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Bulmer, A.C., Coombes, J.S., Blanchfield, J.T., Toth, I. and Taylor, S.M. (2008). Absorption and pharmacokinetics of bilirubin and biliverdin administration in the rat. In: A. Butt, Proceedings of the Australian Health and Medical Research Congress 2008. Australian Health and Medical Research Congress, Brisbane, (404). 16 - 21 November, 2008. 255  
Michael Morgan, Taylor, Stephen M. and Shiels, I (2007) A C5a receptor antagonist provides greater protection than an NSAID in a skin pouch model of sodium urate induced inflammation. Molecular Immunology, 44 1-3: 217-217. doi:10.1016/j.molimm.2006.07.164 246   0 0
Reid, Robert C., Abbenante, Giovanni, Taylor, Stephen M. and Fairlie, David P. (2003) A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug. Journal of Organic Chemistry, 68 11: 4464-4471. doi:10.1021/jo034228r 234   33 Cited 33 times in Scopus33 0
Woodruff, T. M., Proctor, L. M., Shiels, I. A. and Taylor, S. M. (2004). A cyclic peptide, C5a receptor antagonist analogue confers increased potency in a model of inflammatory bowel disease in rats. In: Molecular immunology: Abstracts of the 20th International Complement Workshop. 20th International Complement Workshop, Honolulu, Hawaii, (326-326). 13-18 June, 2004. doi:10.1016/j.molimm.2004.03.002 280   1 0
Woodruff, T. M., Shiels, I. A., Fairlie, D. and Taylor, S. M. (2001). A new C5a receptor antagonist inhibits monoarticular arthritis in the rat. In: Proceedings of the Complement Associated Diseases, Animal Models and Therapeutics Workshop. Complement Assoc. Diseases, Animal Models & Ther. Workshop, Santorini, Greece, (37-37). 10-14 October, 2001. 78  
Strachan, A. J., Woodruff, T.M., Haaima, G., Fairlie, D. P. and Taylor, S. M. (2000) A new small molecule C5a receptor antagonist inhibits the reverse-passive arthus reaction and endotoxic shock in rats. Journal of Immunology, 164 4: 6560-6565. 118   81
Woodruff, Trent M., Strachan, Anna J., Dryburgh, Nathan, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002) Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat. Arthritis and Rheumatism, 46 9: 2476-2485. doi:10.1002/art.10449 99   75 Cited 73 times in Scopus73 0
Levick, Scott, Loch, David, Rolfe, Barbara, Reid, Robert C., Fairlie, David P., Taylor, Stephan M. and Brown, Lindsay (2006) Antifibrotic activity of an inhibitor of group IIA secretory phospholipase A(2) in young spontaneously hypertensive rats. Journal of Immunology, 176 11: 7000-7007. 124   17 Cited 20 times in Scopus20
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Newman, Michelle L., Ross, Paul A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2005) A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. International Immunopharmacology, 5 5: 883-892. doi:10.1016/j.intimp.2005.01.003 90   21 Cited 26 times in Scopus26 0
Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2003) A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. Journal of Immunology, 171 10: 5514-5520. 96   73 Cited 73 times in Scopus73
Levick, SP, Loch, DC, Taylor, SM and Janicki, JS (2007) Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation. Journal of Immunology, 178 2: 641-646. 117   41 Cited 41 times in Scopus41
Shiels, I. A., Sanderson, S. D. and Taylor, S. M. (1999) Arterially perfused eye model of uveitis. Australian Veterinary Journal, 77 2: 100-104. doi:10.1111/j.1751-0813.1999.tb11677.x 88   6 0
Arumugam, T. V., Shiels, I. A., Strachan, A. J., Abbenante, G., Fairlie, D. P. and Taylor, S. M. (2003) A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats. Kidney International, 63 1: 134-142. doi:10.1046/j.1523-1755.2003.00737.x 116   101 Cited 108 times in Scopus108 0
Mirkovic, S., Seymour, A. M. L., Fenning, A., Strachan, A., Margolin, S. B., Taylor, S. M. and Brown, L. (2002) Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats. British Journal of Pharmacology, 135 4: 961-968. doi:10.1038/sj.bjp.0704539 70   49 Cited 54 times in Scopus54 3
Bulmer, A. C., Coombes, J. S., Blanchfield, J. T., Toth, I., Fassett, R. G. and Taylor, S. M. (2011) Bile pigment phamacokinetics and absorption in the rat: Therapeutic potential for enteral administration. British Journal of Pharmacology, 164 7: 1857-1870. doi:10.1111/j.1476-5381.2011.01413.x 85   15 Cited 15 times in Scopus15 0
Finch, AM, Vogen, SM, Sherman, SA, Kirnarsky, L, Taylor, SM and Sanderson, SD (1997) Biologically active conformer of the effector region of human C5a and modulatory effects of N-terminal receptor binding determinants on activity. Journal of Medicinal Chemistry, 40 6: 877-884. doi:10.1021/jm960727r 75   38 Cited 40 times in Scopus40 0
Woodruff, Trent, Denny, Kerina, Crane, James, Atkin, Julie, Taylor, Steve and Noakes, Peter (2008). Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis. In: Robert Rieben, Molecular Immunology.. ICW Basel, XXII International Complement Workshop, Basel, Switzerland, (4163-4182). 28 September-02 October 2008. doi:10.1016/j.molimm.2008.08.202 162   0 0
Morgan, BP, Griffiths, M, Khanom, H, Taylor, SM and Neal, JW (2004) Blockade of the C5a receptor fails to protect against experimental autoimmune encephalomyelitis in rats. Clinical And Experimental Immunology, 138 3: 430-438. doi:10.1111/j.1365-2249.2004.02646.x 58   20 Cited 22 times in Scopus22 0
Costantini, K. J., Coulthard, L. G. J., Lor, Mary, Woodruff, T. M., Callaway, L. K., Finnell, R. H. and Taylor, S. M. (2010). C5aR protects against folate-deficiency induced neural tube defects in mice. In: Berhane Ghebrehiwet, Ellinor I. Peerschke and Richard R. Kew, Molecular Immunology. Proceedings of: XXIII International Complement Workshop. XXIII International Complement Workshop, New York, NY, U.S.A., (2254-2254). 1-5 August 2010. doi:10.1016/j.molimm.2010.05.169 76   1 0
Li, Rui, Coulthard, Liam G., Wu, M. C. L., Taylor, Stephen M. and Woodruff, Trent M. (2013) C5L2: a controversial receptor of complement anaphylatoxin, C5a. FASEB Journal, 27 3: 855-864. doi:10.1096/fj.12-220509 62   26 Cited 24 times in Scopus24 1
Levick, S., Taylor, S. M., Fairlie, D. and Brown, L. C. (2004). Cardiovascular structural and functional adaptations to group IIAsPLA2 inhibition. In: R. A. Walsh and A. Smisek, XV111 World Congress of the International Society for Heart Research. 2004 ISHR World Congress, Brisbane, Australia, (272-273). 7-11/8/04. 50   0
Shiels, I. A., Taylor, S. M. and Fairlie, D. P. (2000) Cell phenotype as a target of drug therapy in chronic inflammatory diseases. Medical Hypotheses, 54 2: 193-197. doi:10.1054/mehy.1999.0017 57   7 Cited 7 times in Scopus7 0
Higginbottom, Adrian, Cain, Stuart A., Woodruff, Trent M., Proctor, Lavinia M., Madala, Praveen K., Tyndall, Joel D. A., Taylor, Stephen M., Fairlie, David P. and Monk, Peter N. (2005) Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site. Journal of Biological Chemistry, 280 18: 17831-17840. doi:10.1074/jbc.M410797200 110   24 Cited 22 times in Scopus22 0
Proctor, Lavinia M., Arumugam, Thiruma V., Shiels, Ian, Reid, Robert C., Fairlie, David P. and Taylor, Stephen M . (2004) Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury. British Journal of Pharmacology, 142 4: 756-764. doi:10.1038/sj.bjp.0705819 84   43 Cited 50 times in Scopus50 0
Arumugam, Thiruma V., Arnold, Naomi, Proctor, Lavinia M., Newman, Michelle, Reid, Robert C., Hansford, Karl A., Fairlie, David P., Shiels, Ian A. and Taylor, Stephen M. (2003) Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British Journal of Pharmacology, 140 1: 71-80. doi:10.1038/sj.bjp.0705402 94   30 Cited 32 times in Scopus32 0
Brennan, Faith H., Anderson, Aileen J., Taylor, Stephen M., Woodruff, Trent M. and Ruitenberg, Marc J. (2012) Complement activation in the injured central nervous system: Another dual-edged sword?. Journal of Neuroinflammation, 9 1: . doi:10.1186/1742-2094-9-137 61   27 Cited 25 times in Scopus25 2
Manthey, Helga D., Thomas, Anita C., Shiels, Ian A., Zernecke, Alma, Woodruff, Trent M., Rolfe, Barbara and Taylor, Stephen M. (2011) Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice. FASEB Journal, 25 7: 2447-2455. doi:10.1096/fj.10-174284 68   27 Cited 27 times in Scopus27 0
Harkin, Denis W., Romaschin, Alex, Taylor, Stephen M., Rubin, Barry B. and Lindsay, Thomas F. (2004) Complement C5a receptor antagonist attenuates multiple organ injury in a model of ruptured abdominal aortic aneurysm. Journal of Vascular Surgery, 39 1: 196-206. doi:10.1016/j.jvs.2003.07.001 57   29 Cited 36 times in Scopus36 0
Lappas, Martha, Woodruff, Trent M., Taylor, Stephen M. and Permezel, Michael (2012) Complement C5a regulates prolabor mediators in human placenta. Biology of Reproduction, 86 6: 190.1-190.9. doi:10.1095/biolreprod.111.098475 32   3 Cited 6 times in Scopus6 1
Manthey, Helga D., Woodruff, Trent M., Taylor, Stephen M. and Monk, Peter N. (2009) Complement component 5a (C5a). International Journal of Biochemistry and Cell Biology, 41 11: 2114-2117. doi:10.1016/j.biocel.2009.04.005 93   50 Cited 51 times in Scopus51 3
Coulthard, L. G. J., Costantini, K. J., Lor, Mary, Simmons, D., Taylor, S. M. and Woodruff, T. M. (2010). Complement expression in mice throughout neural tube closure. In: Berhane Ghebrehiwet, Ellinor I. Peerschke and Richard R. Kew, Molecular Immunology. Proceedings of: XXIII International Complement Workshop. XXIII International Complement Workshop, New York, NY, U.S.A., (2251-2251). 1-5 August 2010. doi:10.1016/j.molimm.2010.05.163 56   2 0
Woodruff, T.M., Proctor, L.M., Strachan, A.J. and Taylor, S.M. (2006) Complement factor 5a as a therapeutic target. Drugs of The Future, 31 4: 325-334. doi:10.1358/dof.2006.031.04.980656 83   7 Cited 7 times in Scopus7 0
Proctor, Lavinia M., Moore, Tyson A., Monk, Peter N., Sanderson, Sam D., Taylor, Stephen M. and Woodruff, Trent M. (2009) Complement factors C3a and C5a have distinct hemodynamic effects in the rat. International Immunopharmacology, 9 6: 800-806. doi:10.1016/j.intimp.2009.03.002 84   8 Cited 9 times in Scopus9 0
Proctor, Lavinia M., Strachan, Anna J., Woodruff, Trent M., Mahadevan, Indumathy B., Williams, H. Ming, Shiels, Ian A. and Taylor, Stephen M. (2006) Complement inhibitors selectively attenuate injury following administration of cobra venom factor to rats. International Immunopharmacology, 6 8: 1224-1232. doi:10.1016/j.intimp.2006.03.002 343   17 Cited 21 times in Scopus21 0
Denny, Kerina J., Woodruff, Trent M., Taylor, Stephen M. and Callaway, Leonie K. (2013) Complement in pregnancy: a delicate balance. American Journal of Reproductive Immunology, 69 1: 3-11. doi:10.1111/aji.12000 55   9 Cited 11 times in Scopus11 0
Arumugam, Thiruma V., Magnus, Tim, Woodruff, Trent M., Proctor, Lavinia M., Shiels, Ian A., Taylor, Stephen M., A. H. Wu and J. Delanghe (2006) Complement mediators in ischemia-reperfusion injury. Clinica Chimica Acta, 374 1-2: 33-45. doi:10.1016/j.cca.2006.06.010 68   60 Cited 64 times in Scopus64 0
Wong, AK, Finch, AM, Pierens, GK, Taylor, SM and Fairlie, DP (1997) Conformationally constrained small molecule antagonists of C5a.. Abstracts of Papers of The American Chemical Society, 214 9-MEDI. 50   0
Fairlie, David, Taylor, Stephen Maxwell, Finch, Angela Monique and Wong, Allan (1999). Cyclic agonists and antagonists of c5a receptors and g protein-coupled receptors. WO/1999/000406. 136  
Brennan, Faith H., Blomster, Linda V., Costantini, Alexander M., Taylor, Stephen M., Woodruff, Trent M. and Ruitenberg, Marc J. (2012). Deficiency of the complement anaphylatoxin receptor C3aR on leukocytes worsens the outcome from spinal cord injury by promoting neutrophilia. In: Proceedings of the 11th International Congress of Neuroimmunology (ISNI). 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, (89-90). 4-8 November 2012. 70   0
Kotiw, Michael, Morgan, Michael, Taylor, Stephen M. and Shiels, Ian A. (2009) Detection of anti-TNFα activity in canine hyperimmune serum using a TNFα inhibition assay. Veterinary Clinical Pathology, 39 1: 46-52. doi:10.1111/j.1939-165X.2009.00166.x 58   1 Cited 1 times in Scopus1 0
Wong, A., Taylor, S. M. and Fairlie, D. (1999) Development of C5a receptor antagonists. Investigational Drugs, 2 7: 686-693. 54  
Taylor, SM, Sherman, SA, Kirnarsky, L and Sanderson, SD (2001) Development of response-selective agonists of human C5a anaphylatoxin: Conformational, biological, and therapeutic considerations. Current Medicinal Chemistry, 8 6: 675-684. 72   25
Vogen, SM, Paczkowski, NJ, Kirnarsky, L, Short, A, Whitmore, JB, Sherman, SA, Taylor, SM and Sanderson, SD (2001) Differential activities of decapeptide agonists of human C5a: the conformational effects of backbone N-methylation. International Immunopharmacology, 1 12: 2151-2162. doi:10.1016/S1567-5769(01)00141-2 34   12 Cited 19 times in Scopus19 0
Denny, K. J., Crane, J. W., Taylor, S. M. and Noakes, P. G. (2006). Differential localization and expression of complement in a rat model of motor neuron disease. In: ComBio2006, Brisbane Convention & Exhibition Centre, Brisbane, Qld, Aust, (). 24-28 September 2006. 65 44
Taylor, S. M. and Fairlie, D. (2005). Discovery of Potent Cyclic Antagonists of Human C5a Receptors. In I. Morikis and J Lambris (Ed.), Structural Biology of the Complement System (pp. 341-362) New York: CRC Press, Taylor and Francis. 46  
Manthey, H., Taylor, S., Shiels, I. and Rolfe, B. (2007). Does C5a have a role in the pathophysiology of atherosclerosis?. In: W.-C. Song and X.-M. Gao, Molecular Immunology: Proceedings XXI International Complement Workshop. XXI International Complement Workshop, Beijing, China, (213-213). 22-26 October 2006. doi:10.1016/j.molimm.2006.07.154 125   0 0
Proctor, L.M., Woodruff, T.M., Pazckowski, N.P., Monk, P.N. and Taylor, S.M. (2004). Dual C3a/C5a receptor agonism by a C5a C-terminal analogue decapeptide. In: Molecular Immunology: Abstracts of the 20th International Complement Workshop. 20th International Complement Workshop, Honolulu, Hawaii, (297-297). 13-18 June, 2004. doi:10.1016/j.molimm.2004.03.002 98   0 0
Woodruff, T. M., Lee, J. D., Taylor, S. M. and Noakes, P. G. (2010). Dysregulation of the complement system in neurodegenerative disease. In: Berhane Ghebrehiwet, Ellinor I. Peerschke and Richard R. Kew, Molecular Immunology. Proceedings of: XXIII International Complement Workshop. XXIII International Complement Workshop, New York, NY, U.S.A., (2270-2270). 1-5 August 2010. doi:10.1016/j.molimm.2010.05.215 66   0 0
Short, Anna, Wong, Allan K., Finch, Angela M., Haaima, Gerald, Shiels, Ian A., Fairlie, David P. and Taylor, Stephen M. (1999) Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat. British Journal of Pharmacology, 126 2: 551-554. doi:10.1038/sj.bjp.0702338 46   51 Cited 56 times in Scopus56 0
Thundyil, John, Tang, Sung-Chun, Okun, Eitan, Shah, Kausik, Karamyan, Vardan T., Li , Yu-I, Woodruff, Trent M., Taylor, Stephen M., Jo, Dong-Gyu, Mattson, Mark P and Arumugam, Thiruma V. (2010) Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death. Experimental and Translational Stroke Medicine, 2 1: 15-1-15-8. doi:10.1186/2040-7378-2-15 56   Cited 17 times in Scopus17 0

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