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Duggleby, R.G., McCourt, J. A. and Guddat, L. W. (2005). 3D structure of the overlapping sulfonylurea and imidazolinone herbicide binding sites in acetohydroxyacid synthase. In: 9th Int Congress on Amino Acids & Proteins. 9th Int Congress on Amino Acids & Proteins, Vienna, (Abstract). 8-12 Aug, 2005. 164  
Duggleby, R. G. and Pang, S. S. (2000) Acetohydroxyacid Synthase. Journal of Biochemistry & Molecular Biology, 33 1: 1-36. 179   203
McCourt, J. A. and Duggleby, R. G. (2006) Acetohydroxyacid synthase and its role in the biosynthetic pathway for branched-chain amino acids. Amino Acids, 31 2: 173-210. doi:10.1007/s00726-005-0297-3 97   86 Cited 91 times in Scopus91 0
Reboutier, David, Frankart, Cecile, Vedel, Regine, Brault, Mathias, Duggleby, Ronald G., Rona, Jean Pierre, Barny, Marie Anne and Bouteau, Francois (2005) A CFTR chloride channel activator prevents HrpN(ea)-induced cell death in Arabidopsis thaliana suspension cells. Plant Physiology and Biochemistry, 43 6: 567-572. doi:10.1016/j.plaphy.2005.03.003 144   13 Cited 15 times in Scopus15 0
Barnett, Amanda C., Tsvetanov, Sergey, Gamage, Niranjali, Martin, Jennifer L., Duggleby, Ronald G. and McManus, Michael E. (2004) Active site mutations and substrate inhibition in human sulfotransferase 1A1 and 1A3. The Journal of Biological Chemistry, 279 18: 18799-18805. doi:10.1074/jbc.M312253200 117   29 Cited 32 times in Scopus32 0
Lee, H., Hwang, J., Duggleby, R. G., Winzor, D. J., Smith, R. W. and Kroon, P. A. (2000). A high affinity calcium binding site determines the folding efficiency of a ligand-binding modul of the human low density lipoprotein receptor. In: ComBio 2000 : combined conference abstracts : 44th Annual ASBMB, 40th Annual ASPP, Annual NZSBMB, 22nd Annual NZSPP. Combio 2000, Wellington, New Zealand, (1-58). 11-14 December, 2000. 63  
Brix, Lulu A., Barnett, Amanda C., Duggleby, Ronald G., Leggett, Barbara and McManus, Michael E. (1999) Analysis of the substrate specificity of human sulfotransferases SULT1A1 and SULT1A3: Site-directed mutagenesis and kinetic studies. Biochemistry, 38 32: 10474-10479. doi:10.1021/bi990795q 91   43 Cited 47 times in Scopus47 0
Tyagi, R., Lai, R. Y. and Duggleby, R.G. (2004) A new approach to 'megaprimer' polymerase chain reaction mutagenesis without an intermediate gel purification step. BMC Biotechnology, 4 2: 1-6. doi:10.1186/1472-6750-4-2 65   36 Cited 41 times in Scopus41 0
Chang, A. K., Duggleby, R. G. and Nixon, P. F. (1999). A study of the role of the C-terminal helix of Zymomonas mobilis pyruvate decarboxylase. In: Enzyme Structure and Function - A Satellite Conference of the Australian Society for Biochemistry and Molecular Biology. Enzyme Strucutre and Function, Fraser Island, (9a). 22-25 September, 1999. 33  
Yago, J. M., Garcia-Sevilla, F., Garrudi-del Solo, C., Duggleby, R G and Varon, R. (2006) A windows program for the derivation of steady-state equations in enzyme systems. Applied Mathematics And Computation, 181 -: 837-852. doi:10.1016/j.amc.2006.02.016 185   6 Cited 7 times in Scopus7 0
Wu, YG, Chen, WY, Zhang, ZW, Yang, GZ, Li, W and Duggleby, RG (2003) Biochemical characterization of two mutants of human pyruvate dehydrogenase, F205L and T231A of the E1 alpha subunit. Journal of Inherited Metabolic Disease, 26 7: 671-674. doi:10.1023/B:BOLI.0000005628.16515.01 44   0 Cited 1 times in Scopus1 0
Christie, M. and Duggleby, R.G. (2005). Cloning, purification and characterization of ketol acid reductoisomerase of yeast. In: East Coast Protein Meeting. East Coast Protein Meeting, Coffs Harbour, (Abstract). 24-26 June, 2005. 59  
Wu, Y. G., Widjaja, S. L., Huang, C. Y., Li, W., Nixon, P. F. and Duggleby, R. G. (2001) Congenital lactic acidosis: Evaluation of the properties of the A199T natural variant of human pyruvate dehydrogenase E1 alpha by in vitro mutation. Molecular Genetics And Metabolism, 72 3: 269-272. doi:10.1006/mgme.2000.3137 58   2 Cited 2 times in Scopus2 0
Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2004) Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl. Acta Crystallographica Section D-biological Crystallography, 60 153-155. doi:10.1107/S0907444903025423 46   22 Cited 21 times in Scopus21 0
Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2001). Crystallization of the catalytic subunit of Saccharomyces cerevisiae acetohydroxyacid synthase. In: Acta crystallographica. Section D, Biological crystallography: Papers presented at COMBIO 2001. COMBIO 2001, Canberra, ACT, Australia, (1321-1323). 1-4 October, 2001. doi:10.1107/S0907444901011635 51   22 Cited 23 times in Scopus23 0
Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2001) Crystallization of the catalytic subunit of Saccharomyces cerevisiae acetohydroyacid synthase. Acta Crystallographica Section D, D57 1321-1323. 33  
Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2002) Crystallization of the FAD-independent acetolactate synthase of Klebsiella pneumoniae. Acta Crystallographica Section D - Biological Crystallography, D58 1237-1239. doi:10.1107/S0907444902008132 66   7 Cited 7 times in Scopus7 0
Duggleby, R.G., Tyagi, R., Duquerroy, S., Navaza, J. and Guddat, L. W. (2005). Crystal structure of Escherichia coli ketol-acid reductoisomerase. In: East Coast Protein Meeting. East Coast Protein Meeting, Coffs Harbour, (Abstract). 24-26 June, 2005. 42  
Pang, S. S., Duggleby, R. G. and Guddat, L. W. (2002) Crystal structure of yeast acetohydroxyacid synthase: A target for herbicidal inhibitors. Journal of Molecular Biology, 317 2: 249-262. doi:10.1006/jmbi.2001.5419 65   139 Cited 138 times in Scopus138 0
Wang, Jian-Guo, Lee, Patrick K.-M., Dong, Yu-Hui, Pang, Siew Siew, Duggleby, Ronald G., Li, Zheng-Ming and Guddat, Luke W. (2009) Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. FEBS Journal, 276 5: 1282-1290. doi:10.1111/j.1742-4658.2009.06863.x 95   22 Cited 23 times in Scopus23 0
Lee, YT, Ta, HT and Duggleby, RG (2005) Cyclopropane-1,1-dicarboxylate is a slow-, tight-binding inhibitor of rice ketol-acid reductoisomerase. Plant Science, 168 4: 1035-1040. doi:10.1016/j.plantsci.2004.11.020 46   32 Cited 31 times in Scopus31 0
Lee, Yu-ting, Ta, Hang T. and Duggleby, Ronald G. (2005) Cyclopropane-1,1-dicarboxylate is a slow-, tight-binding inhibitor of rice ketol-acid reductoisomerase. Plant Science, 168 4: 1035-1040. doi:10.1016/j.plantsci.2004.11.020 15   32 Cited 31 times in Scopus31 0
Duggleby, RG (2006) Domain relationships in thiamine diphosphate-dependent enzymes. Accounts of Chemical Research, 39 8: 550-557. doi:10.1021/ar068022z 28   46 Cited 45 times in Scopus45 0
Lee, Yu-Ting, Chang, Alan K. and Duggleby, Ronald G. (1999) Effect of mutagenesis at serine 653 of Arabidopsis thaliana acetohydroxyacid synthase on the sensitivity to imidazolinone and sulfonylurea herbicides.. FEBS Letters, 452 3: 341-345. doi:10.1016/S0014-5793(99)00668-7 45   43 Cited 43 times in Scopus43 0
Huang, C-Y., Nixon, P. F. and Duggleby, R.G. (1999) Effect of Mutagenesis of V111 and L112 on the Substrate Specificity of Zymomonas mobilis Pyruvate Decarboxylase. Journal of Biochemistry and Molecular Biology, 32 1: 39-44. 119   2
Tittmann, Kai, Schroder, Kathrin, Golbik, Ralph, McCcourt, Jennifer, Kaplun, Alexander, Duggleby, Ronald G., Barak, Ze'ev, Chipman, David M. and Hubner, Gerhard (2004) Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzyme. Biochemistry, 43 27: 8652-8661. doi:10.1021/bi049897t 77   26 Cited 27 times in Scopus27 0
McCourt, J. A., Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2005) Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. Biochemistry, 44 7: 2330-2338. doi:10.1021/bi047980a 65   70 Cited 73 times in Scopus73 0
McCourt, J. A., Pang, S. S., King-Scott, J., Guddat, L. W. and Duggleby, R.G. (2005). Elucidation of the binding site for five sulfonylurea herbicides in Arabidopsis thaliana. In: 30th Annual Lorne Conference on Protein Structure and Function. 30th Annual Lorne Conference on Protein Structure and Function, Lorne, (Abstract). 6-11 Feb, 2005. 229  
Dumas, Renaud, Biou, Valérie, Halgand, Frédéric, Douce, Roland and Duggleby, Ronald G. (2001) Enzymology, structure, and dynamics of acetohydroxy acid isomeroreductase. Accounts of Chemical Research, 34 5: 399-408. doi:10.1021/ar000082w 50   52 Cited 53 times in Scopus53 0
Duggleby, R. G., Kartikasari, A. E. R., Wunsch, R. M., Lee, Y. T., Kil, M. W., Shin, J. Y. and Chang, S. I. (2000) Expression in Escherichia coli of a putative human acetohydroxyacid synthase. Journal of Biochemistry & Molecular Biology, 33 3: 195-201. 71   3
Pang, S. S. and Duggleby, R. G. (1999). Expression, purification, characterisation and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase. In: Combined Conference Abstracts: 43rd Annual ASBMB, 18th Annual ANZSCDB and 39th Annual ASPP. ComBio 99, Conrad Jupiters, Gold Coast, (Pos-Wed-71). 27-30 September, 1999. 32  
Pang, S. S. and Duggleby, R. G. (1999). Expression, purification, characterisation, and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase. In: Enzyme Structure and Function - A Satellite Conference of the Australian Society for Biochemistry and Molecular Biology. Enzyme Structure and Function, Fraser Island, (2b). 22-25 September, 1999. 35  
Pang, S. S. and Duggleby, R.G. (2000). Expression, purification, characterization and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase. In: 18th International Congress for Biochemistry and Molecular Biology. , Birmingham, England, (454). 16-20 July, 2000. 54  
Pang, Siew Siew and Duggleby, Ronald G. (1999) Expression, purification, characterization and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase. Biochemistry, 38 16: 5222-5231. doi:10.1021/bi983013m 47   52 Cited 62 times in Scopus62 0
McCourt, J. A., Tyagi, R., Guddat, L. W., Biou, V. and Duggleby, R. G. (2004) Facile crystallization of Escherichia coli ketol-acid reductoisomerase. Acta Crystallographica Section D-biological Crystallography, 60 1432-1434. doi:10.1107/S0907444904012247 81   3 Cited 3 times in Scopus3 0
McCourt, J. A. and Duggleby, R.G. (2003). Herbicidal inhibition of Escherichia coli acetohydroxy acid synthase II: An investigation into the process of inactivation. In: East Coast Protein Meeting 2003. East Coast Protein Meeting, Coffs Harbour, ((Abstract)). 27-29 June, 2003. 30  
McCourt, J. A., Pang, S. S., King-Scott, J., Guddat, L. W. and Duggleby, R. G. (2006) Herbicide-binding Sites Revealed in the Structure of Plant Acetohydroxyacid Synthase. Proceedings of The National Academy of Sciences of The United States of America, 103 3: 569-573. doi:10.1073/pnas.0508701103 74   130 Cited 135 times in Scopus135 3
McCourt, J. A. and Duggleby, R. G. (2005) How an enzyme answers. multiple-choice questions. Trends In Biochemical Sciences, 30 5: 222-225. doi:10.1016/j.tibs.2005.03.006 121   6 Cited 7 times in Scopus7 0
Tittman, K., Golbik, R., Uhlemann, K., Hubner, G., Khailova, L., Patel, M., Jordan, F. M., Chipman, D. M., Duggleby, R.G. and Schneider, G. (2004). How thiamine works in enzymes: Time-resolved NMR snapshots of TDP-dependent enzymes in action. In F. Jordan and M. S. Patel (Ed.), Thiamine. Catalytic Mechanisms 1st ed. (pp. 57-76) USA: Marcel Dekker. 116  
Gamage, N., Barnett, A., Hempel, N., Duggleby, R. G., Windmill, K. F., Martin, J. L. and McManus, M. E. (2006) Human sulfotransferases and their role in chemical metabolism. Toxicological Sciences, 90 1: 5-22. doi:10.1093/toxsci/kfj061 72   193 Cited 205 times in Scopus205 0
Hempel, N., Barnett, A., Gamage, N., Duggleby, R.G., Windmill, K. F., Martin, J. L. and McManus, M. E. (2005). Human SULT1A SULTs. In Pacifici, Gian Maria and Coughtrie, Michael W. H. (Ed.), Human Cytosolic Sulfotransferases 1 ed. (pp. 179-230) Boca Raton, FL, USA: Taylor & Francis Group, LLC (CRC Press). 124  
Lee, Y. T. and Duggleby, R. G. (2001) Identification of the regulatory subunit of Arabidopsis thaliana acetohydroxyacid synthase and reconstitution with its catalytic subunit. Biochemistry, 40 23: 6836-6844. doi:10.1021/bi002775q 38   44 Cited 46 times in Scopus46 0
Chipman, D. M., Duggleby, R. G. and Tittmann, K. (2005) Mechanisms of acetohydroxyacid synthases. Current Opinion In Chemical Biology, 9 5: 475-481. doi:10.1016/j.cbpa.2005.07.002 30   49 Cited 50 times in Scopus50 0
Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2003). Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. In: East Coast Protein Meeting 2003. East Coast Protein Meeting, Coffs Harbour, (Poster). 27-29 June, 2003. 38  
Pang, S. S., Guddat, L. W. and Duggleby, R. G. (2003) Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. Journal of Biological Chemistry, 278 9: 7639-7644. doi:10.1074/jbc.M211648200 149   121 Cited 120 times in Scopus120 0
Wu, Y-G., Chang, A. K., Nixon, P. F., Li, W. and Duggleby, R. G. (2000) Mutagenesis at Asp-27 of pyruvate decarboxylase from Zymomonas mobilis: Effect on its ability to form acetoin and acetolactate. European Journal of Biochemistry, 267 21: 6493-6500. doi:10.1046/j.1432-1327.2000.01744.x 108   11 Cited 13 times in Scopus13 0
Lee, Y. L. and Duggleby, R. G. (2000) Mutagenesis studies of the sensitivity of Escherichia coli acethydroxyacid synthase II to herbicides and valine. Biochemical Journal, 350 1: 69-73. doi:10.1042/0264-6021:3500069 28   14 Cited 16 times in Scopus16 0
Pham, S. and Duggleby, R.G. (2003). Mutants of yeast acetohydroxyacid synthase with altered regulation by valine and MGATP. In: East Coast Protein Meeting 2003. East Coast Protein Meeting 2003, Coffs Harbour, (Poster). 27-29 June, 2003. 20  
Lee, Y. T. and Duggleby, R. G. (2006) Mutations in the regulatory subunit of yeast acetohydroxyacid synthase affect its activation by MgATP. Biochemical Journal, 395 2: 331-336. doi:10.1042/BJ20051793 28   6 Cited 8 times in Scopus8 0
Tittmann, K., Golbik, R., Uhlemann, K., Khailova, L., Schneider, G., Patel, M., Jordan, F., Chipman, D. M., Duggleby, R. G. and Hubner, G. (2003) NMR analysis of covalent intermediates in thiamin diphosphate enzymes. Biochemistry, 42 26: 7885-7891. doi:10.1021/bi034465o 81   99 Cited 104 times in Scopus104 1

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