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Cheung, T. K. and Florin, T. H. J. (2003) 6-thioguanine: A new old drug to procure remission in inflammatory bowel disease. Internal Medicine Journal, 33 1-2: 44-46. doi:10.1046/j.1445-5994.2003.00321.x 120   10 Cited 11 times in Scopus11 0
Heazlewood, Chad K., Cook, Matthew C., Eri, Rajaraman, Price, Gareth R., Tauro, Sharyn B., Taupin, Douglas, Thornton, David J., Png, Chin Wen, Crockford, Tanya L., Cornall, Richard J., Adams, Rachel, Kato, Masato, Nelms, Keats A., Hong, Nancy A., Florin, Timothy H. J., Goodnow, Christopher C. and McGuckin, Michael A. (2008) Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Medicine, 5 3: 440-460. doi:10.1371/journal.pmed.0050054 459   53 Cited 227 times in Scopus227 1
Florin, THJ (1997) Alkyl halides, super hydrogen production and the pathogenesis of pneumatosis cystoides coli. Gut, 41 6: 778-784. 92   15
Florin, T. H. (2003). Americans get wise on immunosuppression and infliximab. In: DDW Conference Correspondent Project 2003: 2 ; 1. Digestive Disease Week 2003, Orlando, Florida, (). 18 - 21 May, 2003. 67  
Hume, G. E., Fowler, E. V., Lincoln, D., Eri, R., Templeton, D., Florin, T. H., Cavanaugh, J. A. and Radford-Smith, G. (2006) Angiotensinogen and transforming growth factor beta 1 ; novel genes in the pathogenesis of Crohn's disease. Journal of Medical Genetics, 43 10: 1-5. doi:10.1136/jmg.2005.040477 109   13 Cited 16 times in Scopus16 0
Eri, R. D., Adams, R. J., Tran, T. V., Tong. H., Das. I., Roche, D. K., Oancea, I., Png, C. W., Jeffery, P. L., Radford-Smith, G.L., Cook, M. C., Florin, T. H. and McGuckin, M. A. (2011) An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity. Mucosal Immunology, 4 3: 354-364. doi:10.1038/mi.2010.74 131   23 Cited 31 times in Scopus31 0
Oancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013) A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 4: 594-605. doi:10.1136/gutjnl-2012-302274 88   5 Cited 7 times in Scopus7 3
Burger, Daniel C., Lawrance, Ian C., Bampton, Peter A., Prosser, Ruth, Croft, Anthony, Gilshenan, Kristen, Radford-Smith, Graham L. and Florin, Timothy H. (2010) Anti-tumour necrosis factor-alpha treatment for perianal Crohn's disease in Australia. Medical Journal of Australia, 192 7: 375-377. 78   1 Cited 1 times in Scopus1
Edwards, J., Watson, M., Roberts, R. A., Radford-Smith, G. L., Florin, T. H., Green, A., Newmann, B. and Purdie, D. (2000). Appendicectomy in IBD; evidence for a protective role strongly related to age in both ulcerative colitis and Crohns disease. In: Australian Gastroenterology Week. Australian Gastroenterology Week, Hobart, (J10). October. 82  
Florin, T. H., Cayzer, C., Purdie, D. M., Fawcett, J. and Radford-Smith, G. L. (2001). Appendicectomy, primary sclerosing cholangitis and ulcerative colitis. In: Journal of Gastroenterology and Hepatology. Asia Pacific Digestive Week 2001, Sydney, (A4-A4). 23-27 Sept 2001. 174  
Mortimore, M and Florin, THJ (2010) A role for B-12 in inflammatory bowel disease patients with suppurative dermatoses? An experience with high dose vitamin B-12 therapy. Journal of Crohns and Colitis, 4 4: 466-470. doi:10.1016/j.crohns.2010.02.007 250   1 Cited 3 times in Scopus3 2
Edwards, J. E., Florin, T. H., Green, A, Martin, N. G., Newman, B., Pandeya, N., Purdie, D. M., Radford-Smith, G. L. and Watson, M. (2003) A role for the appendix in inflammatory bowel disease? Cut it out. Gastroenterology, 125 4: 1270-1272. doi:10.1016/j.gastro.2003.05.002 108   Cited 1 times in Scopus1 0
Norris, R., Duley, J., Esmail, L., George, R. and Florin, T. (2013). Assay of the Thiopurine Nucleotides for TDM Using HPLC-MS/MS Compared to HPLC-UV in Whole Blood. In: Abstracts of the 13th International Congress Of Therapeutic Drug Monitoring and Clinical Toxicology. 13th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology, Salt Lake City, UT United States, (732-732). 22 - 26 September 2013. doi:10.1097/FTD.0b013e3182a8ef2b 22   0 0
Teml, A., Schwab, M., Hommes, D. W., Almer, S., Lukas, M., Feichtanschlager, T., Florin, T. H., Seiderer, J., Petritsch, W., Bokemeyer, B., Kreisel, W., Herrlinger, K. R., Knoflach, P., Bonaz, B,, Klugmann, T., Herfarth, H., Pedarnig, N. and Reinisch, W. (2007) A systematic survey evaluating 6-thioguanine-related hepatotoxicity in patients with inflammatory bowel disease. Wiener Klinische Wochenschrift (The Middle European Journal of Medicine), 119 17-18: 519-526. doi:10.1007/s00508-007-0841-0 73   21 Cited 22 times in Scopus22 0
Fowler, Elizabeth V., Doecke, James, Simms, Lisa A., Zhao, Zhen Zhen, Webb, Penelope M., Hayward, Nicholas K., Whiteman, David C., Florin, Timothy H., Montgomery, Grant W., Cavanaugh, Juleen A. and Radford-Smith, Graham L. (2008) ATG16L1 T300A shows strong associations with disease subgroups in a large Australian IBD population: Further support for significant disease heterogeneity. The American Journal of Gastroenterology, 103 10: 2519-2526. doi:10.1111/j.1572-0241.2008.02023.x 99   34 Cited 40 times in Scopus40 0
Duley, John and Florin, Timothy H.J. (2008) Azathioprine: When less is more. Journal Gastroenterology and Hepatology, 23 9: 1317-1319. doi:10.1111/j.1440-1746.2008.05564.x 52   2 Cited 2 times in Scopus2 0
Florin, T. H. (2005) Bacteria in pathogenesis and treatment of IBD. Wiener Medizinische Wochenschrift, 38 16: 10-11. 46  
Florin, T. H., Vuckovic, S., Patel, K., Webb, N. A., Hamilton, I., Hill, G.R. and Hart, D.N.J. (1999). Blood dendritic cell counts are reduced in some inflammatory bowel diseases. In: Blood: Abstracts of the 41st annual meeting of the American Society of Hematology (ASH). 41st annual meeting of the American Society of Hematology (ASH), New Orleans, Louisiana, (39B-39B). December, 1999. 40  
Eri, R, Jonsson, JR, Pandeya, N, Purdie, DM, Clouston, AD, Martin, N, Duffy, D, Powell, EE, Fawcett, J, Florin, THJ and Radford-Smith, GL (2004) CCR5-Delta 32 mutation is strongly associated with primary sclerosing cholangitis. Genes And Immunity, 5 6: 444-450. doi:10.1038/sj.gene.6364113 413   34 Cited 45 times in Scopus45 1
Vuckovic, S, Florin, THJ, Khalil, D, Zhang, MF, Patel, K, Hamilton, I and Hart, DNJ (2001) CD40 and CD86 upregulation with divergent CMRF44 expression on blood dendritic cells in inflammatory bowel diseases. American Journal of Gastroenterology, 96 10: 2946-2956. doi:10.1016/S0002-9270(01)03248-8 90   49 Cited 52 times in Scopus52 0
Edwards, J. T., Radford-Smith, G. L. and Florin, T. H. J. (2001) Chronic narcotic use in inflammatory bowel disease patients: Prevalence and clinical characteristics. Journal of Gastroenterology And Hepatology, 16 11: 1235-1238. doi:10.1046/j.1440-1746.2001.02468.x 126   27 Cited 31 times in Scopus31 7
Florin, TH, Vuckovic, S, Patel, K, Khalil, D, Webb, N and Hart, DN (2000) Circulating dendritic cells are reduced in patients with active ulcerative colitis but not in patients with active Crohn's disease.. Gastroenterology, 118 4: A343-A343. 46   0
Florin, THJ, Paterson, EWJ, Fowler, EV and Radford-Smith, GL (2006) Clinically active Crohn's disease in the presence of a low C-reactive protein. Scandinavian Journal of Gastroenterology, 41 3: 306-311. doi:10.1080/00365520500217118 265   42 Cited 51 times in Scopus51 0
Selby, W.S., Crotty, B., Florin, T. H. and Pavli, P. (2001). Combination anti-paratuberculosis therapy with clarithromycin, rifabutin and clofazimine in the treatment of Crohn's disease. A preliminary report on the Australian multicentre trial. In: Journal of Gastroenterology ad Hepatology. Asia Pacific Digestive Week 2001, Sydney, (A8-A8). 23-27 Sept 2001. 90  
Wang, X., Krause, D, Heazlewood, S. and Florin, T. H. (2001). Comparative analysis of the mucosal associated microbiota in Crohn's disease and non-BD control subjects. In: Journal of Gastroenterology and Hepatology. Asia Pacific Digestive Week 2001, Sydney, (A9-A9). 23-27 Sept 2001. 57  
Gibson, P. R., Fixa, B., Pekarkova, B., Batovsky, M., Radford-Smith, G., Tibitanzl, J., Gabalec, L., Florin, T. H. J. and Greinwald, R. (2006) Comparison of the efficacy and safety of Eudragit-L-coated mesalazine tablets with ethylcellulose-coated mesalazine tablets in patients with mild to moderately active ulcerative colitis. Alimentary Pharmacology & Therapeutics, 23 7: 1017-1026. doi:10.1111/j.1365-2036.2006.02861.x 122   17 Cited 22 times in Scopus22 0
Florin, T. H. (2000). COX-2 inhibitors a major therapeutical advance. In: DDW Conference Correspondent Project. American Gastroenterology Association DDW, San Diego USA, (1). May 2000. 35  
De Cruz, Peter, Kamm, Michael A., Hamilton, Amy L., Ritchie, Kathryn J., Krejany, Efrosinia O., Gorelik, Alexandra, Liew, Danny, Prideaux, Lani, Lawrance, Ian C., Andrews, Jane M., Bampton, Peter A., Gibson, Peter R., Sparrow, Miles, Leong, Rupert W., Florin, Timothy H., Gearry, Richard B., Radford-Smith, Graham, Macrae, Finlay A., Debinski, Henry, Selby, Warwick, Kronborg, Ian, Johnston, Michael J., Woods, Rodney, Elliott, P. Ross, Bell, Sally J., Brown, Steven J., Connell, William R. and Desmond, Paul V. (2015) Crohn's disease management after intestinal resection: a randomised trial. The Lancet, 385 9976: 1406-1417. doi:10.1016/S0140-6736(14)61908-5 12   Cited 0 times in Scopus0 50
McGuckin, M. A., Das, I., Png, C. W., Tran, T., Eri, R., Lourie, R., Adams, R., Crane, D. and Florin, T. H. (2010). Dexamethasone ameliorates intestinal epithelial cell ER stress and ER stress induced colitis. In: Australian Gastroenterology Week 2010, Broadbeach, Qld., Australia, (A81-A82). 20-23 October 2010. doi:10.1111/j.1440-1746.2010.06454.x 71   0 0
Adams, Rachael, McGuckin, Michael and Florin, Timothy (2009) Dietary Antigens in Crohn's Disease. The American Journal of Gastroenterology, 104 2: 526-526. doi:10.1038/ajg.2008.79 49 12 1 Cited 0 times in Scopus0 0
van Asseldonk, Dirk P., Sanderson, Jeremy, de Boer, Nanne K.H., Sparrow, Miles P., Lemann, Marc, Ansari, Azhar, Almer, Sven H., Florin, Timothy H.J., Gearry, Richard B., Mulder, Chris J., Mantzaris, Gerassimos and van Bodegraven, Ad A. (2011) Difficulties and possibilities with thiopurine therapy in inflammatory bowel disease - Proceedings of the first Thiopurine Task Force meeting. Digestive and Liver Disease, 43 4: 270-276. doi:10.1016/j.dld.2010.09.001 58   16 Cited 14 times in Scopus14 0
Florin, T. H. J. (2006). Disturbances in microbiota - cause or effect?. In Fraser, A., Gibson, P. R., Hibi, T., Qian, J. M. and Scholmerich, J. (Ed.), Emerging Issues in Infammatory Bowel Diseases (pp. 79-82) Sydney: Springer. 34  
Florin, T. (2007). Disturbances in microbiota - cause or effect?. In: A. Fraser, P. R. Gibson, T. Hibi, J.-M. Qian and J. Schölmerich, Falk Symposium. Emerging Issues in Inflammatory Bowel Diseases. Falk Symposium 151: Emerging Issues in Inflammatory Bowel Diseases, Sydney, NSW, Australia, (79-82). 24-25 March 2006. 104   0
Florin, T. H., Vuckovic, S., Khalil, D., Brown, L. and Hart, D. N. J. (2000). Divergent expression of CMRF44 on blood dendritic cells of UC & CD patients & upregulation of CD40 & CD86. In: Australian Gastroenterology Week. Australian Gastroenterology and Hepatology, Hobart, Australia, (J28-J28). October 2000. 37  
Duley, JA, Marinaki, AM, Arenas, M and Florin, THJ (2006) Do ITPA and TPMT genotypes predict the development of side effects to AZA?. Gut, 55 7: 1048-1048. 38   4 Cited 6 times in Scopus6
Mortimore, M., Gibson, P. R., Selby, W. S., Radford-Smith, G. L. and Florin, T. H. J. (2001) Early Australian experience with infliximab, a chimeric antibody against tumour necrosis factor-alpha, in the treatment of Crohn's disease: is its efficacy augmented by steroid-sparing immunosuppressive therapy?. Internal Medicine Journal, 31 3: 146-150. doi:10.1046/j.1445-5994.2001.00039.x 122   34 Cited 38 times in Scopus38 0
Cayzer, C., Patel, K., Wang, X. and Florin, T. H. (2001). Effect of probiotics on Th1 and Th2 cytokines: Relevance to pathogenesis and treatment of ulcerating colitis. In: Journal of Gastroenterology & Hepatology. Asia Pacific Digestive Week 2001, Sydney, (A12-A12). 23-27 Sept 2001. 115  
Florin, T. H. J., Pandeya, N. and Radford-Smith, G. L. (2004) Epidemiology of appendicectomy in primary sclerosing cholangitis and ulcerative colitis: Its influence on the clinical behaviour of these diseases. Gut, 53 7: 973-979. doi:10.1136/gut.2003.036483 138   21 Cited 33 times in Scopus33 0
McGuckin, Michael A., Eri, Rajaraman D., Das, Indrajit, Lourie, Rohan and Florin, Timothy H. (2010) ER stress and the unfolded protein response in intestinal inflammation. American Journal of Physiology: Gastrointestinal and Liver Physiology, 298 6: G820-G832. doi:10.1152/ajpgi.00063.2010 92   46 Cited 53 times in Scopus53 2
Doecke, James D., Simms, Lisa A., Zhao, Zhen Zhen, Huang, Ning, Hanigan, Katherine, Krishnaprasad, Krupa, Roberts, Rebecca L., Andrews, Jane M., Mahy, Gillian, Bampton, Peter, Lewindon, Peter, Florin, Timothy, Lawrance, Ian C., Gearry, Richard B., Montgomery, Grant W. and Radford-Smith, Graham L. (2013) Genetic susceptibility in IBD: overlap between ulcerative colitis and Crohn's disease. Inflammatory Bowel Diseases, 19 2: 240-245. doi:10.1097/MIB.0b013e3182810041 82   7 Cited 7 times in Scopus7 9
Franke, Andre, McGoven, Demot P. B., Barrett,Jeffrey C., Wangs, Kai, Radford-Smith, Graham L., Ahmad, Tariq, Lees, Charlie W., Balschun, Tobias, Lee, James, Roberts, Rebecca, Anderson, Carl A., Bis, Joshua C., Bumpstead,Suzanne, Ellinghaus, David, Festen, Eleonora M., Georges, Michel, Green, Todd, Haritunians, Talin, Jostinm, Luke, Latiano, Anna, Mathew, Christopher G., Montgomery, Grant, Prescott, Natalie J., Raychaudhuri, Soumya, Rotter.Jerome I., Schumm, Philip, Sharma,Yashoda, Simms, Lisa A., Taylor, Kent D,, Whiteman, David, Wijmenga, Cisca, Baldassano, Robert N., Barclay, Murray, Bayless. Theodore M., Brand, Stephan, Buning, Carsten, Cohen, Albert, Colombel, Jean-Frederick, Cottone, Mario, Stronati, Laura, Denson, Ted, De Vos, Martine, D'Inca, Renata, Dubinsky. Marla, Edwards, Cathryn, Florin, Tim, Franchimont, Denis, Gearry, Richard, Glas, Jurgen, Van Gossum, Andre, Guthery, Stephen L., Halfvarson, Jonas, Verspaget, Hein W., Hugot, Jean-Pierre, Karban, Amir, Laukens, Debby, Lawrance, Ian, Lemann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, Mowat, Craig, Newman, William, Panes, Julian, Phillips. Anne, Proctor, Deborah D., Regueiro, Miguel, Russell , Richard, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Seibold, Frank, Steinhart, A. Hillary, Stokkers, Pieter C. F., Torkvist, Leif, Kullak-Ublick, Gerd, Wilson, David, Walters, Thomas, Targan,Stephan R., Brant, Steven R., Rioux, John D., D'Amato, Mauro, Weersma, Rinse K., Kugathasan, Subra, Griffiths, Anne M., Mansfield, John C., Vermeire, Severine, Duerr, Richard H., Silverberg, Mark S., Satsangi, Jack, Schreiber, Stefan, Cho, Judy H., Annese, Vito, Hakonarson, Hakon, Daly, Mark J. and Parkes, Miles P (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn’s disease susceptibility loci. Nature Genetics, 42 12: 1118-1125. doi:10.1038/ng.717 165   797 Cited 852 times in Scopus852 23
Das, Indrajit, Png, Chin Wen, Oancea, Iulia, Hasnain, Sumaira Z., Lourie, Rohan, Proctor, Martina, Eri, Rajaraman D., Sheng, Yong, Crane, Denis I., Florin, Timothy H. and McGuckin, Michael A. (2013) Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. Journal of Experimental Medicine, 210 6: 1201-1216. doi:10.1084/jem.20121268 67   5 Cited 6 times in Scopus6 5
Burger, D. C. and Florin, T. H. J. (2009) Hepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease.. Medical Journal of Australia, 190 6: 341-342. 70 49 Cited 6 times in Scopus6
Heap, Graham A., Weedon, Michael N., Bewshea, Claire M., Singh, Abhey, Chen, Mian, Satchwel, Jack B., Vivian, Julian P., So, Kenji, Dubois, Patrick C., Andrews, Jane M., Annese, Vito, Bampton, Peter, Barnardo, Martin, Bell, Sally, Cole, Andy, Connor, Susan J., Creed, Tom, Cummings, Fraser R., D'Amato, Mauro, Daneshmend, Tawfique K., Fedorak, Richard N., Florin, Timothy H., Gaya, Daniel R., Greig, Emma, Halfvarson, Jonas, Hart, Alisa, Irving, Peter M., Jones, Gareth, Karban, Amir, Lawrance, Ian C., Lee, James C., Lees, Charlie, Lev-Tzion, Raffi, Lindsay, James, Mansfield, John, Mawdsley, Joel, Mazhar, Zia, Parkes, Miles, Parnell, Kirstie, Orchard, Timothy R., Radford-Smith, Graham, Russell, Richard K., Reffitt, David, Satsangi, Jack, Silverberg, Mark S., Sturniolo, Giacomo C., Tremelling, Mark, Tsianos, Epameinondas V., van Heel, David A., Walsh, Alissa, Watermeyer, Gill, Weersma, Rinse K., Zeissig, Sebastian, Rossjohn, Jamie, Holden, Arthur L. and Ahmad, Tariq (2014) HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants. Nature Genetics, 46 10: 1131-1134. doi:10.1038/ng.3093 18   3 Cited 1 times in Scopus1 45
Florin, T. H. and Taylor, D. (2000) Hypothesis testing by X chromosome inactivation patterns may be more informative with lineage-specific cells. Molecular Human Reproduction, 6 2: 197-198. doi:10.1093/molehr/6.2.197 34   0 0
Adams, Rachel J., Heazlewood, Sharise P., Gilshenan, Kristen S., O'Brien, Mark, McGuckin, Michael A. and Florin, Timothy H. J. (2008) IgG Antibodies Against Common Gut Bacteria Are More Diagnostic for Crohn's Disease Than IgG Against Mannan or Flagellin. American Journal of Gastroenterology, 103 2: 386-396. doi:10.1111/j.1572-0241.2007.01577.x 95   30 Cited 31 times in Scopus31 1
Hasnain, Sumaira Z., Tauro, Sharyn, Das, Indrajit, Tong, Hui, Chen, Alice C. -H., Jeffery, Penny L., McDonald, Victoria, Florin, Timothy H. and McGuckin, Michael A. (2013) IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells. Gastroenterology, 144 2: 357-368. doi:10.1053/j.gastro.2012.10.043 66   12 Cited 15 times in Scopus15 1
Florin, T. H. (2000). Improvements in serological markers for Crohn's disease and ulcerative colitis. In: DDW Conference Correspondence Project. American Gastroenterology Week DDW, San Diego USA, (2). 1 - 2 May 2000. 52  
Edwards, J., Florin, T. H., Watson, M., Green, A., Newmann, B., Purdy, D. and Radford-Smith, G. L. (1999). Increased family history of colorectal cancer in ulcerative colitis patients. In: Royal Brisbane Hospital Health Care Symposium. Royal Brisbane Hospital Health Care Symposium, Westpac Auditorium Bancroft Cen., QIMR, Brisbane, (61). 21 - 27 Oct, 1999. 46  
Webb, N. A., Khalil, D. and Florin, T. H. (1999). Influence of bacterial niche: 'Plate' antigen is more immunogenic than 'broth' antigen from genetically identical bacteria. In: Journal of Gastroenterology & Hepatology: Abstracts for Australian Gastroenterology Week 1999. Australian Gastroenterology Week 1999, Brisbane, (x-x). 4-8 Oct, 1999. 50  

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