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Lacomblez, L, Bensimon, G, Leigh, PN, Guillet, P, Powe, L, Durrleman, S, Delumeau, JC, Meininger, V, Puech, AJ, Whitehead, J, Asselain, B, Cesaro, P, Larrey, D, Rossor, M, Zimmerman, HJ, Salzman, P, Doppler, V, Lloyd, CM, Maloteaux, JM, Delwaide, C, Laterre, EC, Bouchard, JP, Duquette, P, Girard, M, Masse, C, Eisen, A, Blin, O, Azulay, JP, BilleTurc, F, Pouget, J, Bouche, P, Camu, M, Carlander, B, Billiard, M, Clanet, M, Angibaud, G, ArneBes, MC, Benazet, M, Couratier, P, Vallat, JM, Desnuelle, C, Lagueny, A, Ellie, E, Dib, M, Rozier, A, Salachas, F, Viader, F, Delaunay, D, Dengler, R, Kuther, G, Troger, M, Ludolph, A, Bachus, R, Gericke, C, Przuntek, H, Langkafel, M, Schimrigk, K, Jost, WH, Osterhage, J, Prudlo, J, Mora, J, Chaverri, D, Saenz, E, Jefferson, D, Orpe, V, Lane, RJM, Orrell, RW, Barbie, T, Mitchell, JD, Kilshaw, J, Pall, HS, Goodwin, M, Schady, W, Duncan, S, Moore, C, Richards, C, Shaw, PJ, Chari, G, Pickering, B, Swash, M, Harati, Y, Gooch, CL, Echols, CW, Miller, RG, Gelinas, DF, Quien, A, Munstat, TL, Thornell, B, Rothstein, JD, Clawson, L, Sufit, R, Casey, P, Delumeau, J, Truffinet, P, Debove, C, Enfrin, P, Hampton, G, Muller, F, Nguyen, T, Rothfuss, D, Senechal, A, Shu, C, Leswell, P, Whitworth, P, DeBoe, M, DeBruyckere, M, Fisher, W, Konig, M, Verdugo, L, delosTerreros, MS, Deakin, D, Giguere, M, Adair, K, Franco, M, Skarinsky, D, Wexler, M, Pizzato, M, Ledoux, L, Campagnes, E, Hartnett, M, Bastien, P, Bejuit, R, Kim, Y, LeLann, L, Leroy, F, Papillon, C and OrvoenFrija, E (1996) A confirmatory dose-ranging study of riluzole in ALS. Neurology, 47 6: S242-S250. 19   66
Whitehead, J. P., Richards, A. A., Hickman, I. J., Macdonald , G. A. and Prins, J. B. (2006) Adiponectin – a key adipokine in the metabolic syndrome. Diabetes, Obesity and Metabolism, 8 3: 264-280. doi:10.1111/j.1463-1326.2005.00510.x 92   276 Cited 313 times in Scopus313 0
Verkest, Kurt R., Fleeman, Linda M., Morton, John M., Rand, Jacquie S., Rose, Felicity J., Richards, Ayanthi A., Whitehead, Jonathan P. and Ishioka, Katsumi (2008). Adiponectin concentration does not correlate with obesity-associated changes in fasting insulin sensitivity in dogs. In: Journal of Veterinary Internal Medicine. Proceedings of: 26th Annual ACVIM Forum. 26th Annual ACVIM Forum, San Antonio, TX., U.S.A., (791-792). 4–7 June 2008. doi:10.1111/j.1939-1676.2008.0103.x 191   0 0
Simpson, Fiona and Whitehead, Jonathan P. (2010) Adiponectin-It's all about the modifications. International Journal of Biochemistry & Cell Biology, 42 6: 785-788. doi:10.1016/j.biocel.2009.12.021 63   31 Cited 43 times in Scopus43 0
Richards, Ayanthi A., Stephens, Tim, Charlton, Hayley K., Jones, Alun, Macdonald, Graeme A., Prins, Johannes B. and Whitehead, Jonathan P. (2006) Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: Evidence for regulation of multimerization by alterations in posttranslational modifications. Molecular Endocrinology, 20 7: 1673-1687. doi:10.1210/me.2005-0390 257   97 Cited 111 times in Scopus111 0
Tan, Heok Yit, Rand, Jacquie S., Morton, John M., Fleeman, Linda M., Armstrong, P. Jane, Coradini, Marcia, Ishioka, Katsumi, Verkest, Kurt R., Richards, Ayanthi A., Rawlings, John M., Rose, Felicity J. and Whitehead, Jonathan P. (2011) Adiponectin profiles are affected by chronic and acute changes in carbohydrate intake in healthy cats. General and Comparative Endocrinology, 172 3: 468-474. doi:10.1016/j.ygcen.2011.04.012 65   10 Cited 11 times in Scopus11 0
Russell, Anthony W., McIntyre, H. David, Whitehead, Jon P. and Prins, Johannes B. (2005) Adipose tissue from pregnant women with and without gestational diabetes mellitus: Insulin-sensitive but resistant to hyperosmolarity. American Journal of Obstetrics and Gynecology, 193 6: 2017-2023. doi:10.1016/j.ajog.2005.04.058 154   2 Cited 1 times in Scopus1 0
Verkest, K.R., Rose, F.J., Fleeman, L.M., Rand, J.S., Morton, J.M., Richards, A.A., Ishioka, K. and Whitehead, J.P. (2011) Adiposity and adiponectin in dogs: investigation of causes of discrepant results between two studies. Domestic Animal Endocrinology, 41 1: 35-41. doi:10.1016/j.domaniend.2011.03.004 57   5 Cited 7 times in Scopus7 0
Jensen, Jørgen, Gronning-Wang, Line M., Jebens, Einar, Whitehead, Jonathan P., Zorec, Robert and Shepherd, Peter R. (2008) Adrenaline potentiates insulin-stimulated PKB activation in the rat fast-twitch epitrochlearis muscle without affecting IRS-1-associated PI 3-kinase activity. Pflügers Archiv European Journal of Physiology, 456 5: 969-978. doi:10.1007/s00424-008-0471-z 83   8 Cited 9 times in Scopus9 0
Iyer, Abishek, Lim, Junxian, Poudyal, Hemant, Reid, Robert C., Suen, Jacky Y., Webster, Julie, Prins, Johannes B., Whitehead, Jonathan P., Fairlie, David P. and Brown, Lindsay (2012) An inhibitor of phospholipase A2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats. Diabetes, 61 9: 2320-2329. doi:10.2337/db11-1179 83 3 7 Cited 7 times in Scopus7 1
Hickman, Ingrid J., Byrne, Nuala M., Croci, Ilaria, Chachay, Veronique S., Clouston, Andrew D., Hills, Andrew P., Bugianesi, Elisabetta, Whitehead, Jonathan P, Gastaldelli, Amalia, O'Moore-Sullivan, Trisha M., Prins, Johannes B. and Macdonald, Graeme A . (2013) A Pilot Randomised Study of the Metabolic and Histological Effects of Exercise in Non-alcoholic Steatohepatitis. Journal of Diabetes and Metabolism, 4 8: . doi:10.4172/2155-6156.1000300 58   0
Hutley, Louise J., Newell, Felicity S., Kim, Yu-Hee, Luo, Xiao, Widberg, Charlotte H., Shurety, Wenda, Prins, Johannes B. and Whitehead, Jonathan P. (2011) A putative role for endogenous FGF-2 in FGF-1 mediated differentiation of human preadipocytes. Molecular and Cellular Endocrinology, 339 1-2: 165-171. doi:10.1016/j.mce.2011.04.012 60   5 Cited 5 times in Scopus5 0
Nugent, C., Prins, J. B., Whitehead, J. P., Wentworth, J., Chatterjee, V. and Orahilly, S. (2001) Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane: Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor. The Journal of Biological Chemistry, 276 12: 9149-9157. doi:10.1074/jbc.M009817200 168   61 Cited 64 times in Scopus64 0
Campbell, Katrina L., Johnson, David W., Bauer, Judith, Hawley, Carmel M., Isbel, Nicole M., Stowasser, Michael, Whitehead, Jonathan P., Dimeski, Goce and McMahon, Emma (2014) A randomized trial of sodium-restriction on kidney function, fluid volume and adipokines in CKD patients. BMC Nephrology, 15 1: 57.1-57.6. doi:10.1186/1471-2369-15-57 24   1 Cited 1 times in Scopus1 3
Hughes, T. E., Kim, D. D., Marjason, J., Proietto, J., Whitehead, J. P. and Vath, J. E. (2013) Ascending dose-controlled trial of beloranib, a novel obesity treatment for safety, tolerability, and weight loss in obese women. Obesity, 21 9: 1782-1788. doi:10.1002/oby.20356 21   8 Cited 9 times in Scopus9 19
Tan, H. Y., Rand, J. S., Morton, J. M., Fleeman, L. M., Coradini, M., Armstrong, P. J., Verkest, K. R., Ishioka, K., Rose, F., Richards, A., Rawlings, J. M. and Whitehead, J. P. (2008). Association of adiponectin multimers with dietary nutrient composition, body weight gain, meal feeding, and insulin sensitivity in cats. In: Journal of Veterinary Internal Medicine. 26th Annual American College of Veterinary Internal Medicine Forum, San Antonio, USA, (792-793). 4-7 June 2008. doi:10.1111/j.1939-1676.2008.0103.x 95   0 0
Ngo, Sherry, Barry, Janelle, Prins, John and Whitehead, Jon (2008). BS5-3 Dexamethasone inhibits insulin stimulated glucose uptake by reducing akt substrate of 160 kDa (AS160) phosphorylation in human adipocytes. In: N. Hotta, Diabetes Research and Clinical Practice: Abstracts of the 7th International Diabetes Federation Western Pacific Region Congress. 7th International Diabetes Federation Western Pacific Region Congress, Wellington, New Zealand, (S19-S19). 31 March - 04 April 2008. doi:10.1016/S0168-8227(08)70695-8 103   0 0
Rau, H, Whitehead, JP, Reaves, BJ and O'Rahilly, S (1998). Cell biological characterization of a truncated human leptin (frameshift 133). In: Diabetologia. , , (A64-A64). . 1   0
Winzer, Brooke M., Reeves, Marina M., Paratz, Jennifer, Whitehead, Jon and Whiteman, David C. (2012). Changes in adiposity, gastro-oesophageal reflux and obesity-related hormones following a 24-week exercise intervention in men with Barrett'S Oesophagus. In: Abstracts of the Joint Meeting of the COSA 39th Annual Scientific Meeting and IPOS 14th World Congress of Psycho–Oncology. The Joint Meeting of the COSA 39th Annual Scientific Meeting and IPOS 14th World Congress of Psycho–Oncology, Brisbane Australia, (314-314). 13-15 November 2012. doi:10.1111/ajco.12030 51   0 0
Gunter, Jennifer H., Thomas, Elaine c., Lengefeld, Nadia, Kruger, Sarah J., Worton, Leah, Gardiner, Edith M., Jones, Alun, Barnett, Nigel L. and Whitehead, Jonathan P. (2008) Characterisation of inosine monophosphate dehydrogenase expression during retinal development: Differences between variants and isoforms. International Journal of Biochemistry & Cell Biology, 40 9: 1716-1728. doi:10.1016/j.biocel.2007.12.018 69   12 Cited 13 times in Scopus13 0
Keshvari, Sahar, Rose, Felicity J., Charlton, Hayley K., Scheiber, Nicole L., Webster, Julie, Kim, Yu-Hee, Choaping Ng, Parton, Robert G. and Whitehead, Jonathan P. (2013) Characterisation of the adiponectin receptors: The non-conserved N-terminal region of AdipoR2 prevents its expression at the cell-surface. Biochemical and Biophysical Research Communications, 432 1: 28-33. doi:10.1016/j.bbrc.2013.01.092 67   2 Cited 2 times in Scopus2 0
Newell, Felicity S., Su, Hua, Tornqvist, Hans, Whitehead, Jonathan P., Prins, Johannes B. and Hutley, Louise J. (2006) Characterization of the transcriptional and functional effects of fibroblast growth factor-1 on human preadipocyte differentiation. The FASEB Journal, 20 14: 2615-2617. doi:10.1096/fj.05-5710fje 56   33 Cited 22 times in Scopus22 0
Montague, CT, Farooqi, IS, Whitehead, JP, Soos, MA, Rau, H, Wareham, NJ, Sewter, CP, Digby, JE, Mohammed, SN, Hurst, JA, Cheetham, CH, Earley, AR, Barnett, AH, Prins, JB and ORahilly, S (1997) Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature, 387 6636: 903-908. 29   1658
Whitehead, JP, Soos, MA, Aslesen, R, O'Rahilly, S and Jensen, J (2000) Contraction inhibits insulin-stimulated insulin receptor substrate-1/2-associated phosphoinositide 3-kinase activity, but not protein kinase B activation or glucose uptake, in rat muscle. Biochemical Journal, 349 775-781. 2   27
Yu, Xing Xian, Watts, Lynnetta M., Hutley, Louise, Whitehead, Jon, Prins, John, Wacher, Vince, Monia, Brett P. and Bhanot, Sanjay (2008). Decreased adiposity and improved insulin sensitivity in obese mice after suppression of hepatic and adipose tissue FGFR4 expression. In: Diabetes. 67th Annual Meeting of the American-Diabetes-Association, San Francicso Ca, (A475-A475). Jun 06-10, 2008. 12   0
Digby, V. E., Crowley, V., Sewter, C., Whitehead, J. P., Prins, J. and Orahilly, S. (2000) Depot-related and thiazolidinedione-responsive expression of uncoupling protein 2 (UCP2) in human adipocytes. International Journal of Obesity, 24 5: 585-592. doi:10.1038/sj.ijo.0801201 57   23 Cited 23 times in Scopus23 0
Sanchez, W. Y., McGee, S. L., Connor, T., Mottram, B., Wilkinson, A., Whitehead, J. P., Vuckovic, S. and Catley, L. (2013) Dichloroacetate inhibits aerobic glycolysis in multiple myeloma cells and increases sensitivity to bortezomib. British Journal of Cancer, 108 8: 1624-1633. doi:10.1038/bjc.2013.120 71   15 Cited 17 times in Scopus17 2
Urso, B, Cope, DL, Kalloo-Hosein, HE, Hayward, AC, Whitehead, JP, O'Rahilly, S and Siddle, K (1999) Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like growth factor receptor in 3T3-L1 adipocytes. Journal of Biological Chemistry, 274 43: 30864-30873. doi:10.1074/jbc.274.43.30864 5   47 Cited 50 times in Scopus50 0
Thomas, Elaine C., Gunter, Jennifer H., Webster, Julie A., Schieber, Nicole L., Oorschot, Viola, Parton, Robert G. and Whitehead, Jonathan P. (2012) Different characteristics and nucleotide binding properties of Inosine Monophosphate Dehydrogenase (IMPDH) isoforms. PloS One, 7 12: e51096.1-e51096.14. doi:10.1371/journal.pone.0051096 65   9 Cited 8 times in Scopus8 0
KallooHosein, HE, Whitehead, JP, Soos, M, Tavare, JM, Siddle, K and ORahilly, S (1997) Differential signaling to glycogen synthesis by the intracellular domain of the insulin versus the insulin-like growth factor-1 receptor. Journal of Biological Chemistry, 272 39: 24325-24332. doi:10.1074/jbc.272.39.24325 8   25 Cited 28 times in Scopus28 0
Verkest, K. R., Rand, J. S., Fleeman, L. M., Morton, J. M., Richards, A. A., Rose, F. J. and Whitehead, J. P. (2011) Distinct adiponectin profiles might contribute to differences in susceptibility to type 2 diabetes in dogs and humans. Domestic Animal Endocrinology, 41 2: 67-73. doi:10.1016/j.domaniend.2011.03.003 39   13 Cited 14 times in Scopus14 0
Worton, L. E., Shi, Y., Smith, E. J., Little, D. G., Whitehead, J. P. and Gardiner, E. M. (2007). Ectoderm neural cortex 1, a Wnt target gene, is expressed in chondrocytic and osteoblastic cells. In: Journal of Bone and Mineral Research. 29th Annual Meeting of the American-Society-for-Bone-and-Mineral-Research, Honolulu Hi, (S245-S245). Sep 16-19, 2007. 4   0
Ruzzin, J, Brennesvik, EO, Ktori, C, Jebens, E, Whitehead, JP, Shepherd, P and Jensen, J (2002). Effects of adrenaline on glucose metabolism and insulin signalling in rat epitrochlearis muscles. In: Diabetologia. 38th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Budapest Hungary, (A196-A196). Sep, 2002. 2   0
Charlton, HK, Webster, J, Kruger, S, Simpson, F, Richards, AA and Whitehead, JP (2010) ERp46 binds to AdipoR1, but not AdipoR2, and modulates adiponectin signalling. Biochemical and Biophysical Research Communications, 392 2: 234-239. doi:10.1016/j.bbrc.2010.01.029 79   31 Cited 33 times in Scopus33 0
Whitehead, JP, Humphreys, PJ, Dib, K, Goding, JW and ORahilly, S (1997) Expression of the putative inhibitor of the insulin receptor tyrosine kinase PC-1 in dermal fibroblasts from patients with syndromes of severe insulin resistance. Clinical Endocrinology, 47 1: 65-70. doi:10.1046/j.1365-2265.1997.2171021.x 1   12 0
Hutley, Louise, Shurety, Wenda, Newell, Felicity, McGeary, Ross P., Pelton, Nicole S., Grant, Jennifer A., Herington, Adrian, Cameron, Donald P., Whitehead, Jon P. and Prins, Johannes B. (2004) Fibroblast growth factor 1: A key regulator of human adipogenesis. Diabetes, 53 12: 3097-3106. doi:10.2337/diabetes.53.12.3097 113   53 Cited 57 times in Scopus57 0
Newell, F. S., Whitehead, J. P., Hutley, L. J. and Prins, J. B. (2005). Fibroblast growth factor-1 (FGF-1) as a potential therapeutic target for obesity: mechanisms of FGF-1 action in human preadipocytes. In: Diabetologia: Abstracts of the 41st Annual Meeting of the European-Association-for-the-Study-of-Diabetes. 41st Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Athens, Greece, (A215-A215). 10-15 September, 2005. doi:10.1007/s00125-005-1909-x 95   0 0
Widberg, C. H., Newell, F. S., Bachmann, A. W., Ramnoruth, S. N., Spelta, M. C., Whitehead, J. P., Hutley, L. J. and Prins, J. B. (2009) Fibroblast growth factor receptor 1 is a key regulator of early adipogenic events in human preadipocytes. American Journal of Physiology Endocrinology and Metabolism, 296 1: E121-E131. doi:10.1152/ajpendo.90602.2008 68   30 Cited 31 times in Scopus31 0
Berger, D., Barroso, I., Soos, M., Yeo, G., Schafer, A. J., O'Rahilly, S. and Whitehead, J. P. (2002) Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1. Diabetic Medicine, 19 10: 804-809. doi:10.1046/j.1464-5491.2002.00779.x 44   7 Cited 9 times in Scopus9 0
Taing, M. W., Rose, F. J. and Whitehead, J. P. (2014) GLP-1(28-36)amide, the glucagon-like peptide-1 metabolite: Friend, foe, or pharmacological folly?. Drug Design, Development and Therapy, 8 677-688. doi:10.2147/DDDT.S35723 24   Cited 1 times in Scopus1 0
Jensen, J, Jebens, E, Brennesvik, EO, Engebretsen, EML and Whitehead, JP (2002). Glucose metabolism and insulin signalling in rat skeletal muscle with altered glycogen levels.. In: Diabetologia. 38th EASD Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Budapest Hungary, (A228-A228). Sep 01-05, 2002. 3   0
Stolic, M., Russell, A., Hutley, L., Fielding, G., Hay, J., MacDonald, G., Whitehead, J. and Prins, J. (2002) Glucose uptake and insulin action in human adipose tissue - influence of BMI, anatomical depot and body fat distribution. International Journal of Obesity, 26 1: 17-23. doi:10.1038/sj.ijo.0801850 175   34 Cited 39 times in Scopus39 0
Russell, A. W., Whitehead, J. P., McIntyre, H. D. and Prins, J. B. (2003). Glucose uptake and insulin-signaling in human adipose tissue in pregnancy. In: Diabetologia: Abstracts of the IDF Congress in Paris 2003. IDF Congress Paris 2003, Paris, France, (A254-A255). 24–29 August, 2003. doi:10.1007/s00125-003-1190-9 193   0 0
Simpson, Fiona, Whitehead, Jonathan P. and James, David E. (2001) GLUT4 - At the cross roads between membrane trafficking and signal transduction. Traffic, 2 1: 2-11. doi:10.1034/j.1600-0854.2001.020102.x 140   76 Cited 78 times in Scopus78 0
Hasnain, Sumaira Z., Borg, Danielle J., Harcourt, Brooke E., Tong, Hui, Sheng, Yonghua H., Ng, Choa Ping, Das, Indrajit, Wang, Ran, Chen, Alice C.-H., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathan P., Forbes, Josephine M., Prins, Johannes B. and McGuckin, Michael A. (2014) Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nature Medicine, 20 12: 1417-1426. doi:10.1038/nm.3705 27   2 Cited 1 times in Scopus1 70
Wang, Amy Y-H., Hickman, Ingrid J., Richards, Ayanthi A., Whitehead, Jonathan P., Prins, Johannes B. and Macdonald, Graeme A. (2005) High molecular weight adiponectin correlates with insulin sensitivity in patients with hepatitis C genotype 3, but not genotype 1 infection. American Journal of Gastroenterology, 100 12: 2717-2723. doi:10.1111/j.1572-0241.2005.00311.x 70   39 Cited 47 times in Scopus47 0
Luo, Xiao, Hutley, Louise J., Webster, Julie A., Kim, Yu-Hee, Liu, Dong-Fang, Newell, Felicity S., Widberg, Charlotte H., Bachmann, Anthony, Turner, Nigel, Schmitz-Peiffer, Carsten, Prins, Johannes B., Yang, Gong-She and Whitehead, Jonathan P. (2012) Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors. Diabetes, 61 1: 124-136. doi:10.2337/db11-0998 73 4 13 Cited 14 times in Scopus14 1
Dib, K, Whitehead, JP, Humphreys, PJ, Soos, MA, Baynes, KCR, Kumar, S, Harvey, T and O'Rahilly, S (1998) Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly - A disorder characterized by selective postreceptor insulin resistance. Journal of Clinical Investigation, 101 5: 1111-1120. doi:10.1172/JCI119884 4   33 0
Su, Hua, Gunter, Jennifer H., de Vries, Melissa, Connor, Tim, Wanyonyi, Stephen, Newell, Felicity S., Segal, David, Molero, Juan Carlos, Reizes, Ofer, Prins, Johannes B., Hutley, Louise J., Walder, Ken and Whitehead, Jonathan P. (2009) Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity. Biochemical and Biophysical Research Communications, 386 2: 351-355. doi:10.1016/j.bbrc.2009.06.040 160   5 Cited 6 times in Scopus6 0
Su, H, Newell, F, Hutley, L, Prins, J and Whitehead, J (2005). Inosine-5 ' monophosphate dehydrogenase (IMPDH) activity is essential for adipogenesis. In: Diabetes. 65th Annual Meeting of the American-Diabetes-Association, San Diego Ca, (A441-A441). Jun 10-14, 2005. 10   0

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