmacology, 5 5: 883-892. doi:10.1016/j.intimp.2005.01.003 87   21 Cited 26 times in Scopus26 0
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2003) A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. Journal of Immunology, 171 10: 5514-5520. 89   72 Cited 71 times in Scopus71
Cherny, R. A., Legg, J. T., McLean, C. A., Fairlie, D., Huang, X., Atwood, C.S., Beyreuther, K., Tanzi, R. E., Masters, C. L. and Bush, A. (1999) Aqueous Dissolution of Alzheimer's Disease Ab Amyloid Deposits by Biometal Depletion. Journal of Biological Chemistry, 274 33: 23223-23228. doi:10.1074/jbc.274.33.23223 100   339 Cited 355 times in Scopus355 0
Barry, Grant D., Suen, Jacky Y., Low, Heng Boon, Pfeiffer, Bernhard, Flanagan, Bernadine, Halili, Maria, Le, Giang T. and Fairlie, David P. (2007) A refined agonist pharmacophore for protease activated receptor 2. Bioorganic & Medicinal Chemistry Letters, 17 20: 5552-5557. doi:10.1016/j.bmcl.2007.08.026 106   8 Cited 8 times in Scopus8 0
Arumugam, T. V., Shiels, I. A., Strachan, A. J., Abbenante, G., Fairlie, D. P. and Taylor, S. M. (2003) A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats. Kidney International, 63 1: 134-142. doi:10.1046/j.1523-1755.2003.00737.x 115   100 Cited 107 times in Scopus107 0
Stoermer, Martin J., Leung, Donmienne, Young, Paul R. and Fairlie, David P. (2009) Base-sensitivity of arginine alpha-ketoamide inhibitors of serine proteases. Australian Journal of Chemistry, 62 9: 988-992. doi:10.1071/CH09150 118   1 Cited 1 times in Scopus1 0
Loughlin, WA, Tyndall, JDA, Glenn, MP and Fairlie, DP (2004) Beta-strand mimetics. Chemical Reviews, 104 12: 6085-6117. doi:10.1021/cr040648k 60   137 Cited 137 times in Scopus137 0
Glenn, MP, Pattenden, LK, Reid, RC, Tyssen, DP, Tyndall, JDA, Birch, CJ and Fairlie, DP (2002) beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activity. Journal of Medicinal Chemistry, 45 2: 371-381. doi:10.1021/jm010414i 111   43 Cited 44 times in Scopus44 0
Hollenberg, M. D., Mihara, K., Polley, D., Suen, J. Y., Han, A., Fairlie, D. P. and Ramachandran, R. (2014) Biased signalling and proteinase-activated receptors (PARs): Targeting inflammatory disease. British Journal of Pharmacology, 171 5: 1180-1194. doi:10.1111/bph.12544 15   6 Cited 5 times in Scopus5 0
Van den Brenk, Anna L., Fairlie, David P., Hanson, Graeme R., Gahan, Lawrence R., Hawkins, Clifford J. and Jones, Alun (1994) Binding of copper(II) to the cyclic octapeptide patellamide D. Inorganic Chemistry, 33 10: 2280-2289. doi:10.1021/ic00088a034 59   52 Cited 48 times in Scopus48 0
Hansen, C., Ablett, E., Green, A., Sturm, R. A., Dunn, I. S., Fairlie, D. P., West, M. L. and Parsons, P. G. (1997) Biphasic response of the metallothionein promoter to ultraviolet radiation in human melanoma cells. Photochemistry and Photobiology, 65 3: 550-555. doi:10.1111/j.1751-1097.1997.tb08603.x 28   13 Cited 15 times in Scopus15 0
Croker, Daniel E., Halai, Reena, Fairlie, David P. and Cooper, Matthew A. (2013) C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2. Immunology and Cell Biology, 91 10: 625-633. doi:10.1038/icb.2013.48 32   2 Cited 5 times in Scopus5 0

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